TWiV 1096: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin highlights measles outbreaks throughout the continental US, reviews recent statistics on the circulation of respiratory syncytial virus, influenza and SARS-CoV-2 before discussing if vaccination protected children from the development of long COVID or cardiovascular diseases associated with virus infection, revised guidelines SARS-CoV-2 treatment and how to treat respiratory viral infections, continues to dispel the myth of viral rebound, when to use steroids and the benefits of convalescent plasma, how COVID-19 effects the autonomic nervous system, and if nirmatrelvir-ritonavir p...
Source: This Week in Virology - MP3 Edition - March 16, 2024 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1076: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin highlights global circulation of Mpox virus, reviews the most recent statistics on the circulation of respiratory syncytial virus, influenza virus and SARS-CoV-2 virus in the US, and discusses the clinical outcome of hospitalized children under 5 years infected with SARS-CoV-2, the perinatal and neonatal outcomes including adverse effects of SARS-CoV-2 infection and virus transmission in Italy between early 2020 and 2022, the guidelines to improve home ventilation, the safety and efficacy of the oral anti-viral molnupiravir and the use of convalescent plasma as a long term treatme...
Source: This Week in Virology - MP3 Edition - January 6, 2024 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1074: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses the outcomes of SARS-CoV-2, influenza and respiratory syncytial virus infection in pediatric communities under the age of 18 years, the treatment of infants with the human monoclonal anti-respiratory syncytial virus antibody to prevent hospitalizations, most recent statistics on the circulation of respiratory syncytial virus, influenza virus and SARS-CoV-2 virus in the US, how the SARS-CoV-2/COVID-19 pandemic affected school attendance and child healthcare, how exposure length influenced transmission of SARS-CoV-2, how the durability of the anti-SARS-CoV-2 antibody respo...
Source: This Week in Virology - MP3 Edition - December 30, 2023 Category: Virology Authors: VIncent Racaniello Source Type: podcasts

TWiV 1072: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses the annual economic burden of respiratory syncytial virus in adults in the US, recombinant or standard-dose influenza vaccine in adults under 65 years of age, maternal vaccine effectiveness against influenza-associated hospitalizations and emergency department visits in iInfants, influenza positive tests reported to CDC by US clinical laboratories, update on COVID-19, risk of severe maternal morbidity associated with SARS-CoV-2 infection during pregnancy, COVID-19 rapid antigen tests with self-collected vs health care worker–collected nasal and throat swab specimens, op...
Source: This Week in Virology - MP3 Edition - December 23, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1064: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses progress toward measles elimination, risk of severe coronavirus disease 2019 despite vaccination in patients requiring treatment with immune-suppressive drugs, symptoms, viral loads, and rebound among COVID-19 outpatients treated with nirmatrelvir/ritonavir compared to propensity score matched untreated individuals, late administration and corticosteroid usage explain inefficacy in COVID-19 convalescent plasma trial, higher-dose fluvoxamine and time to sustained recovery in outpatients with COVID-19, recombinant C1 inhibitor in the prevention of severe COVID-19, and Epst...
Source: This Week in Virology - MP3 Edition - November 25, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1062: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses coverage with selected vaccines and exemption from school vaccine requirements among children in kindergarten, seasonality of endemic COVID-19, mRNA SARS-CoV-2 vaccination before vs during pregnancy and omicron infection among infants, extracting symptoms from free-text responses using ChatGPT among COVID-19 cases in Hong Kong, SARS-CoV-2 virologic rebound with nirmatrelvir–ritonavir therapy, optimization of antiviral therapy in immunocompromised COVID-19 patients, a study to learn about the study medicines (nirmatrelvir plus ritonavir) in people aged 12 years or older...
Source: This Week in Virology - MP3 Edition - November 18, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1058: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses health worker–perceived working conditions and symptoms of poor mental health, Mpox neutralizing antibodies at 6 months from mpox infection or MVA-BN vaccination, newborn and early infant outcomes following maternal COVID-19 vaccination during pregnancy, duration of SARS-CoV-2 culturable virus shedding in children, prescribing outcomes in outpatients treated with nirmatrelvir–ritonavir for COVID-19 in an interdisciplinary community clinic, Nirmatrelvir and molnupiravir and post-COVID-19 condition in older patients, optimal duration of systemic corticosteroids in COVI...
Source: This Week in Virology - MP3 Edition - November 4, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1056: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses health worker–perceived working conditions and symptoms of poor mental health, Mpox neutralizing antibodies at 6 months from mpox infection or MVA-BN vaccination, newborn and early infant outcomes following maternal COVID-19 vaccination during pregnancy, duration of SARS-CoV-2 culturable virus shedding in children, prescribing outcomes in outpatients treated with nirmatrelvir–ritonavir for COVID-19 in an interdisciplinary community clinic, Nirmatrelvir and molnupiravir and post-COVID-19 condition in older patients, optimal duration of systemic corticosteroids in COVI...
Source: This Week in Virology - MP3 Edition - October 28, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1052: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses disease severity of RSV compared with COVID-19 and Influenza among hospitalized adults aged ≥60 years, antiviral efficacy of Molnupiravir versus ritonavir-boosted nirmatrelvir in patients with early symptomatic COVID-19, Nirmatrelvir-Ritonavir and COVID-19 mortality and hospitalization among patients with vulnerability to covid-19 complications, antibiotic use among hospitalized patients with COVID-19 in the United States, one week of oral Camostat vs Placebo in nonhospitalized adults with mild-to-moderate COVID-19, assessment of the available therapeutic approaches fo...
Source: This Week in Virology - MP3 Edition - October 14, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1046: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses wastewater surveillance data as a complement to emergency department visit data for tracking the incidence of influenza A and RSV, chatbot-delivered online intervention to promote seasonal Influenza vaccination during the COVID-19 pandemic, temporal assessment of disparities in California COVID-19 mortality by industry, modeling the impact of a high-uptake bivalent booster scenario on the COVID-19 burden and healthcare costs in New York City, can high COVID-19 vaccination rates in adults help protect unvaccinated children, Nirmatrelvir/Ritonavir use and hospitalizations ...
Source: This Week in Virology - MP3 Edition - September 23, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1038: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses modeling poliovirus transmission and responses in New York State, FDA approves first vaccine for pregnant individuals to prevent RSV in infants, prevention and control of seasonal influenza with vaccines: recommendations of the Advisory Committee on Immunization Practices, Nirmatrelvir resistance – de novo E166V/L50V mutations in an immunocompromised patient treated with prolonged nirmatrelvir/ritonavir monotherapy leading to clinical and virological treatment failure, incidence of new-onset hypertension post–COVID-19: comparison with influenza, and post-acute sequel...
Source: This Week in Virology - MP3 Edition - August 26, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1036: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses Florida local transmission of dengue cases reported in Broward and Miami-Dade counties, infants admitted to US intensive care units for RSV infection during the 2022 seasonal peak, long-term risk of death and readmission after hospital admission with COVID-19 among older adults, safety profile and clinical and virological outcomes of Nirmatrelvir-Ritonavir treatment in patients with advanced chronic kidney disease and COVID-19, Fluvoxamine vs placebo for outpatients with symptomatic COVID-19, the effect of corticosteroids, antibiotics, and anticoagulants on the developme...
Source: This Week in Virology - MP3 Edition - August 19, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1032: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses predicting COVID-19 incidence using wastewater surveillance data, use of wastewater metrics to track COVID-19 in the US, wastewater-based epidemiology predicts COVID-19-induced weekly new hospital admissions in over 150 USA counties, association between duration of SARS-CoV-2 positivity and long COVID, rapid direct detection of SARS-CoV-2 aerosols in exhaled breath at the point of care, effectiveness of oral Nirmatrelvir/Ritonavir vs. intravenous three-day Remdesivir in preventing progression to severe COVID-19, NIH launching of several phase 2 long-COVID treatment trial...
Source: This Week in Virology - MP3 Edition - August 5, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1025: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses the new risk assessment for the H5N1 avian flu viruses, the development of monoclonal antibody-based blocking ELISA for detecting SARS-CoV-2 exposure in animals, repeated antibiotic exposure and risk of hospitalization and death following COVID-19 infection, COVID-19 rebound study: a prospective cohort study to evaluate viral and symptom rebound differences in participants treated with Nirmatrelvir plus Ritonavir versus untreated controls, exaggerated blood pressure elevation in response to orthostatic challenge a post-acute sequelae of SARS-CoV-2 infection (PASC) after ...
Source: This Week in Virology - MP3 Edition - July 15, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1022: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses autochthonous leprosy in the United States, a systematic review to identify novel clinical characteristics of Mpox virus infection and therapeutic and preventive strategies to combat the virus, two-year duration of immunity of inactivated poliovirus vaccine, evaluation of novel oral polio vaccine type 2 SIA impact in a large outbreak of circulating vaccine-derived poliovirus in Nigeria, performance of rapid antigen tests to detect symptomatic and asymptomatic SARS-CoV-2 Infection, effectiveness of the COVID-19 bivalent vaccine, oral Nirmatrelvir and Ritonavir for COVID-1...
Source: This Week in Virology - MP3 Edition - July 8, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts