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Pharmacokinetic Drug-drug Interaction Study of Encorafenib and Binimetinib on Probe Drugs in Patients With BRAF V600-mutant Melanoma or Other Advanced Solid Tumors
Conditions:   Advanced Solid Tumors;   Metastatic Melanoma Interventions:   Drug: losartan;   Drug: dextromethorphan;   Drug: caffeine;   Drug: omeprazole;   Drug: midazolam;   Drug: rosuvastatin;   Drug: bupropion immediate release (IR);   Drug: encorafenib;   Drug: binimetinib;   Drug: modafinil Sponsors:   Array BioPharma;   Pierre Fabre Laboratories Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 6, 2019 Category: Research Source Type: clinical trials

Modafinil Versus Amphetamines for the Treatment of Narcolepsy Type 2 and Idiopathic Hypersomnia
Conditions:   Idiopathic Hypersomnia;   Narcolepsy Without Cataplexy Interventions:   Drug: Modafinil;   Drug: Amphetamine-Dextroamphetamine Sponsors:   Emory University;   American Academy of Sleep Medicine Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 11, 2018 Category: Research Source Type: clinical trials