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ATP and P2X3 Receptor in Chronic Cough
Condition:   Cough Interventions:   Device: Adenosine triphosphate (ATP) solution inhalation from nebuliser;   Diagnostic Test: Inhalational challenge with increasing concentrations of capsaicin solutions;   Device: Recording of Cough Count and frequency using the Hyfe Cough Monitor;   Procedure: Collection of exhaled breath co ndensate;   Diagnostic Test: Continuous laryngoscopic examination;   Diagnostic Test: Sputum induction;   Diagnostic Test: Spirometric measurements;   Diagnostic Test: Blood sample collection Sponsors:   Imperial College London;   Merck Sharp & Dohme LLC Not yet recruiting...
Source: ClinicalTrials.gov - February 6, 2023 Category: Research Source Type: clinical trials

Mechanisms Preventing Pharyngeal Reflux
Condition:   GERD Interventions:   Diagnostic Test: Concurrent manometry/impedance/pH with video pharyngo-laryngoscopy;   Diagnostic Test: Slow and rapid intra-esophageal infusion Sponsor:   Medical College of Wisconsin Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2023 Category: Research Source Type: clinical trials