Conserved Domain Database version 3.20 is available!
A new version of the Conserved Domain Database (CDD) is now available. Version 3.20 contains 1,614 new or updated NCBI/CDD-curated domains and now mirrors Pfam version 34 as well as new models from the NCBIfam collection. Fine-grained classifications of the [(+)ssRNA] virus RNA-dependent RNA polymerase catalytic domain, RING-finger/U-box, dimerization/docking domains of the cAMP-dependent protein kinase … Continue reading Conserved Domain Database version 3.20 is available! → (Source: NCBI Insights)
Source: NCBI Insights - September 26, 2022 Category: Databases & Libraries Authors: NCBI Staff Tags: What's New Comparative Genomics Resource (CGR) Conserved Domains Database (CDD) Protein Source Type: news
RefSeq release 214 is available!
RefSeq release 214 is now available online, from the FTP site, and through NCBI’s Entrez programming utilities, E-utilities. This full release incorporates genomic, transcript, and protein data available as of September 12, 2022, and contains 328,588,569 records, including 239,609,016 proteins, 47,387,931 RNAs, and sequences from 123,394 organisms. The release is provided in several directories as a complete … Continue reading RefSeq release 214 is available! → (Source: NCBI Insights)
Source: NCBI Insights - September 21, 2022 Category: Databases & Libraries Authors: NCBI Staff Tags: What's New Comparative Genomics Resource (CGR) e-utilities Eukaryotic genome annotation RefSeq Source Type: news
Join NCBI virtually at the Biodiversity Genomics 2022 conference
Learn about the NIH Comparative Genomics Resource (CGR) Project The Biodiversity Genomics conference will take place virtually, October 2-7, 2022. This event is hosted by the Earth BioGenome Project and is open and free for all to attend. NCBI staff will present a variety of recorded talks and posters highlighting various elements of the NIH … Continue reading Join NCBI virtually at the Biodiversity Genomics 2022 conference → (Source: NCBI Insights)
Source: NCBI Insights - September 19, 2022 Category: Databases & Libraries Authors: NCBI Staff Tags: What's New Comparative Genome Viewer (CGV) Comparative Genomics Resource (CGR) Datasets Source Type: news
NCBI hidden Markov models (HMM) release 10.0 now available!
Release 10.0 of the NCBI Hidden Markov models (HMM) used by the Prokaryotic Genome Annotation Pipeline (PGAP) is now available for download. You can search this collection against your favorite prokaryotic proteins to identify their function using the HMMER sequence analysis package. The 10.0 release contains 15,360 models maintained by NCBI, including 228 that are … Continue reading NCBI hidden Markov models (HMM) release 10.0 now available! → (Source: NCBI Insights)
Source: NCBI Insights - September 15, 2022 Category: Databases & Libraries Authors: NCBI Staff Tags: What's New Gene Ontology (GO) Hidden Markov Models (HMM) HMMER NCBI Prokaryotic Genome Annotation Pipeline (PGAP) Prokaryotes Source Type: news
Coming soon: Updated PubMed E-utilities!
PubMed will be moving to an updated version of the E-utilities API on November 15, 2022. As previously announced, this updated version of E-utilities will use the same technology as the web version of PubMed released in 2020. So, search results returned by the updated ESearch E-utility will now match those of the PubMed.gov website. This update only affects … Continue reading Coming soon: Updated PubMed E-utilities! → (Source: NCBI Insights)
Source: NCBI Insights - September 13, 2022 Category: Databases & Libraries Authors: NCBI Staff Tags: What's New API e-utilities PubMed Source Type: news
New ClinVar graphical display
Maps clinically significant variants by gene and position! ClinVar is a freely accessible, public archive of reports of the relationships between human variations and phenotypes, with supporting evidence at NLM/NCBI. To help you access your variants of interest quickly, ClinVar is introducing an all-new visualization tool in the search results. This graphical display provides an … Continue reading New ClinVar graphical display → (Source: NCBI Insights)
Source: NCBI Insights - August 30, 2022 Category: Databases & Libraries Authors: NCBI Staff Tags: What's New ClinVar Human variant data Variation Source Type: news
Celebrating 1 Year of NCBI Virtual Outreach Events
We launched the NCBI Virtual Outreach Event series in the fall of 2021 to expand our online outreach to a worldwide audience of people who use NCBI resources for biological/biomedical research, science education, and clinical applications. Our virtual outreach events include interactive workshops, webinars, and codeathons. In the past year, we have hosted 34 virtual … Continue reading Celebrating 1 Year of NCBI Virtual Outreach Events → (Source: NCBI Insights)
Source: NCBI Insights - August 26, 2022 Category: Databases & Libraries Authors: NCBI Staff Tags: What's New Codeathon Education NCBI Education Training Webinars Workshop Source Type: news
Top 3 reasons to use ElasticBLAST
ElasticBLAST is a new way to BLAST large numbers of queries, faster and on the cloud. Here are the top three reasons you should use ElasticBLAST: 1. ElasticBLAST can handle much LARGER queries! ElasticBLAST can search query sets that have hundreds to millions of sequences and against BLAST databases of all sizes. 2. ElasticBLAST is … Continue reading Top 3 reasons to use ElasticBLAST → (Source: NCBI Insights)
Source: NCBI Insights - August 23, 2022 Category: Databases & Libraries Authors: NCBI Staff Tags: What's New BLAST Cloud computing ElasticBLAST STRIDES Source Type: news
Announcing GenBank Release 251.0
GenBank release 251.0 (8/15/2022) is now available on the NCBI FTP site. This release has 19.55 trillion bases and 2.94 billion records. The current release has 239,915,786 traditional records containing 1,492,800,704,497 base pairs of sequence data. There are also 2,024,099,677 WGS records containing 17,511,809,676,629 base pairs of sequence data, 560,196,830 bulk-oriented TSA records containing 497,501,380,386 … Continue reading Announcing GenBank Release 251.0 →
The post Announcing GenBank Release 251.0 appeared first on NCBI Insights. (Source: NCBI Insights)
Source: NCBI Insights - August 18, 2022 Category: Databases & Libraries Authors: NCBI Staff Tags: What's New GenBank Source Type: news
Announcing new links and annotations on Conserved Domain Search results!
Conserved Domain Search (CD Search) results now show domain architecture information and other annotations that further characterize predicted domain and protein function. These include links to PubMed, Gene Ontology (GO) terms, Enzyme Commission (EC) numbers, and the SPARCLE Domain Architecture Viewer. You can use these links on the results to find literature (PubMed), assign biological … Continue reading Announcing new links and annotations on Conserved Domain Search results! →
The post Announcing new links and annotations on Conserved Domain Search results! appeared first on NCBI Insights. (Source: NCBI Insights)
Source: NCBI Insights - August 10, 2022 Category: Databases & Libraries Authors: NCBI Staff Tags: What's New Basic Local Alignment Search Tool (BLAST) Comparative Genomics Resource (CGR) Conserved Domains Database (CDD) Gene Ontology (GO) Subfamily Protein Architecture Labeling Engine (SPARCLE) Source Type: news
New annotations in RefSeq
In June and July, the NCBI Eukaryotic Genome Annotation Pipeline released twenty-six new annotations in RefSeq for the following organisms: Anopheles coluzzii (mosquito) Anopheles funestus (African malaria mosquito) Astyanax mexicanus (Mexican tetra) Athalia rosae (coleseed sawfly) Bactrocera dorsalis (oriental fruit fly) Brassica napus (rape) Brienomyrus brachyistius (bony fish) Canis lupus dingo (dingo) (pictured) Caretta caretta (Loggerhead turtle) Dendroctonus ponderosae … Continue reading New annotations in RefSeq →
The post New annotations in RefSeq appeared first on NCBI Insights. (Source: NCBI Insights)
Source: NCBI Insights - August 8, 2022 Category: Databases & Libraries Authors: NCBI Staff Tags: What's New Comparative Genomics Resource (CGR) Datasets Eukaryotic genome annotation Genome Data Viewer (GDV) RefSeq Source Type: news
New Features in iCn3D: Expanded Analysis of AlphaFold Structures, Virtual & Augmented Reality
We have added several exciting features to our interactive, web-based 3D-structure viewer, iCn3D! These new features allow you to compare AlphaFold Predicted structures to available structures as well as experience 3D structures with virtual and augmented reality. Learn more about tool updates here. AlphaFold is an artificial intelligence system designed to compute protein 3D structure … Continue reading New Features in iCn3D: Expanded Analysis of AlphaFold Structures, Virtual & Augmented Reality →
The post New Features in iCn3D: Expanded Analysis of AlphaFold Structures, Virtual & Augmented Reality a...
Source: NCBI Insights - August 1, 2022 Category: Databases & Libraries Authors: NCBI Staff Tags: What's New Source Type: news
Foreign Contamination Screen (FCS) tool for GenBank submissions
We are excited to introduce a Foreign Contamination Screen (FCS) tool that you can now run yourself, with enhanced contaminant detection sensitivity to improve your genome assemblies and facilitate high-quality data submissions to GenBank. If you submit genome assembly data to GenBank, the FCS tool is for you! What is the FCS tool? FCS, a … Continue reading Foreign Contamination Screen (FCS) tool for GenBank submissions →
The post Foreign Contamination Screen (FCS) tool for GenBank submissions appeared first on NCBI Insights. (Source: NCBI Insights)
Source: NCBI Insights - July 28, 2022 Category: Databases & Libraries Authors: NCBI Staff Tags: What's New Comparative Genomics Resource (CGR) GenBank Genome assemblies RefSeq VecScreen Source Type: news
Announcing the NCBI Datasets SARS-CoV-2 taxonomy page
Need SARS-CoV-2 assembled genome sequences or specific SARS-CoV-2 protein sequences? You can find them on the new SARS-CoV-2 taxonomy page brought to you by NCBI Datasets. The NCBI Datasets SARS-CoV-2 taxonomy page brings you both SARS-CoV-2 genomes and proteins, basic information about SARS-CoV-2, and connections to related NCBI pages, all in one place (see Figures … Continue reading Announcing the NCBI Datasets SARS-CoV-2 taxonomy page →
The post Announcing the NCBI Datasets SARS-CoV-2 taxonomy page appeared first on NCBI Insights. (Source: NCBI Insights)
Source: NCBI Insights - July 26, 2022 Category: Databases & Libraries Authors: NCBI Staff Tags: What's New Datasets GDH NCBI Virus SARS-CoV-2 Source Type: news
RefSeq Release 213
is now available online, from the FTP site and through NCBI’s Entrez programming utilities, E-utilities. This full release incorporates genomic, transcript, and protein data available as of July 11, 2022, and contains 321,282,996 records, including 234,520,053 proteins, 45,781,716 RNAs, and sequences from 121,461 organisms. The release is provided in several directories as a complete … Continue reading RefSeq Release 213 →
The post RefSeq Release 213 appeared first on NCBI Insights. (Source: NCBI Insights)
Source: NCBI Insights - July 18, 2022 Category: Databases & Libraries Authors: NCBI Staff Tags: What's New Eukaryotic genome annotation RefSeq Source Type: news
