A Phase 1 Study of Multiple Escalating Oral Doses of PF-07081532 in Adult Participants With Type 2 Diabetes Mellitus
Condition:   Diabetes Mellitus Type 2 Interventions:   Drug: PF-07081532;   Other: Placebo;   Drug: Clopidogrel Sponsor:   Pfizer Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 12, 2020 Category: Research Source Type: clinical trials

Multiple Escalating Oral Dose Studyb of PF-07081532 in Adult Participants With Type 2 Diabetes Mellitus
Condition:   Diabetes Mellitus Type 2 Interventions:   Drug: PF-07081532;   Other: Placebo;   Drug: Clopidogrel Sponsor:   Pfizer Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 12, 2020 Category: Research Source Type: clinical trials

Ticagrelor and preconditioning in patients with stable coronary artery disease (TAPER-S): a randomized pilot clinical trial
This study started in 2018 with the aim of enrolling 100 patients. Based on the rate of negative FFR up to 30% and a drop-out rate up to 10%, we expect to detect an absolute difference of 4 mm among the study arms in the mean change of ST elevation fo llowing repeated balloon inflations. All study procedures were reviewed and approved by the Ethical Committee of the Catholic University of Sacred Heart.DiscussionTicagrelor might improve ischemia tolerance and microvascular function compared to clopidogrel, and these effects might translate to better long-term clinical outcomes.Trial registrationEudraCT No.2016 &ndash...
Source: Trials - February 17, 2020 Category: Research Source Type: clinical trials

Appropriate Duration of Anti-Platelet and Thrombotic Strategy After 12 Months in Patients With Atrial Fibrillation Treated With Drug Eluting Stents
Condition:   Atrial Fibrillation Interventions:   Drug: Apixaban monotherapy;   Drug: Dual therapy with apixaban and clopidogrel Sponsor:   Yonsei University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 31, 2020 Category: Research Source Type: clinical trials

Ticagrelor in Remote Ischemic Preconditioning Study
Condition:   Periprocedural Myocardial Infarction Interventions:   Drug: Ticagrelor;   Procedure: Remote Ischemic Preconditioning;   Drug: Clopidogrel Sponsor:   Hellenic Society of Interventional Cardiology Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 22, 2019 Category: Research Source Type: clinical trials

Effect of Tegoprazan or RAPA113 on Pharmacodynamics/Pharmacokinetics of Clopidogrel in Healthy Male Volunteers
Condition:   Healthy Interventions:   Drug: Clopidogrel 75mg;   Drug: Tegoprazan 50 mg;   Drug: RAPA113 Sponsor:   CJ HealthCare Corporation Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 21, 2019 Category: Research Source Type: clinical trials