New NIH Resource to Analyze COVID-19 Literature: The COVID-19 Portfolio Tool
George Santangelo, Ph.D., Director of NIH Office of Portfolio Analysis In the past few months, the scientific community has ramped up research in response to the SARS‑CoV‑2 pandemic; dozens of peer-reviewed articles and preprints on this topic are being added to the literature every day (Figure 1). This rapidly expanding effort has created a need for a human-curated resource to explore and analyze advances in SARS‑CoV‑2/COVID-19 research as they accumulate in real time. To address this need, the NIH Office of Portfolio Analysis (OPA) has assembled a comprehensive portfolio of COVID‑19 publications and preprin...
Source: NIH Extramural Nexus - April 15, 2020 Category: Research Authors: George Santangelo Tags: blog Open Mike citations coronavirus COVID-19 portfolio analysis Source Type: funding

The Effect of Different Preparation Methods on the In Vitro and In Vivo Performance of Solid Dispersion Formulations (U01)
The objective of this study is to investigate the in vitro and in vivo performance for solid dispersion drug products made from different manufacturing processes or polymer carriers, as well as their performance consistency during storage and among batches. The investigation should identify critical process parameters and critical quality attributes for solid dispersion made from different preparation methods, and develop discriminating analytical methods. Detailed Descriptions: The following studies should be conducted for the purpose of this project: (1) Identify model drugs, and prepare amorphous solid dispersion us...
Source: Grants.gov - April 18, 2014 Category: Research Tags: Health Science and Technology and other Research and Development Source Type: funding