BOHEMIA: Broad One Health Endectocide-based Malaria Intervention in Africa —a phase III cluster-randomized, open-label, clinical trial to study the safety and efficacy of ivermectin mass drug administration to reduce malaria transmission in two African settings
DiscussionThe second site for the implementation of this protocol has changed from Tanzania to Kenya. This summary presents the Mozambique-specific protocol while the updated master protocol and the adapted Kenya-specific protocol undergo national approval in Kenya. BOHEMIA will be the first large-scale trial evaluating the impact of ivermectin-only mass drug administration to humans or humans and cattle on local malaria transmissionTrial registrationClinicalTrials.govNCT04966702. Registered on July 19, 2021.Pan African Clinical Trials Registry PACTR202106695877303. (Source: Trials)
Source: Trials - February 21, 2023 Category: Research Source Type: clinical trials
A Pan-TB Regimen Targeting Host and Microbe
Condition: Tuberculosis Interventions: Drug: Sutezolid; Drug: N-acetyl cysteine; Drug: Pretomanid; Drug: Bedaquiline; Combination Product: Rifafour Sponsors: The Aurum Institute NPC; Ludwig-Maximilians - University of Munich; Stichting Katholieke Universiteit; Wits Health Consortium (Pty) Ltd; Instituto Nacional de Saúde, Mozambique; National Institute for Medical Research, Tanzania; University of Stellenbos ch; Sequella, Inc.; Global Alliance for TB Drug Development Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 17, 2023 Category: Research Source Type: clinical trials
