NCBI Posters at the Biology of Genomes Meeting
May 10-14, 2022 We are looking forward to the Biology of Genomes meeting, which will focus on “DNA sequence variation and its role in molecular evolution, population genetics and complex diseases, comparative genomics, large-scale studies of gene and protein expression, and genomic approaches to ecological systems.” NCBI will present three posters to highlight our Comparative … Continue reading NCBI Posters at the Biology of Genomes Meeting → The post NCBI Posters at the Biology of Genomes Meeting appeared first on NCBI Insights. (Source: NCBI Insights)
Source: NCBI Insights - May 3, 2022 Category: Databases & Libraries Authors: NCBI Staff Tags: What's New CGR dbGaP Allele Frequency Aggregator (ALFA) Source Type: news

New ClusteredNR database: faster searches and more informative BLAST results
Reduced redundancy. Faster searches. More diverse proteins and organisms in your BLAST results. Check out our new ClusteredNR database – derived from the default BLAST protein nr database by clustering sequences at 90% identity / 90% length (details below).  Get quicker results and access to information about distribution of your hits across a wider range … Continue reading New ClusteredNR database: faster searches and more informative BLAST results → The post New ClusteredNR database: faster searches and more informative BLAST results appeared first on NCBI Insights. (Source: NCBI Insights)
Source: NCBI Insights - May 2, 2022 Category: Databases & Libraries Authors: NCBI Staff Tags: What's New Basic Local Alignment Search Tool (BLAST) CGR Homologs Protein BLAST (BLASTp) Source Type: news

Logging into your My NCBI account is now easier, faster and more secure!
As of June 2022, you will be required to login using a 3rd-party option. As we announced previously, beginning June 2022, you will no longer be able to log into your My NCBI account with your My NCBI username and password. We launched our Password Retirement Wizard last summer to help you link a 3rd-party … Continue reading Logging into your My NCBI account is now easier, faster and more secure! → The post Logging into your My NCBI account is now easier, faster and more secure! appeared first on NCBI Insights. (Source: NCBI Insights)
Source: NCBI Insights - April 27, 2022 Category: Databases & Libraries Authors: NCBI Staff Tags: What's New My Bibliography My NCBI SciENcv Source Type: news

Announcing GenBank Release 249.0
GenBank release 249.0 (4/19/2022) is now available on the NCBI FTP site. This release has 17.85 trillion bases and 2.66 billion records. The current release has 237,520,318 traditional records containing 1,266,154,890,918 base pairs of sequence data. There are also 1,781,374,217 WGS records containing 16,071,520,702,170 base pairs of sequence data, 534,770,586 bulk-oriented TSA records containing 474,421,076,448 … Continue reading Announcing GenBank Release 249.0 → The post Announcing GenBank Release 249.0 appeared first on NCBI Insights. (Source: NCBI Insights)
Source: NCBI Insights - April 22, 2022 Category: Databases & Libraries Authors: NCBI Staff Tags: What's New GenBank Source Type: news

NCBI ALFA Project at Bio-IT World 2022 Hackathon
Announcing the Allele Frequency Aggregator (ALFA) Project as part of the Bio-IT World 2022 Hackathon: Visualization of NCBI ALFA Variants Join NCBI at the Bio-IT World 2022 Hackathon on May 4-5, 2022 to learn about and work with data from our ALFA project! The primary goal of this hackathon project is to develop a novel … Continue reading NCBI ALFA Project at Bio-IT World 2022 Hackathon → The post NCBI ALFA Project at Bio-IT World 2022 Hackathon appeared first on NCBI Insights. (Source: NCBI Insights)
Source: NCBI Insights - April 21, 2022 Category: Databases & Libraries Authors: NCBI Staff Tags: What's New ClinVar Database of human genomic structural variation (dbVar) dbGaP Allele Frequency Aggregator (ALFA) Single Nucleotide Polymorphism Database (dbSNP) Source Type: news

Introducing SARS-CoV-2 Variants Overview, NLM ’s latest tool in the fight against COVID-19 
The National Center for Biotechnology Information (NCBI) at the National Library of Medicine (NLM) has released a new resource, called the SARS-CoV-2 Variants Overview, that aggregates data related to SARS-CoV-2 variants from sequences available in NCBI’s GenBank and Sequence Read Archive (SRA) databases. SARS-CoV-2 Variants Overview, a freely available online dashboard, was developed with guidance from the TRACE Working Group as … Continue reading Introducing SARS-CoV-2 Variants Overview, NLM’s latest tool in the fight against COVID-19  → The post Introducing SARS-CoV-2 Variants Overview, NLM’s la...
Source: NCBI Insights - April 20, 2022 Category: Databases & Libraries Authors: NCBI Staff Tags: What's New GenBank Open data SARS-CoV-2 Sequence Read Archive (SRA) STRIDES Source Type: news

New RefSeq Annotations!
In February and March, the NCBI Eukaryotic Genome Annotation Pipeline released thirty-seven new annotations in RefSeq for the following organisms: Belonocnema kinseyi (wasp) Daphnia pulex (common water flea) Daphnia pulicaria (crustacean) Dermatophagoides farinae (American house dust mite) Diprion similis (hymenopteran) Drosophila willistoni (fly) Equus quagga burchellii (Burchell’s zebra) (pictured) Gallus gallus (chicken) Haliotis rubra (blacklip … Continue reading New RefSeq Annotations! → The post New RefSeq Annotations! appeared first on NCBI Insights. (Source: NCBI Insights)
Source: NCBI Insights - April 13, 2022 Category: Databases & Libraries Authors: NCBI Staff Tags: What's New Eukaryotic genome annotation Genome Data Viewer (GDV) RefSeq Source Type: news

New feature in the MSA viewer: Search for a short sequence
We’re reading and incorporating your feedback! As requested, you can now search for sequences in our Multiple Sequence Alignment (MSA) Viewer. You can search the anchor or consensus sequence of a multiple alignment for short sequence strings. This new feature allows you to: Look for a sequence motif in DNA or protein alignments in order … Continue reading New feature in the MSA viewer: Search for a short sequence → The post New feature in the MSA viewer: Search for a short sequence appeared first on NCBI Insights. (Source: NCBI Insights)
Source: NCBI Insights - April 12, 2022 Category: Databases & Libraries Authors: NCBI Staff Tags: What's New Multiple Sequence Alignment Viewer (MSAV) Source Type: news

MANE is published in Nature!
We are delighted to announce that three and a half years of hard work by the collaborative team that brought you the Matched Annotation from NCBI and EMBL-EBI (MANE) dataset has culminated in a full article in the April 14 issue of Nature!  We invite you to read the online article to learn more about … Continue reading MANE is published in Nature! → The post MANE is published in Nature! appeared first on NCBI Insights. (Source: NCBI Insights)
Source: NCBI Insights - April 6, 2022 Category: Databases & Libraries Authors: NCBI Staff Tags: What's New Source Type: news

NCBI hidden Markov models (HMM) release 8.0 now available!
Release 8.0 of the NCBI Hidden Markov models (HMM), used by the Prokaryotic Genome Annotation Pipeline (PGAP), is now available for download. You can search this collection against your favorite prokaryotic proteins to identify their function using the HMMER sequence analysis package. The 8.0 release contains 15,358 models, including 160 that are new since 7.0. … Continue reading NCBI hidden Markov models (HMM) release 8.0 now available! → The post NCBI hidden Markov models (HMM) release 8.0 now available! appeared first on NCBI Insights. (Source: NCBI Insights)
Source: NCBI Insights - March 31, 2022 Category: Databases & Libraries Authors: NCBI Staff Tags: What's New Gene Ontology (GO) Hidden Markov Models (HMM) HMMER NCBI Prokaryotic Genome Annotation Pipeline (PGAP) Prokaryotes Source Type: news

BLAST+ 2.13.0 now available with SRA BLAST, ARM Linux executables, and database metadata
BLAST+ 2.13.0  includes several important new features including SRA BLAST programs, ARM Linux executables, and the ability to produce database metadata as well as some important improvements, and a few bug fixes.  You can download the new BLAST release from the FTP site. New features SRA / WGS BLAST (blastn_vdb, tblastn_vdb) Beginning with this release, … Continue reading BLAST+ 2.13.0 now available with SRA BLAST, ARM Linux executables, and database metadata → The post BLAST+ 2.13.0 now available with SRA BLAST, ARM Linux executables, and database metadata appeared first on NCBI Insights. (Source: NCBI Insights)
Source: NCBI Insights - March 29, 2022 Category: Databases & Libraries Authors: NCBI Staff Tags: What's New Basic Local Alignment Search Tool (BLAST) Nucleotide BLAST (blastn) Protein BLAST (BLASTp) Sequence Read Archive (SRA) Source Type: news

Using NCBI resources to research, detect, and treat genetic phenotypes
Clinical Genetics Information at Your Fingertips NCBI offers a portfolio of medical genetics resources to help you research, diagnose, and treat diseases and conditions. You can easily access our data and tools through the Medical Genetics and Human Variation page of the NCBI website. We also encourage you to join our community of thousands of … Continue reading Using NCBI resources to research, detect, and treat genetic phenotypes → The post Using NCBI resources to research, detect, and treat genetic phenotypes appeared first on NCBI Insights. (Source: NCBI Insights)
Source: NCBI Insights - March 25, 2022 Category: Databases & Libraries Authors: NCBI Staff Tags: What's New ACMG2022 ClinicalTrials.gov ClinVar Database of Genotypes and Phenotypes (dbGaP) dbGaP Allele Frequency Aggregator (ALFA) GeneReviews Genetic Testing Registry (GTR) MedGen Medical Genetic Summaries (MGS) Medical genetics S Source Type: news

Test Server for the PubMed API (E-utilities) is Now Available
Official update scheduled to launch June 2022  As previously announced, we will be moving to an updated version of the E-utilities API for PubMed. We are planning to delay this change until June 2022 to give you time to test your API calls on the new service, report issues, and provide your feedback. Don’t wait until … Continue reading Test Server for the PubMed API (E-utilities) is Now Available → The post Test Server for the PubMed API (E-utilities) is Now Available appeared first on NCBI Insights. (Source: NCBI Insights)
Source: NCBI Insights - March 24, 2022 Category: Databases & Libraries Authors: NCBI Staff Tags: What's New API e-utilities PubMed Source Type: news

Introducing ElasticBLAST – BLAST ® is now easier, bigger, and faster on the Cloud!
ElasticBLAST is a new tool that helps you run BLAST searches on the cloud. ElasticBLAST is perfect for you if you have thousands to millions of queries to our Basic Local Alignment Search Tool (BLAST ®), or if you want to use cloud infrastructure for your searches. ElasticBLAST can handle large searches that are not … Continue reading Introducing ElasticBLAST – BLAST® is now easier, bigger, and faster on the Cloud! → The post Introducing ElasticBLAST – BLAST® is now easier, bigger, and faster on the Cloud! appeared first on NCBI Insights. (Source: NCBI Insights)
Source: NCBI Insights - March 23, 2022 Category: Databases & Libraries Authors: NCBI Staff Tags: What's New Basic Local Alignment Search Tool (BLAST) Cloud computing ElasticBLAST Source Type: news

New PMC Website Design is Live!
We have launched a fresh look and feel to the PubMed Central (PMC) website, which marks the first step of an ongoing modernization effort. The updated website will allow us to make continuous enhancements to PMC based on your feedback.    What Has Changed?    Now when you visit PMC’s homepage, you will see:   A redesigned and reorganized homepage   … Continue reading New PMC Website Design is Live! → The post New PMC Website Design is Live! appeared first on NCBI Insights. (Source: NCBI Insights)
Source: NCBI Insights - March 21, 2022 Category: Databases & Libraries Authors: NCBI Staff Tags: What's New PubMed Central (PMC) Source Type: news