Endovascular management of penetrating and non-penetrating aortic injury.
Abstract Aortic trauma is a devastating injury often associated with significant polytrauma. Penetrating injury of the aorta is highly lethal and therefore rarely encountered in the hospital setting. The management of blunt trauma of the aorta has changed significantly over the past decade, principally due to improved imaging technology and the development of endovascular therapy. The most common site of injury is the proximal descending thoracic aorta. The degree of aortic wall injury guides the indication for therapy, while a combination of the degree of injury and the extent of co-morbid injuries drives the tim...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - September 19, 2018 Category: Surgery Authors: Chou EL, Twerdahl EH, Eagleton MJ Tags: Vasa Source Type: research

Antiphospholipid syndrome - an update.
Abstract Antiphospholipid syndrome (APS) is an autoantibody-mediated acquired thrombophilia. It is characterized by the presence of antiphospholipid antibodies (APL) that are directed against phospholipid-binding plasma proteins, such as beta-2-glycoprotein I (b2GPI). Its main manifestations are recurrent vascular thromboses (so-called "thrombotic APS") and pregnancy complications ("obstetric APS"). According to the current consensus criteria, a persistently positive functional lupus anticoagulant (LA) assay and/or the presence of anti-b2GPI and/or anti-cardiolipin antibodies, together with cli...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - September 12, 2018 Category: Surgery Authors: Linnemann B Tags: Vasa Source Type: research

Thromboembolic disease in females and males aged 10 to 39 years in Germany.
CONCLUSIONS: The presented data show higher hospitalization rates for females in the age group 10 to 39 years for different venous thrombosis but not for MI and ES. PMID: 30200845 [PubMed - as supplied by publisher] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - September 11, 2018 Category: Surgery Authors: von Beckerath O, Santosa F, Waldhausen R, Moerchel C, Kröger K Tags: Vasa Source Type: research

Comparison of urine and serum neutrophil gelatinase-associated lipocalin after open and endovascular thoraco-abdominal aortic surgery and their meaning as indicators of acute kidney injury.
In this study, the course of NGAL was observed and differences of serum- (sNGAL) and urine-NGAL (uNGAL) levels following TAAA repair, especially with regard to AKI, were evaluated. PATIENTS AND METHODS: In this retrospective single centre study, 52 patients (mean age 64.5 years, [43-85 years]), including 39 (75 %) men, were enrolled (2014-2015, 13.2 months mean follow-up). Levels of sNGAL and uNGAL were measured perioperatively for 48 hours on intensive care unit. Twenty-three patients were treated by endovascular and 29 by open TAAA-repair. RESULTS: Logistic regression revealed an increase in NGAL (sNGAL p = 0.0...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - September 10, 2018 Category: Surgery Authors: Gombert A, Martin L, Foldenauer AC, Krajewski C, Greiner A, Kotelis D, Stoppe C, Marx G, Grommes J, Schuerholz T, Jacobs MJ, Kalder J Tags: Vasa Source Type: research

Impact of diabetes mellitus on early outcome of carotid endarterectomy.
Abstract BACKGROUND: Diabetes mellitus increases the risk of ischaemic stroke in the general population but its impact on early outcome after the carotid endarterectomy (CEA) is controversial with conflicting results. PATIENTS AND METHODS: This prospective study includes 902 consecutive CEAs. Patients were divided into non-diabetic and diabetic groups and subsequently analysed. Early outcomes in terms of 30-day stroke and death rates were then analysed and compared. RESULTS: There were 606 non-diabetic patients. Among 296 diabetic patients, 83 were insulin-dependent. The cumulative TIA/stroke rate was st...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - September 7, 2018 Category: Surgery Authors: Dimic A, Markovic M, Vasic D, Dragas M, Zlatanovic P, Mitrovic A, Davidovic L Tags: Vasa Source Type: research

Ultrasound-guided thrombin injection for treatment of femoral artery pseudoaneurysm with concomitant AV-fistula - a retrospective single centre experience.
t I Abstract BACKGROUND: Increasing volume of complex percutaneous endovascular procedures in highly anticoagulated patients generate a not negligible percentage of femoral pseudoaneurysms (PSA) with concomitant arteriovenous fistulas (AVF). While ultrasound-guided thrombin injection (UGTI) is the therapy of choice for PSA, concomitant AVF is regarded as a contraindication for UGTI, as venous thromboembolism is feared. In this retrospective, register-based cohort study, we report on and evaluate the use of UGTI for the treatment of PSA with AFV. PATIENTS AND METHODS: All patients (n = 523), who underwent UGTI...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - September 3, 2018 Category: Surgery Authors: Steppich B, Schürmann F, Bruskina O, Hadamitzky M, Kastrati A, Schunkert H, Fusaro M, Ott I Tags: Vasa Source Type: research

Placement of closed-cell designed venous stents in a mixed cohort of patients with chronic venous outflow obstructions - short-term safety, patency, and clinical outcomes.
CONCLUSIONS: The Vici Venous Stent® placed in the ilio-femoral vein segment in patients with symptomatic VOO revealed no safety issues, had excellent primary patency and substantial symptom improvement. Long-term studies are needed to evaluate the durability of this stenting procedure. PMID: 30175948 [PubMed - as supplied by publisher] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - September 3, 2018 Category: Surgery Authors: Lichtenberg M, Breuckmann F, Stahlhoff WF, Neglén P, de Graaf R Tags: Vasa Source Type: research

Large left innominate vein aneurysm presenting as an anterior mediastinal tumour in a young female.
We report a rare case of large innominate vein aneurysm in a young women clinically presenting with persistent dry cough and retrosternal pressure. Chest X-ray showed a mediastinal widening leading to thoracic computed tomography, MRI, and phlebography. Initial conservative treatment with regular follow-up was performed. Upon aneurysm growth and recurrent pulmonary infection we decided to surgically resect the aneurysm via a minimally invasive approach. PMID: 30141380 [PubMed - as supplied by publisher] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - August 24, 2018 Category: Surgery Authors: Lohrenz C, Rückner D, Wintzer O, Gross-Fengels W, Meierling S Tags: Vasa Source Type: research

Rationale and methods of the IDOMENEO health outcomes of the peripheral arterial disease revascularisation study in the GermanVasc registry.
DISCUSSION: It remains unclear if results from RCT can reflect daily treatment practice. Furthermore, great costs and complexity make it challenging to accomplish high quality randomized trials in PAD treatment. Prospective registry-based studies to collect real-world evidence can help to overcome these limitations. PMID: 30113269 [PubMed - as supplied by publisher] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - August 16, 2018 Category: Surgery Authors: Debus ES, Kriston L, Schwaneberg T, Hischke S, Rieß HC, Härter M, Marschall U, Federrath H, Behrendt CA Tags: Vasa Source Type: research

Heterogeneity of Doppler waveform description is decreased with the use of a dedicated classification.
ndi V Abstract BACKGROUND: The analysis of Doppler ultrasound waveforms (DW) provides a method for detecting and evaluating arterial stenosis in the lower limb arteries but no recommendation exists on how to describe the DWs. Aims of this study were to assess the heterogeneity of the description of DWs among vascular residents and the impact of the use of a 4-item classification. METHODS: Thirty different DWs were presented to residents using Microsoft PowerPoint® slides. They were invited to describe the 30 DWs before and after the presentation of a 4-item classification (triphasic, biphasic, monophasic,...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - August 7, 2018 Category: Surgery Authors: Omarjee L, Stivalet O, Hoffmann C, Scissons R, Bressollette L, Mahé G, Jaquinandi V Tags: Vasa Source Type: research

Atherosclerosis knowledge - diagnosis and management in primary care.
jee L Abstract BACKGROUND: Atherosclerosis is the leading cause of death worldwide. Ischaemic stroke, coronary heart disease (CHD), and peripheral artery disease (PAD) are different forms of atherosclerotic disease. Knowledge among general practitioners (GPs) about the three main locations of atherosclerosis has never been conjointly explored in a single study. The aim of this survey was to compare GP awareness on the subject of these three different clinical presentations. MATERIALS AND METHODS: Between February 2017 and May 2017, a self-administered survey was emailed to 18,500 French GPs. The questionnaire...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - July 26, 2018 Category: Surgery Authors: Charasson M, Mahé G, Le Brun C, Jaquinandi V, Rossignol E, Le Faucheur A, Omarjee L Tags: Vasa Source Type: research

Staged ultrasound-guided liposuction for hidden arteriovenous fistulas in obese patients.
CONCLUSIONS: USGL is a method that can be learned easily, is minimally invasive, seems to be safe, and requires only short operation times. PMID: 30022718 [PubMed - as supplied by publisher] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - July 19, 2018 Category: Surgery Authors: Cs Nagy G, Verwiebe R, Wunsch M Tags: Vasa Source Type: research

Sex hormones and venous thromboembolism - from contraception to hormone replacement therapy.
Abstract The use of sex hormones such as combined oral contraceptives (COC) or hormone replacement therapy (HRT) increases the risk for venous thromboembolism (VTE) considerably, especially in patients with an increased intrinsic risk for thromboembolic complications. Despite public and media attention and increasing scientific evidence, prescription patterns seem to be hard to change. It is well recognized that the patient's baseline risk is the most relevant factor in the absolute risk for developing VTE. The relative risk increase associated with sex hormones, depends on the type and dosage of hormones, the rou...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - July 16, 2018 Category: Surgery Authors: Beyer-Westendorf J, Bauersachs R, Hach-Wunderle V, Zotz RB, Rott H Tags: Vasa Source Type: research

Stent fractures after common femoral artery bail-out stenting due to suture device failure in TAVR.
CONCLUSIONS: The implantation of a covered stent graft is highly effective and safe to control vascular access site-related complications after TAVR. Stent/strut fractures in the flexible segment of the common femoral artery may occur, as consequently verified by X-ray visualization, but show no impairment on flow or clinical parameters after six to 12 months. PMID: 29952252 [PubMed - as supplied by publisher] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - June 28, 2018 Category: Surgery Authors: Veulemans V, Afzal S, Ledwig P, Heiss C, Busch L, Sansone R, Soetemann DB, Maier O, Kleinebrecht L, Kelm M, Zeus T, Hellhammer K Tags: Vasa Source Type: research

Symptomatic carotid stenosis and ipsilateral carotid body tumor.
We report an unusual combination of a symptomatic carotid stenosis and ipsilateral carotid body tumor. This patient was successfully treated with simultaneous carotid endarterectomy and tumor resection. Following, the unique challenges and technique are discussed. PMID: 29911935 [PubMed - as supplied by publisher] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - June 18, 2018 Category: Surgery Authors: Shah SK, Levine S, O'Leary J, Belkin M Tags: Vasa Source Type: research

High iliac calcium score is associated with increased severity and complexity of peripheral arterial disease and predicts global atherosclerotic burden.
Abstract BACKGROUND: The role of vascular calcifications in iliac arteries for predicting global atherosclerotic burden in still unknown. The aim of this study was to investigate whether iliac calcium score (ICS), a new computed tomographic angiography (CTA) derived biomarker of vascular calcification, can predict the severity and complexity of peripheral arterial disease (PAD) as well as the global atherosclerotic burden. PATIENTS AND METHODS: This was a single centre, non-randomized, observational prospective study on 84 consecutive patients with symptomatic peripheral arterial disease, undergoing periphera...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - June 13, 2018 Category: Surgery Authors: Jeremias Z, Rat N, Benedek I, Rapolti E, Ratiu M, Muresan A, Benedek T Tags: Vasa Source Type: research

Treating great and small saphenous vein insufficiency with histoacryl in patients with symptomatic varicose veins and increased risk of surgery.
CONCLUSIONS: We demonstrated that treating insufficient saphenous veins with modified histoacryl application brought a relief from symptoms of venous insufficiency and that the efficiency of this technique is comparable to commonly used methods. PMID: 29890917 [PubMed - as supplied by publisher] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - June 12, 2018 Category: Surgery Authors: Novotný K, Roček M, Pádr R, Pavlík R, Polovinčák M, Adla T, Zimolová P, Choi-Širůčková J, Weis M, Jirát S, Rohn V Tags: Vasa Source Type: research

Indicators of outcome quality in peripheral arterial disease revascularisations - a Delphi expert consensus.
CONCLUSIONS: This Delphi approach of vascular experts identified three indicators as highly relevant and clinically practicable to be recommended as indicators of outcome quality in invasive PAD treatment. Among others, these consented items may help in harmonising future studies and quality benchmarking increasing their comparability, validity, and efficiency. PMID: 29856270 [PubMed - as supplied by publisher] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - June 1, 2018 Category: Surgery Authors: Rieß HC, Debus ES, Schwaneberg T, Hischke S, Maier J, Bublitz M, Kriston L, Härter M, Marschall U, Zeller T, Schellong SM, Behrendt CA Tags: Vasa Source Type: research

The influence of age on valve disease in patients with varicose veins analysed by transmission electron microscopy and stereology.
CONCLUSIONS: The ultrastructural morphology of the venous valves in chronic venous disorders may not depend on age in patients presenting with C2 disease. This conclusion may or may not apply to all C classes as we investigated a homogenous group of patients with C2 limbs. PMID: 29808768 [PubMed - as supplied by publisher] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - May 29, 2018 Category: Surgery Authors: Mouton WG, Wagner MO, Haenni B, Mouton KT, Ochs M, Tschanz SA Tags: Vasa Source Type: research

Devastating cerebral Lipiodol ® embolization related to therapeutic lymphangiography for refractory chylothorax in a patient with Behçet's disease.
Devastating cerebral Lipiodol® embolization related to therapeutic lymphangiography for refractory chylothorax in a patient with Behçet's disease. Vasa. 2018 May 29;:1-3 Authors: Geeroms B, Demaerel P, Wauters J, Verschakelen J, Maleux G Abstract Onset of neurological symptoms early after intranodal lymphangiography can occur due to Lipiodol droplet migration through intrapulmonary lymphovenous communication. Patients with Behçet's disease may be at higher risk of developing this devastating complication. PMID: 29808774 [PubMed - as supplied by publisher] (Source: VASA. Zeitschr...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - May 29, 2018 Category: Surgery Authors: Geeroms B, Demaerel P, Wauters J, Verschakelen J, Maleux G Tags: Vasa Source Type: research

Incidence and risk factors of recurrent pain in acute aortic dissection and in-hospital mortality.
Abstract BACKGROUND: We investigated the prevalence of recurrent pain and its relationship with in-hospital mortality in acute aortic dissection (AAD). PATIENTS AND METHODS: Between 2011 and 2016, 234 AAD patients were selected. Recurrent pain was defined as a mean of VAS> 3, within 48 hours following hospital admission or before emergency operation. Patients with and without recurrent pain were divided into group I and group II, respectively into type A AAD and type B AAD patients. Our primary outcome was in-hospital mortality. RESULTS: The incidence of recurrent pain was 24.4 % in AAD patients. Inci...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - May 29, 2018 Category: Surgery Authors: Siti D, Abudesimu A, Ma X, Yang L, Ma X, Ma YT Tags: Vasa Source Type: research

State-of-the-art pulmonary arterial imaging - Part 1.
Abstract The pulmonary arteries are affected by a variety of congenital and acquired abnormalities. Multiple state-of-the art imaging modalities are available to evaluate these pulmonary arterial abnormalities, including computed tomography (CT), magnetic resonance imaging (MRI), echocardiography, nuclear medicine imaging and catheter pulmonary angiography. In part one of this two-part series on state-of-the art pulmonary arterial imaging, we review these imaging modalities, focusing particularly on CT and MRI. We also review the utility of these imaging modalities in the evaluation of pulmonary thromboembolism. ...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - May 28, 2018 Category: Surgery Authors: Tanabe Y, Landeras L, Ghandour A, Partovi S, Rajiah P Tags: Vasa Source Type: research

State-of-the-art pulmonary arterial imaging - Part 2.
Abstract Although pulmonary embolism is the most common abnormality of the pulmonary artery, there is a broad spectrum of other congenital and acquired pulmonary arterial abnormalities. Multiple imaging modalities are now available to evaluate these abnormalities of the pulmonary arteries. CT and MRI are the most commonly used cross-sectional imaging modalities that provide comprehensive information on several aspects of these abnormalities, including morphology, function, risk-stratification and therapy-monitoring. In this article, we review the role of state-of-the-art pulmonary arterial imaging in the evaluatio...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - May 28, 2018 Category: Surgery Authors: Goerne H, Chaturvedi A, Partovi S, Rajiah P Tags: Vasa Source Type: research

Management of the left subclavian artery during TEVAR - complications and mid-term follow-up.
CONCLUSIONS: The study shows that performing TEVAR without primary revascularization of the LSA was justifiable in our cohort. An important risk factor of developing cerebral ischemia seems to be insufficient collateralization through the circle of Willis. PMID: 29788799 [PubMed - as supplied by publisher] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - May 23, 2018 Category: Surgery Authors: Youssef A, Ghazy T, Kersting S, Leip JL, Hoffmann RT, Kappert U, Matschke K, Weiss N, Mahlmann A Tags: Vasa Source Type: research

Gender differences in abdominal aortic aneurysm therapy - a systematic review.
This article analyses if and to what extent gender differences exist in abdominal aortic aneurysm (AAA) therapy. For this purpose Medline (PubMed) was searched from January 1999 to January 2018. Keywords were: "abdominal aortic aneurysm", "gender", "prevalence", "EVAR", and "open surgery of abdominal aortic aneurysm". Regardless of open or endovascular treatment of abdominal aortic aneurysms, women have a higher rate of complications and longer hospitalizations compared to men. The majority of studies showed that women have a lower survival rate for surgical and endovascula...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - May 7, 2018 Category: Surgery Authors: Stoberock K, Kölbel T, Atlihan G, Debus ES, Tsilimparis N, Larena-Avellaneda A, Behrendt CA, Wipper S Tags: Vasa Source Type: research

Risk allele of gene variant rs6584389 is associated with increased intima-media thickness in patients with type 2 diabetes.
CONCLUSIONS: Gene variant rs6584389 A>C near to PAX2 gene was associated with increased carotid IMT in patients with type 2 diabetes independently of the other main risk factors for atherosclerosis. PMID: 29671694 [PubMed - as supplied by publisher] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - April 19, 2018 Category: Surgery Authors: Kozarova M, Malachovska Z, Zidzik J, Javorsky M, Demkova K, Habalova V, Tkac I Tags: Vasa Source Type: research

Cathepsin S is associated with degradation of collagen I in abdominal aortic aneurysm.
k J Abstract BACKGROUND: Cathepsins have been described in the pathogenesis of abdominal aortic aneurysm (AAA), their exact role, especially in collagen degradation, is still unclear. The aim of the present study was therefore to analyse relevant cathepsins in human AAA tissue samples in relation to collagen I, III, and their degradation products. MATERIALS AND METHODS: Samples from 37 AAA patients obtained from elective open surgical repair and eight healthy non-aneurysmatic aortas from kidney donors were included. Expression of cathepsins B, D, K, L, S, cystatin C, collagen I and III, their degraded product...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - April 6, 2018 Category: Surgery Authors: Klaus V, Schmies F, Reeps C, Trenner M, Geisbüsch S, Lohoefer F, Eckstein HH, Pelisek J Tags: Vasa Source Type: research

Safety of percutaneous axillary artery access with a suture-mediated closing device for parallel endograft aortic procedures - a retrospective pilot study.
CONCLUSIONS: Percutaneous ultrasound-guided infraclavicular axillary artery access with preclosing modification seems feasible and safe. The access related complication rate is low and complications can potentially be managed by endovascular means. PMID: 29583101 [PubMed - as supplied by publisher] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - March 27, 2018 Category: Surgery Authors: Puippe GD, Kobe A, Rancic Z, Pfiffner R, Lachat M, Pfammatter T Tags: Vasa Source Type: research

Endobag separation - an ominous sign after endovascular aneurysm sealing with the Nellix device.
Abstract Our report aims to alert physicians performing endovascular aneurysm sealing with the Nellix endoprosthesis to the risk of rupture when endobag separation is noticed on computed tomography. Endobag separation when observed with acute presentation of abdominal pain is an indicator of imminent rupture and prompt interventional treatment should be undertaken. PMID: 29575981 [PubMed - as supplied by publisher] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - March 26, 2018 Category: Surgery Authors: Tasleem S, Badri H, Ranjeet N, Antoniou GA Tags: Vasa Source Type: research

Microarray analysis for delineating the gene expression in biopsies of gastrocnemius muscle of patients with chronic critical limb ischaemia compared with non-ischaemic controls.
CONCLUSIONS: Gene expression profiles in biopsies of gastrocnemius muscle in patients with chronic critical limb ischaemia showed an increase in pro-survival factors, extracellular matrix protein deposition, and impaired proliferation, compared with non-ischaemic controls. Further studies are required to analyse the endogenous repair mechanism. PMID: 29557735 [PubMed - as supplied by publisher] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - March 20, 2018 Category: Surgery Authors: Freund D, Brilloff S, Ghazy T, Kirschner S, Gäbel G, Hinterseher I, Weiss N, Mahlmann A Tags: Vasa Source Type: research

Standards for recanalisation of chronic venous outflow obstructions.
Abstract Postthrombotic syndrome (PTS) is the most common complication after iliofemoral deep vein thrombosis. It reduces quality of life and increases deep vein thrombosis (DVT)-related costs. The clinical symptoms and severity of PTS may vary; the most common symptoms include edema, pain (venous claudication), hyperpigmentation, lipodermatosclerosis, and ulceration. PTS is based on the principle of outflow obstruction, which may be caused by venous hypertension and may lead to valvular damage and venous reflux or insufficiency. Recent technical developments and new stent techniques now allow recanalisation of ev...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - March 8, 2018 Category: Surgery Authors: Lichtenberg M, de Graaf R, Erbel C Tags: Vasa Source Type: research

Endovascular treatment of post-thrombotic and non-thrombotic iliofemoral venous outflow obstructions with self-expanding nitinol stents.
Abstract BACKGROUND: The aim of the study was to investigate venous patency and clinical outcomes for endovascular treatment of iliofemoral venous obstruction in patients with post-thrombotic syndrome (PTS) and non-thrombotic iliac vein lesion (NIVL) with dedicated self-expanding nitinol stents. PATIENTS AND METHODS: Data were collected from the prospective Swiss Venous Stent Registry, enrolling consecutive patients with a standardized follow-up procedure since January 2008. Patency was evaluated by duplex sonography and clinical outcome by various scores including the Villalta score at baseline, three, six, ...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - March 7, 2018 Category: Surgery Authors: Stuck AK, Reich T, Engelberger RP, Sebastian T, Kucher N Tags: Vasa Source Type: research

Hybrid treatment of multilevel revascularization in patients with peripheral arterial disease - a multi-centre study in Korea.
Abstract BACKGROUND: Endovascular treatment is an alternative first-line management for peripheral artery disease (PAD). Hybrid treatment (HT) is defined as a combined treatment for patients with PAD using endovascular and open surgery, simultaneously performed in an operating room. The results of HT are reportedly good for multilevel revascularization (MR) in patients with chronic limb ischaemia, and even in older high-risk patients. The goal of this study was to examine the clinical and haemodynamic outcomes of HT in patients who need MR. PATIENTS AND METHODS: Nine university hospitals in Korea participated...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - February 27, 2018 Category: Surgery Authors: Lee SC, Joh JH, Chang JH, Kim HK, Kim JY, Park K, Hong KC, Byun SJ, Lee TS, Jung HJ, Lee SS Tags: Vasa Source Type: research

Deep vein thrombosis and properties of the arterial wall.
on; P Abstract BACKGROUND: Deep vein thrombosis (DVT) affects more than one out of 1,000 people every year, of which 50 % develop post-thrombotic syndrome (PTS). Studies indicated that patients with DVT have deteriorated arterial wall function, while less is known about the association with PTS. We therefore investigated this relationship further. PATIENTS AND METHODS: A total of 120 patients treated for DVT of the lower extremity and a control group of 40 subjects without DVT were included. We assessed the presence of PTS using the Villalta scale. Flow-mediated dilation (FMD) and nitroglycerin-mediated dilat...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - February 27, 2018 Category: Surgery Authors: Jeraj L, Spirkoska A, Ježovnik MK, Poredoš P Tags: Vasa Source Type: research

Effect of oral nut supplementation on endothelium-dependent vasodilation - a meta-analysis.
CONCLUSIONS: Supplementation of nuts significantly improves the vascular endothelial function without affecting endothelium-independent vasodilatation. PMID: 29478408 [PubMed - as supplied by publisher] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - February 26, 2018 Category: Surgery Authors: Huang Y, Zheng S, Wang T, Yang X, Luo Q, Li H Tags: Vasa Source Type: research

Home-based exercise for elderly patients with intermittent claudication limited by osteoarticular disorders - feasibility and effectiveness of a low-intensity programme.
CONCLUSIONS: Equally satisfactory rehabilitative outcomes were observed in elderly patients with claudication limited by ODs who completed a well-tolerated, low-impact structured exercise programme. PMID: 29463192 [PubMed - as supplied by publisher] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - February 21, 2018 Category: Surgery Authors: Lamberti N, Straudi S, Lissia E, Cavazzini L, Buja S, Manfredini R, Basaglia N, Manfredini F Tags: Vasa Source Type: research

Do not underestimate the femoral pseudoaneurysm.
Abstract In addition to haematoma and arteriovenous fistula, the iatrogenic pseudoaneurysm is a common complication of vascular access that is caused by a perforation in the arterial wall. Iatrogenic pseudoaneurysms can progress in size and lead to rupture and active bleeding. Over the previous few decades, therapeutic methods have evolved from surgical repair to less invasive options, such as ultrasound-guided compression therapy (UGCT) and ultrasound-guided thrombin injection (UGTI). This paper presents an overview of the diagnostic and treatment modalities used in femoral pseudoaneurysms as well as a comprehens...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - February 14, 2018 Category: Surgery Authors: Stolt M, Braun-Dullaeus R, Herold J Tags: Vasa Source Type: research

PCSK9 inhibition for LDL lowering and beyond - implications for patients with peripheral artery disease.
Abstract Low-density lipoprotein cholesterol (LDL-C) has been proven to be a causal factor of atherosclerosis and, along with other triggers like inflammation, the most frequent reason for peripheral arterial disease. Moreover, a linear correlation between LDL-C concentration and cardiovascular outcome in high-risk patients could be established during the past century. After the development of statins, numerous randomized trials have shown the superiority for LDL-C reduction and hence the decrease in cardiovascular outcomes including mortality. Over the past decades it became evident that more intense LDL-C loweri...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - February 7, 2018 Category: Surgery Authors: Gebauer K, Reinecke H Tags: Vasa Source Type: research

Loco-regional versus general anaesthesia for elective endovascular aneurysm repair - results of a cohort study and a meta-analysis.
Abstract BACKGROUND: The aim of this study was to investigate whether patients undergoing elective endovascular aneurysm repair (EVAR) with loco-regional anaesthetic techniques have better outcomes than those treated with general anaesthesia (GA). PATIENTS AND METHODS: We retrospectively evaluated outcomes of EVAR performed with regional anaesthesia (RA) or GA over a five-year period. Furthermore, we searched electronic bibliographic sources (MEDLINE, EMBASE, CINAHL, and CENTRAL) to identify studies comparing different anaesthetic methods in EVAR. We defined perioperative mortality and morbidity as well as le...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - February 5, 2018 Category: Surgery Authors: Hajibandeh S, Hajibandeh S, Adasonla K, Antoniou SA, Barrie J, Madan M, Antoniou GA Tags: Vasa Source Type: research

Development and validation of the Patient Benefit Index for peripheral arterial disease.
Abstract BACKGROUND: The aim of this study was to develop and validate a specific Patient Benefit Index (PBI) version for the treatment of peripheral arterial disease (PAD). PATIENTS AND METHODS: A non-interventional longitudinal development study was conducted. The first phase comprised a qualitative pre-study with n = 50 patients, in which the PBI was adapted for peripheral arterial disease. The resulting Patient Benefit Index for peripheral arterial disease (PBI-PAD) was validated in the second phase at two points of measurement. The total PBI-PAD score was calculated by weighting item-wise the achievement...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - January 25, 2018 Category: Surgery Authors: Zander N, Demirel EB, Augustin M, Sommer R, Debus ES, Breuer P, Blome C Tags: Vasa Source Type: research

Haemostaseological complication management in caval and iliac venous stenting.
Abstract Antiplatelet and anticoagulation therapy after venous stenting is still not standardized, data from randomized-controlled trials are missing. Rare prothrombotic disorders and nonresponsiveness to drugs must be taken into account. This case report demonstrates successful haemostaselogical complication management in recurrent rethromboses due to underlying clopidogrel resistance and low responsiveness to anticoagulation with dabigatran after endovascular stent reconstruction of chronic pelvic and caval vein occlusion in a patient with severe postthrombotic syndrome. PMID: 29336234 [PubMed - as supplied...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - January 16, 2018 Category: Surgery Authors: Kohler C, Fuss T, Schweizer R, Baumgartner I, Kucher N, Schindewolf M Tags: Vasa Source Type: research

Mortality after endovascular treatment of infrarenal abdominal aortic aneurysms - the newer the better?
Abstract Although endovascular repair of infrarenal abdominal aortic aneurysms (EVAR) presents a delicate alternative treatment for abdominal aortic aneurysms (AAA) with lower perioperative mortality, its long-term efficacy remains a matter of concern. The purpose of this study was to evaluate the currently reported mortality evidence after EVAR and to examine the possible effect of aneurysm status and the study period on mortality rates. The PubMed and Cochrane bibliographical databases were thoroughly searched for studies reporting on more than 1 000 patients with non-ruptured or ruptured infrarenal AAA, treated...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - January 15, 2018 Category: Surgery Authors: Tzani A, Doulamis IP, Katsaros I, Martinou E, Schizas D, Economopoulos KP Tags: Vasa Source Type: research

Management of cancer-associated venous thromboembolism - a case-based practical approach.
Abstract In patients with solid tumours or haematological malignancies, venous thromboembolism (VTE) is a leading cause of death and significantly contributes to morbidity and healthcare resource utilization. Current practice guidelines recommend long-term anticoagulation with low-molecular-weight heparin (LMWH) as the treatment of choice for cancer-associated VTE, based on clinical trial data showing an overall improved safety and efficacy profile of LMWH compared to vitamin K antagonists. However, several open questions remain, e. g. with regard to the intensity and duration of LMWH therapy; moreover, recent rea...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - January 12, 2018 Category: Surgery Authors: Voigtlaender M, Langer F Tags: Vasa Source Type: research

Platelet-to-lymphocyte ratio, neutrophil-to-lymphocyte ratio, and platelet indices in patients with acute deep vein thrombosis.
Abstract BACKGROUND: Inflammation is associated with an increased risk of thrombotic events and complete blood count (CBC) is an easily measured test. The purpose of this study was to evaluate the value of CBC relative parameters including mean platelet volume (MPV), platelet-to-lymphocyte ratio (PLR), mean platelet volume-to-lymphocyte ratio (MPVLR), and neutrophil-to-lymphocyte ratio (NLR) for patients with acute deep vein thrombosis (DVT). PATIENTS AND METHODS: A total of 115 patients with unprovoked DVT of the lower extremities and 105 controls were recruited in this study. Blood samples were drawn from a...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - January 12, 2018 Category: Surgery Authors: Ming L, Jiang Z, Ma J, Wang Q, Wu F, Ping J Tags: Vasa Source Type: research

Osteoprotegerin concentration is associated with the presence and severity of peripheral arterial disease in type 2 diabetes mellitus.
, Javorský M, Tkáč I Abstract BACKGROUND: Osteoprotegerin plays a role in the development of several bone diseases. In addition, osteoprotegerin may contribute to the development of vascular disease. Little is known about the association between serum osteoprotegerin levels and the presence or severity of peripheral arterial disease (PAD). The aim of this study was to examine the association between serum osteoprotegerin levels and both the presence as well as the severity of lower extremity arterial disease in patients with type 2 diabetes (T2DM). PATIENTS AND METHODS: The study included 165 c...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - January 9, 2018 Category: Surgery Authors: Demková K, Kozárová M, Malachovská Z, Javorský M, Tkáč I Tags: Vasa Source Type: research

Erythromelalgia.
Abstract Erythromelalgia is a rare syndrome characterized by the intermittent or, less commonly, by the permanent occurrence of extremely painful hyperperfused skin areas mainly located in the distal extremities. Primary erythromelalgia is nowadays considered to be a genetically determined neuropathic disorder affecting SCN9A, SCN10A, and SCN11A coding for NaV1.7, NaV1.8, and NaV1.9 neuronal sodium channels. Secondary forms might be associated with myeloproliferative disorders, connective tissue disease, cancer, infections, and poisoning. Between the pain episodes, the affected skin areas are usually asymptomatic,...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - January 4, 2018 Category: Surgery Authors: Klein-Weigel PF, Volz TS, Richter JG Tags: Vasa Source Type: research

Effects of atmospheric pressure dynamics on abdominal aortic aneurysm rupture onset.
CONCLUSIONS: Although these pressure differences are very small, higher AP values over longer periods of time as well as greater variability are associated with RAAA. The exact mechanism behind this association remains unclear. The postulation that low AP may precipitate RAAA based on the Laplace law should be discarded. PMID: 29299980 [PubMed - as supplied by publisher] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - January 4, 2018 Category: Surgery Authors: Opacic D, Ilic N, Sladojevic M, Schönleitner P, Markovic D, Kostic D, Davidovic L Tags: Vasa Source Type: research

Drug coated ballons for femoro-popliteal interventions.
PMID: 29281955 [PubMed - in process] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - December 30, 2017 Category: Surgery Authors: Tamburrini L, Vosseler M, Espinola-Klein C Tags: Vasa Source Type: research

Do we have to change therapeutic considerations in peripheral arterial disease?
PMID: 29281956 [PubMed - in process] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - December 30, 2017 Category: Surgery Authors: Berent R, Sinzinger H Tags: Vasa Source Type: research

Incidental finding of an absent left common carotid artery.
We describe a case of a young woman evaluated for Raynaud's phenomenon in whom an extremely rare variation, the absence of the left common carotid artery, was incidentally detected as an isolated finding. The detection of vascular anomalies may be important for future endovascular or surgical interventions. PMID: 29271704 [PubMed - as supplied by publisher] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - December 22, 2017 Category: Surgery Authors: Noflatscher M, Luger AK, Frank R, Glodny B, Gruber J, Marschang P Tags: Vasa Source Type: research