Relapses in three patients with Takayasu arteritis under tocilizumab treatment detected by contrast enhanced ultrasound.
t C Abstract Takayasu arteritis (TA) is a rare large vessel vasculitis, affecting the aorta and its major branches, typically in young women. In this case report, we present three cases of young women of Caucasian descent who experienced relapses while under treatment with the monoclonal humanized antibody to the interleukin 6 receptor, tocilizumab. Active vasculitic lesions of the supraaortic (common carotid and axillary) arteries were detected and characterized via high resolution contrast enhanced ultrasound. Based on these cases, we discuss the potential role of contrast enhanced ultrasound in the diagnosis an...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - December 22, 2017 Category: Surgery Authors: Czihal M, Lottspeich C, Schröttle A, Treitl KM, Treitl M, Leipe J, Schulze-Koops H, Hoffmann U, Dechant C Tags: Vasa Source Type: research

Posterior nutcracker syndrome - a systematic review.
Abstract Posterior nutcracker syndrome (PNCS) is the entrapment of the left renal vein between the aorta and the vertebral column. Although uncommon, it is still an important diagnosis due to the high morbidity associated with the risk of secondary anaemia from haematuria, from long-term left renal vein hypertension, vascular thrombosis, and even blood clots in the urinary system. A literature search of PubMed and EMBASE databases was performed and 27 publications containing 27 cases were included for the final analysis. The following frequency of clinical signs and symptoms was noted: twenty-five patients had hae...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - November 22, 2017 Category: Surgery Authors: Park JH, Lee GH, Lee SM, Eisenhut M, Kronbichler A, Lee KH, Shin JI Tags: Vasa Source Type: research

Antithrombotic treatment in peripheral artery disease.
Abstract This review treats antithrombotic use for peripheral arterial disease (PAD). In asymptomatic patients, there are no scientific data to support single antiplatelet therapy (SAPT) for primary prophylaxis. In symptomatic PAD, SAPT with aspirin or clopidogrel is indicated. The efficacy of aspirin is controversial. Clopidogrel may be preferred over aspirin. Ticagrelor is not superior to clopidogrel in reducing major adverse cardiovascular events and major adverse limb events, but lowers the risk of ischaemic stroke. In symptomatic PAD, dual antiplatelet therapy (DAPT) with clopidogrel and aspirin does not prov...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - November 21, 2017 Category: Surgery Authors: Olinic DM, Tataru DA, Homorodean C, Spinu M, Olinic M Tags: Vasa Source Type: research

Use of vascular closure devices for endovascular interventions requiring a direct puncture of PETE grafts.
Abstract BACKGROUND: Effectiveness of vascular closure devices during endovascular procedures requiring a direct puncture of a vascular prosthesis placed in the inguinal region is unknown. PATIENTS AND METHODS: The retrospective analysis included 134 patients with a history of polyethylene terephthalate (PETE) graft implantation in the inguinal region. In 20 (15 %) patients, haemostasis was achieved with manual compression, in 21 (16 %) with the StarClose™, and in 93 (69 %) with the AngioSeal™ device. RESULTS: The incidence of vascular complications in the manual compression group was higher ...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - November 21, 2017 Category: Surgery Authors: Milnerowicz AI, Milnerowicz AA, Protasiewicz M, Kuliczkowski W Tags: Vasa Source Type: research

Exploring physical activity behaviour - needs for and interest in a technology-delivered, home-based exercise programme among patients with intermittent claudication.
Abstract BACKGROUND: Supervised walking is a first line therapy in peripheral arterial disease (PAD) with complaints of intermittent claudication. However, uptake of supervised programmes is low. Home-based exercise seems an appealing alternative; especially since technological advances, such as tele-coaching and tele-monitoring, may facilitate the process and support patients when adopting a physically active lifestyle. To guide the development of such an intervention, it is important to identify barriers of physical activity and the needs and interests for technology-enabled exercise in this patient group. ...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - November 16, 2017 Category: Surgery Authors: Cornelis N, Buys R, Fourneau I, Dewit T, Cornelissen V Tags: Vasa Source Type: research

Treatment of femoropopliteal lesions with the AngioSculpt scoring balloon - results from the Heidelberg PANTHER registry.
CONCLUSIONS: Preparation with the AngioSculpt™ scoring balloon offers a safe and valuable treatment option for calcified femoropopliteal lesions. PMID: 29116910 [PubMed - as supplied by publisher] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - November 8, 2017 Category: Surgery Authors: Lugenbiel I, Grebner M, Zhou Q, Strothmeyer A, Vogel B, Cebola R, Müller O, Brado B, Mittnacht M, Kohler B, Katus H, Blessing E Tags: Vasa Source Type: research

Endovascular treatment of penetrating arterial trauma with stent grafts.
CONCLUSIONS: The endovascular treatment of penetrating arterial injuries with covered stents is feasible. However, the criteria used to choose the best method must be individualized. PMID: 29082822 [PubMed - as supplied by publisher] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - October 30, 2017 Category: Surgery Authors: Biagioni RB, Burihan MC, Nasser F, Biagioni LC, Ingrund JC Tags: Vasa Source Type: research

Surgical and endovascular venous arterialization for treatment of critical limb ischaemia.
bane V, Kum S Abstract Patients with critical limb ischaemia have a poor life expectancy. Aggressive revascularization is accepted in order to preserve their independence in the final phase of their lives. Bypass surgery and more recently endovascular interventions with angioplasty and stenting have become the treatment of choice to prevent amputation and to resolve pain. However, as many as 20 % of patients with critical limb ischaemia are unsuitable candidates for a vascular intervention because of extensive occlusions of outflow in the crural and pedal vessels. Such "no-option critical limb ischaemia"...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - October 25, 2017 Category: Surgery Authors: Lichtenberg M, Schreve MA, Ferraresi R, van den Heuvel DAF, Ünlü Ç, Cabane V, Kum S Tags: Vasa Source Type: research

Gender differences in abdominal aortic aneurysms in Germany using health insurance claims data.
rendt CA Abstract BACKGROUND: Endovascular aortic repair (EVAR) has emerged as standard of care for abdominal aortic aneurysm (AAA). Real-world evidence is limited to compare this technology to open repair (OAR). Major gaps exist related to short-term and long-term outcomes, particularly in respect of gender differences. MATERIALS AND METHODS: Health insurance claims data from Germany's third largest insurance provider, DAK-Gesundheit, was used to investigate invasive in-hospital treatment of intact (iAAA) and ruptured AAA (rAAA). Patients operated between October 2008 and April 2015 were included in the stud...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - October 24, 2017 Category: Surgery Authors: Stoberock K, Rieß HC, Debus ES, Schwaneberg T, Kölbel T, Behrendt CA Tags: Vasa Source Type: research

Carotid stenosis - basing treatment on individual patients' needs. Optimal medical therapy alone or accompanied by stenting or endarterectomy.
Abstract Though carotid artery stenosis is a known origin of stroke, risk assessment and treatment modality are not yet satisfactorily established. Guideline updates according to latest evidence are expected shortly. Current clinical weakness concerns in particular the identification of "at-risk" patients. Beside the symptomatic status and the degree of stenosis, further signs of unstable plaque on carotid and cerebral imaging should be considered. Moreover, medical and endovascular therapy are continuously improving. Randomized trials and meta-analyses have shown similar long-term results for protected ...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - October 24, 2017 Category: Surgery Authors: Langhoff R Tags: Vasa Source Type: research

Mortality in endovascular and open abdominal aneurysm repair - trends in Germany.
CONCLUSIONS: The general increase in EVAR procedures in males and females hospitalized for rAAA and iAAA went along with a decrease in in-hospital mortality in males treated with EVAR for iAAA only and an increasing mortality in males treated with OAR for iAAA. PMID: 29034780 [PubMed - as supplied by publisher] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - October 16, 2017 Category: Surgery Authors: von Beckerath O, Schrader S, Katoh M, Luther B, Santosa F, Kröger K Tags: Vasa Source Type: research

Sensitivities of in vivo markers of arterial organ damage in patients with peripheral atherosclerosis.
Abstract BACKGROUND: Biomarkers of vascular diseases such as ankle-brachial index (ABI), peripheral pulse pressure (pPP), central pulse pressure (cPP), and pulse wave velocity (PWV) allow assessment of arterial organ damage (AOD). However, the utility of markers other than ABI in patients with peripheral arterial disease (PAD), which are also associated with a significant increase of cardiovascular events, remains unclear. PATIENTS AND METHODS: Asymptomatic (n = 21) and symptomatic patients (n = 46) with a positive sonography for PAD or history of lower limb revascularization were included. ABI, pPP, cPP, and...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - October 5, 2017 Category: Surgery Authors: Frick M, Baumann F, Sick B, B Wilkinson I, Amann-Vesti B, Husmann M Tags: Vasa Source Type: research

Early clinical outcomes of a novel rheolytic directional thrombectomy technique for patients with iliofemoral deep vein thrombosis.
CONCLUSIONS: In patients with iliofemoral DVT of native or stented vessels, RT followed by stent placement appears to be effective and safe. The novel technique enables single-session DVT treatment in the majority of patients without the need for prolonged CDT. PMID: 28980513 [PubMed - as supplied by publisher] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - October 5, 2017 Category: Surgery Authors: Dopheide JF, Sebastian T, Engelberger RP, Haine A, Kucher N Tags: Vasa Source Type: research

Auricular vagal nerve stimulation in peripheral arterial disease patients.
Abstract BACKGROUND: Auricular nerve stimulation has been proven effective in different diseases. We investigated if a conservative therapeutic alternative for claudication in peripheral arterial occlusive disease (PAD) via electroacupuncture of the outer ear can be established. PATIENTS AND METHODS: In this prospective, double-blinded trial an ear acupuncture using an electroacupuncture device was carried out in 40 PAD patients in Fontaine stage IIb. Twenty patients were randomized to the verum group using a fully functional electroacupuncture device, the other 20 patients received a sham device (control gro...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - September 18, 2017 Category: Surgery Authors: Hackl G, Prenner A, Jud P, Hafner F, Rief P, Seinost G, Pilger E, Brodmann M Tags: Vasa Source Type: research

ESVM guidelines - the diagnosis and management of Raynaud's phenomenon.
rick AL, Sprynger M, Klein-Weigel P, Hafner F, Staub D, Zeman Z Abstract Regarding the clinical diagnosis of Raynaud's phenomenon and its associated conditions, investigations and treatment are substantial, and yet no international consensus has been published regarding the medical management of patients presenting with this condition. Most knowledge on this topic derives from epidemiological surveys and observational studies; few randomized studies are available, almost all relating to drug treatment, and thus these guidelines were developed as an expert consensus document to aid in the diagnosis and management o...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - September 12, 2017 Category: Surgery Authors: Belch J, Carlizza A, Carpentier PH, Constans J, Khan F, Wautrecht JC, Visona A, Heiss C, Brodeman M, Pécsvárady Z, Roztocil K, Colgan MP, Vasic D, Gottsäter A, Amann-Vesti B, Chraim A, Poredoš P, Olinic DM, Madaric J, Nikol S, Herrick AL, Sprynger M, Tags: Vasa Source Type: research

First clinical experience with the Multi-LOC multiple stent delivery system for focal stenting in long femoro-popliteal lesions.
Conclusions: The first clinical experience at six months suggests that the MSDS strategy was safe and effective to treat femoro-popliteal lesions of considerable length (14.5 ± 9.0 cm). Almost half of the lesion length could be saved from stenting while patency was high and TLR rates were acceptably low. PMID: 28854856 [PubMed - as supplied by publisher] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - August 31, 2017 Category: Surgery Authors: Amendt K, Beschorner U, Waliszewski M, Sigl M, Langhoff R, Thalwitzer J, Redlich U, Vogel B, Härtel D, Zeller T Tags: Vasa Source Type: research

History of vascular reactivity models and their involvement in hypertension pathogenesis.
Kassisse DM Abstract Hypertension is a silent and multifactorial disease. Over two centuries ago, the first device to record blood pressure was developed, making it possible to determine normotension and to establish criteria for hypertension. Since then, several studies have contributed to advance knowledge in this area, promoting significant advances in pharmacological treatments and, as a result, increasing survival of hypertensive people. The main models developed for the study of hypertension and the main findings in the vascular area are included in this review. We considered aspects related to vascular reac...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - August 31, 2017 Category: Surgery Authors: Conceição-Vertamatti AG, Borghi F, Canova F, Grassi-Kassisse DM Tags: Vasa Source Type: research

Risk of venous thromboembolism following surgical treatment of superficial venous incompetence.
CONCLUSIONS: Patients undergoing varicose vein procedures have a small but appreciable increased risk of VTE compared to the general population, with the effect persisting at one year. Foam sclerotherapy had a lower incidence of VTE compared to other procedures at 30 days, but this effect did not persist at 90 days or at one year. There was no other significant difference in the incidence of VTE between open, endovenous, and foam sclerotherapy treatments. PMID: 28841090 [PubMed - as supplied by publisher] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - August 25, 2017 Category: Surgery Authors: Barker T, Evison F, Benson R, Tiwari A Tags: Vasa Source Type: research

Percutaneous sclerotherapy for spongiform venous malformations - analysis of patient-evaluated outcome and satisfaction.
CONCLUSIONS: Sclerotherapy for treatment of venous malformations results in significant reduction of symptoms. Multiple treatments are often needed, but patients are willing to undergo them. PMID: 28841126 [PubMed - as supplied by publisher] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - August 25, 2017 Category: Surgery Authors: Clemens RK, Baumann F, Husmann M, Meier TO, Thalhammer C, MacCallum G, Ruth Amann-Vesti B, Alomari AI Tags: Vasa Source Type: research

Multiple stent delivery system Multi-LOC, a new technology for spot-stenting of the femoropopliteal artery - proof of concept study in a preclinical large animal model.
CONCLUSIONS: The multiple stent delivery system was studied in a porcine model, which demonstrated its feasibility. Preclinical experience revealed favourable results concerning stent fracture, restenosis, and patency of spot-stented femoropopliteal arteries. PMID: 28825354 [PubMed - as supplied by publisher] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - August 21, 2017 Category: Surgery Authors: Sigl M, Dudeck O, Jung J, Koelble H, Amendt K Tags: Vasa Source Type: research

Laser-assisted transprosthesial coil embolization combined with thrombin injection for treatment of an endoleak type II after endovascular aneurysm repair.
Abstract The treatment of endoleaks type II had to be adapted to the anatomy of each individual patient. The laser-assisted perforation of the prosthesis can be an easier method to reach the aneurysm sac directly than using transarterial or translumbar approaches. PMID: 28787245 [PubMed - as supplied by publisher] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - August 8, 2017 Category: Surgery Authors: Boehme T, Rastan A, Noory E, Fluegel PC, Zeller T Tags: Vasa Source Type: research

A meta-analysis of monthly variation in occurrence of abdominal aortic aneurysm rupture.
CONCLUSIONS: A significant annual pattern in the occurrence of RAAA with a peak in December to January and a nadir in June to July was identified with significantly more incidence in December than in June and in January than in July. PMID: 28782461 [PubMed - as supplied by publisher] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - August 7, 2017 Category: Surgery Authors: Takagi H, Ando T, Umemoto T Tags: Vasa Source Type: research

Perigraft hygroma - a rare cause of post-EVAR aneurysm growth.
Abstract Development of perigraft hygromas following repair of abdominal aortic aneurysms is extremely rare. A case is presented of a patient who was found to have a large hygroma despite two re-interventions on a previous EVAR. PMID: 28756730 [PubMed - as supplied by publisher] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - July 31, 2017 Category: Surgery Authors: Strouther N, Oshin O, Fisher R, McWilliams R, Torella F Tags: Vasa Source Type: research

Conservative treatment of patients with thromboangiitis obliterans or cannabis-associated arteritis presenting with critical lower limb ischaemia.
Abstract BACKGROUND: Proper management of patients with thromboangiitis obliterans (TAO) or cannabis-associated arteritis (CAA), presenting with critical lower limb ischaemia (CLI) remains controversial, and data are limited. PATIENTS AND METHODS: Patients with TAO or CAA presenting with CLI between 2011 and 2016 were retrospectively evaluated. Patients requiring primary intervention were excluded. Conservative treatment included: (a) weight-adjusted bemiparin plus six hours/day intravenous iloprost for 28 days, (b) aspirin (100 mg/day) plus cilostazol (100 mg twice/day) after discharge, and (c) strict recomm...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - July 28, 2017 Category: Surgery Authors: Galyfos G, Kerasidis S, Kastrisios G, Giannakakis S, Sachmpazidis I, Anastasiadou C, Geropapas G, Papapetrou A, Papacharalampous G, Maltezos C Tags: Vasa Source Type: research

The difference between men and women.
PMID: 28679354 [PubMed - in process] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - July 1, 2017 Category: Surgery Authors: Espinola-Klein C Tags: Vasa Source Type: research

Oxidative injury associated with stenting of asymptomatic carotid artery stenosis.
PMID: 28679355 [PubMed - in process] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - July 1, 2017 Category: Surgery Authors: G Moulakakis K Tags: Vasa Source Type: research

Thromboprophylaxis after knee arthroscopy and lower leg casting.
Authors: PMID: 28679356 [PubMed - in process] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - July 1, 2017 Category: Surgery Tags: Vasa Source Type: research

Is contrast enhanced ultrasonography a useful tool for the evaluation of muscular microcirculation in patients with critical limb ischaemia?
PMID: 28665187 [PubMed - as supplied by publisher] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - June 30, 2017 Category: Surgery Authors: Seinturier C, Blaise S, Pichot O, Guigard S, Genty C, Magne JL, Bosson JL, Pernod G, Carpentier PH Tags: Vasa Source Type: research

Primary aorto-enteric fistula as a rare cause of massive gastrointestinal haemorrhage.
l A Abstract The incidence of primary aorto-enteric fistula (PAEF) is low with only few case reports and case series published. Depending on the location of the PAEF, the perforation leads to upper or lower gastrointestinal haemorrhages. We conducted a MEDLINE search according to the PRISMA statement. Articles with publication dates from 2000 to 2016 were included and present an own case report. We considered all case reports and series reporting on PAEF and identified 85 individual patients from 32 case reports and five case series. The majority of PAEF is associated with atherosclerotic or aneurysmatic findings ...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - June 30, 2017 Category: Surgery Authors: Behrendt CA, Wipper S, Debus SE, von Kodolitsch Y, Püschel K, Kammal M, Kammal A Tags: Vasa Source Type: research

Anastomotic leak after surgical repair of type A aortic dissection - prevalence and consequences in midterm follow-up.
CONCLUSIONS: Anastomotic leaks after surgery for Stanford Type A aortic dissection can develop in midterm follow-up, even after initially excellent results. Meticulous follow-up is mandatory to detect possible deterioration and a need for redo surgery. PMID: 28661215 [PubMed - as supplied by publisher] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - June 29, 2017 Category: Surgery Authors: Ghazy T, Mahlmann A, Fajfrova Z, Darwish A, Eraqi M, Hegelmann H, Hoffmann RT, Ouda A, Matschke K, Kappert U, Weiss N Tags: Vasa Source Type: research

Complex interventional iliocaval recanalization due to plasmacytoma and cystic echinococcosis.
l C Abstract Post-thrombotic syndrome is common after iliofemoral vein thrombosis. Conservative therapy, mainly limited to compression and anticoagulation therapy, might not be sufficient in controlling symptoms. Interventional recanalization of the chronically occluded iliac veins is an evolving method, promising rapid relief of symptoms. Here, we present two cases of complex interventions in one patient with preceding pelvic radiotherapy due to a plasmacytoma and in another patient in whom a cava wedge resection had been performed because of cystic echinococcosis in the liver. PMID: 28613113 [PubMed - as su...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - June 14, 2017 Category: Surgery Authors: Stoll F, Kucher N, Vogel B, Katus HA, Müller OJ, Erbel C Tags: Vasa Source Type: research

Initial experience with a new quantitative assessment tool for fluorescent imaging in peripheral artery disease.
ss D, Wipper S Abstract BACKGROUND: Perioperative evaluation in peripheral artery disease (PAD) by common vascular diagnostic tools is limited by open wounds, medial calcinosis or an altered collateral supply of the foot. Indocyanine green fluorescent imaging (ICG-FI) has recently been introduced as an alternative tool, but so far a standardized quantitative assessment of tissue perfusion in vascular surgery has not been performed for this purpose. The aim of this feasibility study was to investigate a new software for quantitative assessment of tissue perfusion in patients with PAD using indocyanine green fluores...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - June 14, 2017 Category: Surgery Authors: Rieß HC, Duprée A, Behrendt CA, Kölbel T, Debus ES, Larena-Avellaneda A, Russ D, Wipper S Tags: Vasa Source Type: research

Paraoxonase-1 and myeloperoxidase correlate with vascular biomarkers in overweight patients with newly diagnosed untreated hyperlipidaemia.
CONCLUSIONS: It can therefore be stated that PON1 activity and MPO level correlate strongly with the vascular biomarkers, highlighting the importance of the HDL-associated pro- and antioxidant enzymes in the development of endothelial dysfunction and atherogenesis. PMID: 28602123 [PubMed - as supplied by publisher] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - June 12, 2017 Category: Surgery Authors: Szentpéteri A, Zsíros N, Varga VE, Lőrincz H, Katkó M, Seres I, Fülöp P, Paragh G, Harangi M Tags: Vasa Source Type: research

Polymorphism rs2073618 of the osteoprotegerin gene as a potential marker of subclinical carotid atherosclerosis in Caucasians with type 2 diabetes mellitus.
CONCLUSIONS: Despite the fact that OPG rs2073618 genotypes failed to predict the serum OPG levels as there was no statistical difference among compared genotypes, our results demonstrate that the rs2073618 polymorphism could be a possible genetic marker for the prediction of increased risk for carotid plaque burden as a measure of advanced subclinical atherosclerosis in T2DM subjects. PMID: 28593808 [PubMed - as supplied by publisher] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - June 8, 2017 Category: Surgery Authors: Pleskovič A, Ramuš SM, Pražnikar ZJ, Šantl Letonja M, Vujkovac AC, Gazdikova K, Caprnda M, Gaspar L, Kruzliak P, Petrovič D Tags: Vasa Source Type: research

Intravenous alprostadil treatment compared to oral pentoxifylline treatment in outpatients with intermittent claudication - results of a randomised clinical trial.
PMID: 28558485 [PubMed - as supplied by publisher] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - May 31, 2017 Category: Surgery Authors: Schellong SM, von Bilderling P, Gruss JD, Lawall H, Grieger F, Ney U, Bramlage P, Diehm C, Bentz J Tags: Vasa Source Type: research

Matrix metalloproteinase-3 gene polymorphism (rs3025058) affects markers atherosclerosis in type 2 diabetes mellitus.
CONCLUSIONS: We found an association between the MMP-3 rs3025058 and subclinical markers of carotid (CIMT) and coronary atherosclerosis at the time of recruitment. Moreover, we demonstrated the effect of the MMP-3 rs3025058 on CIMT progression in the 3.8-year follow-up in patients with T2DM. PMID: 28521653 [PubMed - as supplied by publisher] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - May 19, 2017 Category: Surgery Authors: Pleskovič A, Letonja MŠ, Vujkovac AC, Nikolajević Starčević J, Caprnda M, Curilla E, Mozos I, Kruzliak P, Prosecky R, Petrovič D Tags: Vasa Source Type: research

Statement for Doppler waveforms analysis.
egrave;re A Abstract Peripheral artery disease of the lower limbs (PAD) is a common disease. Evaluation of PAD is primarily based on non-invasive examinations with analysis of the arterial Doppler signal being a key element. However, the description of arterial Doppler waveforms morphologies varies considerably across medical schools and from country to country. In order to overcome this issue, the French College of Teachers for Vascular Medicine (Collège des Enseignants de Médecine Vasculaire; CEMV) has summarised the published data on Doppler waveforms analysis and proposes a new "Saint-Bonnet...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - May 19, 2017 Category: Surgery Authors: Mahé G, Boulon C, Desormais I, Lacroix P, Bressollette L, Guilmot JL, Le Hello C, Sevestre MA, Pernod G, Constans J, Boissier C, Bura-Rivière A Tags: Vasa Source Type: research

Erectile dysfunction - overview from a cardiovascular perspective.
m N Abstract Erectile dysfunction (ED) is an evolving health problem with growing incidence in the ageing male population with potentially predictive value for cardiovascular and other chronic diseases. ED shares the common cardiovascular risk factors. The aetiology of ED is numerous including neurogenic, psychogenic, arteriogenic, and venogenic reasons. The origin of arteriogenic ED is frequently atherosclerosis. Patients not adequately responding to conservative measures including oral medication are often referred to further vascular diagnostics and therapy. At present, the refinements in endovascular therapy a...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - May 10, 2017 Category: Surgery Authors: Baumann F, Hehli D, Makaloski V, Schumacher M, Schönhofen H, Diehm N Tags: Vasa Source Type: research

Rationale and design of the RECording COurses of vasculaR Diseases registry (RECCORD registry).
CONCLUSIONS: The RECCORD registry will provide a comprehensive dataset depicting the current real life practice and outcome of vascular care. The seven predefined quality indicators will be used for benchmarking the participating centres. Moreover, identifying factors promoting a favourable outcome might pave the way for an evidence-based therapeutic strategy and a dedicated therapeutic pathway for patients with PAD including patient-oriented best interventional approaches. In the future, the RECCORD registry may provide a general platform to study the courses of various defined vascular diseases in order to get detailed i...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - May 2, 2017 Category: Surgery Authors: M Malyar N, Stausberg J, Ito WD, Kölble H, Langhoff R, Lawall H, Lichtenberg M, Stegemann J, Treitl M, Weiss N, Hoffmann U Tags: Vasa Source Type: research

Oxidation injury and local mediator interplay in Marfan syndrome.
PMID: 28466775 [PubMed - in process] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - May 1, 2017 Category: Surgery Authors: Tatzber F, Resch U, Wonisch W, Berent R, Sinzinger H Tags: Vasa Source Type: research

Novel imaging techniques to identify unstable arteriosclerotic plaques.
Authors: PMID: 28466776 [PubMed - in process] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - May 1, 2017 Category: Surgery Tags: Vasa Source Type: research

Clinical and duplex ultrasound evaluation of lower extremities varicose veins - a practical guideline.
Abstract Lower extremities varicose veins are among the most frequent diseases in the general population. They can cause complaints with a deterioration of the quality of life and are associated with potentially threatening clinical conditions such as chronic venous ulceration, haemorrhage from ruptured varicose veins, and venous thromboembolism. An accurate diagnostic work-up is crucial to confirm the presence and the extension of the venous problem, in order to obtain an optimal management of the condition. In the past years, great efforts have been made to reach an international consensus on the terminology, th...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - April 27, 2017 Category: Surgery Authors: Spinedi L, Broz P, Peter Engelberger R, Staub D, Uthoff H Tags: Vasa Source Type: research

No relation between biomarkers at age 47-49 and aortic diameter after 14-19 years of follow-up - a population-based study.
CONCLUSIONS: Tested biomarker levels at age 47-49 were not associated with aortic diameter at ultrasound examination after 14-19 years of follow-up. If there are relationships between these biomarkers and aortic dilatation, they are not relevant until closer to AAA diagnosis. PMID: 28447918 [PubMed - as supplied by publisher] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - April 27, 2017 Category: Surgery Authors: Taimour S, Zarrouk M, Holst J, Melander O, Engström G, Smith JG, Gottsäter A Tags: Vasa Source Type: research

Gender differences in endovascular treatment of infrainguinal peripheral artery disease.
t CA Abstract BACKGROUND: Despite ongoing research concerning comorbidities and clinical presentation of peripheral arterial disease (PAD), the issue of gender associated differences in treatment is far from being settled. PATIENTS AND METHODS: This was a prospective, non-randomized multicentre study design. All patients suffering from intermittent claudication (IC) or critical limb ischaemia (CLI) were included. RESULTS: A total of 2,798 procedures for symptomatic PAD in the infrainguinal region were recorded, with 1,696 (61.4 %) males. Distribution of comorbidities for patients with IC were gender-spec...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - April 27, 2017 Category: Surgery Authors: Rieß HC, Debus ES, Heidemann F, Stoberock K, Grundmann RT, Behrendt CA Tags: Vasa Source Type: research

Use of a stent graft in tumor erosion of the common femoral artery with life-threatening bleeding.
We report a case of a 56-year-old male patient with a life-threatening left common femoral artery bleeding due to tumor erosion. The patient had a history of advanced high-grade pleomorphic leiomyosarcoma of the left groin with pulmonary metastasis. Clinical examination revealed a massive tumor bulking at the left groin with necrosis and phleb- and lymphedema. Given the circumstances, open surgery was not possible. Thus, it was decided to treat the patient with an endovascular procedure. The postprocedural course was uneventful, the patient received blood product and was hemodynamically stable. He was discharged at day six...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - March 23, 2017 Category: Surgery Authors: Keo HH, Diehm N, Staub D, Baumann F Tags: Vasa Source Type: research

Changes in carotid artery intima-media thickness during the cardiac cycle - a comparative study in early childhood, mid-childhood, and adulthood.
CONCLUSIONS: Inconsistent timing of CIMT measurement during the cardiac cycle is an avoidable source of imprecision, especially in children, in whom inter-individual differences are smallest. As CIMT is largest at end-diastole, this is the most appropriate time point for consistent and comparable measurements to be made. PMID: 28332441 [PubMed - as supplied by publisher] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - March 23, 2017 Category: Surgery Authors: Rueb K, Mynard J, Liu R, Wake M, Vuillermin P, Ponsonby AL, Zannino D, Burgner DP Tags: Vasa Source Type: research

Ultrasound imaging in the diagnosis of large vessel vasculitis.
Abstract Nowadays noninvasive vascular imaging has an important role in the diagnostic work-up of the large vessel vasculitides (LVV), most importantly giant cell arteritis (GCA) and Takayasu arteritis. Among the imaging modalities available, ultrasound (US) has several important advantages, including low costs, rapid and repetitive availability without exposure to radiation, and high spatial resolution for assessment of large and medium-sized arteries. Therefore, US can be regarded the first line imaging method in suspected LVV. In patients with suspected GCA, US can replace temporal artery biopsy in certain clin...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - March 23, 2017 Category: Surgery Authors: Czihal M, Lottspeich C, Hoffmann U Tags: Vasa Source Type: research

High-resolution magnetic resonance imaging of carotid atherosclerotic plaques - a correlation study with histopathology.
This study aimed to utilize high-resolution magnetic resonance imaging (MRI) to investigate the characteristics of stable and vulnerable carotid arteriosclerotic plaques, with correlations to histopathological findings. PATIENTS AND METHODS: High-resolution MRI was performed in 817 patients, using three-dimensional magnetic resonance angiography. Plaque composition was evaluated by measuring the areas occupied by calcification, a lipid-rich necrotic core, intra-plaque haemorrhage, and fibrous cap rupture. Plaque morphology was analysed by measuring vessel wall area, thickness, and luminal area at the bifurcation of th...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - March 17, 2017 Category: Surgery Authors: Xia Z, Yang H, Yuan X, Wang J, Zhang S, Zhang L, Qu Y, Chen J, Jiao L, Wang LX, Du Y Tags: Vasa Source Type: research

Clinical and diagnostic aspects of lymphedema.
Abstract Lymphedema is a chronic, progressive, and common but often unrecognized condition. The diagnosis of lymphatic disease on clinical grounds alone remains a challenge. Without proper diagnosis, therapy is often delayed, allowing disease progression. There is a need for a practical diagnostic algorithm and its imaging technique to guide clinical decision-making. The aim of this topical review is to provide a practical approach for assessing patients with suspected lymphedema and to give a critical appraisal of currently available imaging modalities that are applied in clinical practice to diagnose and map lym...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - March 10, 2017 Category: Surgery Authors: Keo HH, Gretener SB, Staub D Tags: Vasa Source Type: research

Very distal vein bypass in patients with thromboangiitis obliterans.
CONCLUSIONS: Surgical therapy with distal vein bypass for persistent ischaemic symptoms after definitive cessation of smoking seems feasible in selected cases with TAO and a suitable distal artery. Close follow-ups of the patients with duplex ultrasound are necessary to identify developing vein graft stenoses. Angioplasty seems to be an important part of the long-term therapeutic concept. PMID: 28271745 [PubMed - as supplied by publisher] (Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases)
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - March 8, 2017 Category: Surgery Authors: Neufang A, Vargas-Gomez C, Ewald P, Vitolianos N, Coskun T, Abu-Salim N, Schmiedel R, von Flotow P, Savvidis S Tags: Vasa Source Type: research