Diet and Cognitive Decline: Untangling the EvidenceDiet and Cognitive Decline: Untangling the Evidence
Flavonols and omega-3 consumption integrated with clinical precision medicine could reduce the risk for cognitive decline and Alzheimer's. Medscape Neurology (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - June 7, 2016 Category: Neurology Tags: Neurology & Neurosurgery Commentary Source Type: news

Young Men With MS at Higher Risk for Psychiatric IllnessYoung Men With MS at Higher Risk for Psychiatric Illness
Multiple sclerosis could act as a 'final trigger' in those who are susceptible to bipolar disorder and schizophrenia, researchers say. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - June 7, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Drug Proves Effective in Reducing MigrainesDrug Proves Effective in Reducing Migraines
At 1 year, almost 20% of patients with migraine had a full response to an investigational drug, AMG344, which blocks a key receptor causing headaches. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - June 7, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Aura Symptoms Highly Variable in Patients With MigraineAura Symptoms Highly Variable in Patients With Migraine
Only about half of patients have nausea during a migraine attack, new prospectively collected data suggest. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - June 3, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Rapid Estrogen Decline Confirmed as Migraine Contributor Rapid Estrogen Decline Confirmed as Migraine Contributor
A new study suggests that rapid estrogen decline at the end of the menstrual cycle may make women vulnerable to common triggers for migraine attacks. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - June 3, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

FDA Investigates Skin Reactions With Zecuity Sumatriptan PatchFDA Investigates Skin Reactions With Zecuity Sumatriptan Patch
Reports of serious burns and scarring with the use of the Zecuity sumatriptan transdermal patch for migraine prompts FDA investigation and drug safety communication. News Alerts (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - June 2, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Alert Source Type: news

Migraine, Fibromyalgia Frequently Misdiagnosed as MS Migraine, Fibromyalgia Frequently Misdiagnosed as MS
A study found that in some cases patients were treated for MS for years, exposing them to the dangers and costs of disease-modifying therapies. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - June 2, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

FDA Okays Imaging Agent (Netspot) for Neuroendocrine TumorsFDA Okays Imaging Agent (Netspot) for Neuroendocrine Tumors
The product is the first kit for the preparation of gallium Ga 68 dotatate injection, a PET imaging agent used to detect somatostatin receptor-positive neuroendocrine tumors. FDA Approvals (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - June 2, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Alert Source Type: news

Head Turning Sign May Help Identify Alzheimer's Head Turning Sign May Help Identify Alzheimer's
A new study of patients with dementia showed high sensitivity and predictive value of the test that helps distinguish Alzheimer's from other conditions. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - June 1, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Acceptance, Flexibility Key in Chronic Pain BattleAcceptance, Flexibility Key in Chronic Pain Battle
Acceptance and commitment therapy take on catastrophizing thought patterns that undermine chronic pain. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - June 1, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Quick Screen May Flag Opioid Abuse Risk Quick Screen May Flag Opioid Abuse Risk
Two new reports outline measures that may help quickly identify pain patients at risk for longer-term opioid use or for opioid abuse. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - June 1, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Cannabis Extract Spray Reduces Spasticity in Patients With MNDCannabis Extract Spray Reduces Spasticity in Patients With MND
Italian researchers report positive results from a phase 2 randomized controlled trial of patients with motor neuron diseases, including ALS. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - June 1, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Congress of the European Academy of Neurology (EAN) 2016Congress of the European Academy of Neurology (EAN) 2016
Read clinically focused news coverage of key developments from EAN 2016. Medscape Neurology (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 31, 2016 Category: Neurology Tags: Conference Coverage Source Type: news

School Test Results Lower in Kids Exposed Prenatally to AEDSchool Test Results Lower in Kids Exposed Prenatally to AED
Sixth-graders exposed to an antiepileptic drug, particularly valproate or clonazepam, performed significantly worse than unexposed kids on math and reading tests, new results show. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 31, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

SUDEP Rate Lower in Epilepsy Patients After VNSSUDEP Rate Lower in Epilepsy Patients After VNS
A new large observational study increases the power of previous studies by 100-fold and suggests patients with drug-resistant epilepsy treated with vagus nerve stimulation have a reduced risk of sudden death. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 30, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

VIST: Vertebral Artery Stenting May Reduce Recurrent Stroke VIST: Vertebral Artery Stenting May Reduce Recurrent Stroke
The trial showed a low risk of stenting, and suggested reduced recurrent stroke particularly in patients with extracranial stenosis, but was underpowered. A confirmatory trial will be needed. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 30, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Stem Cells, B Cells, and T Cells in Focus at CMSC Stem Cells, B Cells, and T Cells in Focus at CMSC
Presentations at the upcoming Consortium of Multiple Sclerosis Centers meeting will also shed light on working with patients using alternative treatments, such as medical marijuana and dietary supplements. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 27, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

EMA Launches Major Review After Fatal French Drug TrialEMA Launches Major Review After Fatal French Drug Trial
The agency will review existing guidelines for first-in-human clinical trials with the aim of identifying areas that need revision, with the ultimate goal of making the trials safer. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 27, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Tools Refined to Assess Catastrophizing in Chronic PainTools Refined to Assess Catastrophizing in Chronic Pain
The response to a key catastrophizing measure can predict the risk for opioid misuse, a new study suggests. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 27, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Tracking the Rise of Zika ComplicationsTracking the Rise of Zika Complications
A new look at the timeline of the recent explosion of Zika cases examines what is known about the neuroimmunologic effects. WFN guidelines for these complications are in the works. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 27, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Virtual Reality Ventures Into Real World of Chronic PainVirtual Reality Ventures Into Real World of Chronic Pain
With benefits seen in acute pain and technology becoming more accessible, researchers see encouraging, albeit early, signs of use in chronic pain. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 27, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Pregabalin Linked to Major Birth DefectsPregabalin Linked to Major Birth Defects
Exposure to pregabalin, an antiepileptic also prescribed for pain and psychiatric disorders, during pregnancy is linked to a 3-fold increased risk for major birth defects, a new study suggests. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 24, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

The Myth of Morphine Equivalent Daily Dosage The Myth of Morphine Equivalent Daily Dosage
A new study suggests that a commonly used means of dosing opioid analgesics is flawed. Medscape Neurology (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 24, 2016 Category: Neurology Tags: Neurology & Neurosurgery Expert Column Source Type: news

Buprenorphine 'Underused' in Primary Care as Opioid Abuse SoarsBuprenorphine 'Underused' in Primary Care as Opioid Abuse Soars
Only a small percentage of clinicians in primary care use one of the most important weapons against opioid abuse in the setting of chronic pain, experts say. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 21, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Four Major Neurology UpdatesFour Major Neurology Updates
Dr Merino discusses hot topics at this year's AAN meeting. Medscape Neurology (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 20, 2016 Category: Neurology Tags: Neurology & Neurosurgery Expert Column Source Type: news

Conscious Sedation Same as Anesthetic for Stroke Thrombectomy Conscious Sedation Same as Anesthetic for Stroke Thrombectomy
SIESTA, the first randomized trial comparing general anesthesia and conscious sedation, has shown similar short-term outcomes in stroke patients undergoing endovascular treatment. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 19, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Emotional Expression Shows Benefits vs CBT for Chronic PainEmotional Expression Shows Benefits vs CBT for Chronic Pain
A therapeutic approach encouraging expression of emotions shows improvements in some outcomes over cognitive-behavioral therapy for fibromyalgia and chronic pain in the PAST-FM trial. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 19, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Reassuring Results for tPA on Long-term Mortality in Stroke Reassuring Results for tPA on Long-term Mortality in Stroke
Three-year results from the IST-3 trial show a nonsignificant reduction in mortality for stroke patients receiving thrombolytic therapy. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 19, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Disrupted Sleep Linked to Lower Pain Tolerance, ImpulsivityDisrupted Sleep Linked to Lower Pain Tolerance, Impulsivity
Healthy individuals subjected to forced awakenings similar to those commonly experienced with chronic pain show significant reductions in pain tolerance and other notable changes. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 18, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

APS Issues New Guidance on Medical Marijuana for PainAPS Issues New Guidance on Medical Marijuana for Pain
With patients increasingly turning to herbal cannabis for chronic pain -- legally or not -- the American Pain Society white paper offers clinical guidance and strong suggestions on the need for more research. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 18, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Prognosis After a Transient Ischemic Attack or Minor StrokePrognosis After a Transient Ischemic Attack or Minor Stroke
Studies from more than 10 years ago showed that the risk for a stroke or cardiovascular event after a transient ischemic event was high. Dr Diener discusses a study that re-evaluated this phenomenon. Medscape Neurology (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 17, 2016 Category: Neurology Tags: Neurology & Neurosurgery Commentary Source Type: news

Promising Data With Ketamine in Chronic and Phantom Limb PainPromising Data With Ketamine in Chronic and Phantom Limb Pain
The key to avoiding adverse effects with ketamine is to start at a low dose, says one clinician. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 17, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

'Awake' Lumbar Fusion Offers Eye-Opening Recovery Improvement'Awake' Lumbar Fusion Offers Eye-Opening Recovery Improvement
In a small case series, the innovative approach shortened hospital stay and narcotic use while offering significant improvement in disability. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 14, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Position-Related Neurapraxia Prediction Not Always on TargetPosition-Related Neurapraxia Prediction Not Always on Target
Intraoperative monitoring for neurapraxia shown to have low sensitivity in predicting nerve deficit. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 13, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Could Diet Improve Outcomes in Glioblastoma?Could Diet Improve Outcomes in Glioblastoma?
Dr Alan Jacobs discusses an experimental study evaluating a high-fat, low-carbohydrate diet in mice with glioblastoma. Medscape Neurology (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 13, 2016 Category: Neurology Tags: Neurology & Neurosurgery Commentary Source Type: news

Vaccine Boosts Glioblastoma SurvivalVaccine Boosts Glioblastoma Survival
A novel combination of cytomegalovirus-targeted dendritic cell vaccine and tetanus preconditioning shows a significant increase in survival and improved immune response in glioblastoma. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 12, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Relapses Rebound in Patients With MS Stopping FingolimodRelapses Rebound in Patients With MS Stopping Fingolimod
As seen with natalizumab, a new study shows patients may experience rebound in relapses after stopping fingolimod. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 12, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Platelet Transfusion Harmful in ICH Patients on Antiplatelets Platelet Transfusion Harmful in ICH Patients on Antiplatelets
The first randomized trial of platelet therapy for patients with intracerebral hemorrhage taking antiplatelets gives a clear message not to pursue such treatment. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 12, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

MS Drug Linked to Colorectal Cancer RiskMS Drug Linked to Colorectal Cancer Risk
Despite its cardiotoxicity -- and now possibly colorectal cancer risk -- mitoxantrone might still be an appropriate therapy in carefully selected patients, researchers say. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 12, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Symptom Duration Matters in Degenerative Cervical MyelopathySymptom Duration Matters in Degenerative Cervical Myelopathy
Patients treated with decompressive surgery within 4 months of symptom presentation show improved outcomes for degenerative cervical myelopathy. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 11, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

ENCHANTED: Low-Dose tPA Now a Viable Option in Stroke?ENCHANTED: Low-Dose tPA Now a Viable Option in Stroke?
A new randomized trial has shown improved safety with a lower dose of tPA in stroke, but efficacy results were mixed. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 11, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Pesticides, Other Toxins Again Linked to Increased ALS Pesticides, Other Toxins Again Linked to Increased ALS
New study results reinforce previous suggestions that environmental exposure to pollutants, as well as a history of service in the armed forces, affects risk for amyotrophic lateral sclerosis. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 11, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

'Weekend Effect' in Hospital Deaths Is Oversimplified'Weekend Effect' in Hospital Deaths Is Oversimplified
Care is inconsistent for patients with acute stroke across week and time of day, not just weekends, according to one study. Another found no link between weekend staffing and patient mortality. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 11, 2016 Category: Neurology Tags: Internal Medicine News Source Type: news

IPD Reoperation Rates Still Hamper Benefit in Spinal StenosisIPD Reoperation Rates Still Hamper Benefit in Spinal Stenosis
The latest randomized trial again shows similar outcomes to surgery with a percutaneous interspinous process device in patients with lumbar spinal stenosis, but with increased reintervention. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 10, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Parkinson's Cell Transplant Shows Good Reinnervation at 24 YearsParkinson's Cell Transplant Shows Good Reinnervation at 24 Years
A postmortem report showing transplanted dopaminergic cells survived for almost a quarter of a century provides hope for future stem cell therapy, researchers say. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 10, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Prenatal Vitamin D and Risk for Multiple SclerosisPrenatal Vitamin D and Risk for Multiple Sclerosis
Dr Barclay discusses a study from Finland evaluating the risk for multiple sclerosis among children born to mothers with insufficient prenatal vitamin D levels. Medscape Neurology (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 10, 2016 Category: Neurology Tags: Neurology & Neurosurgery Viewpoint Source Type: news

BRAF Inhibitor Improves Radiosurgery Outcomes in MelanomaBRAF Inhibitor Improves Radiosurgery Outcomes in Melanoma
BRAF-carrying patients with melanoma and brain metastases treated with BRAF inhibitors and SRS show improved survival, but timing of treatment matters. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 10, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

FDA Panel Votes for IR Opioid but Without Abuse LabelingFDA Panel Votes for IR Opioid but Without Abuse Labeling
Despite the drug company's presentations, FDA advisory committee members didn't find enough evidence to recommend abuse-deterrent labeling for the new immediate-release product. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 9, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

No Increased Toxicity Seen With TKI, Stereotactic Radiosurgery No Increased Toxicity Seen With TKI, Stereotactic Radiosurgery
TKIs used as radiosensitizers are believed to offer a synergistic effect with radiosurgery in treatment of spine metastases with renal cell carcinoma. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 6, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

FDA Panel: Physician Opioid Training Should Be MandatoryFDA Panel: Physician Opioid Training Should Be Mandatory
A 2-day FDA advisory panel meeting this week focused on ways to modify the opioid analgesic Risk Evaluation and Mitigation Strategies. Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - May 6, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news