Coexistence of IgG4-related disease and ANCA-associated vasculitis: case report and review of the literature
AbstractIgG4-related disease (IgG4-RD) is a fibroinflammatory condition that is characterized by storiform fibrosis, infiltration of IgG4-positive lymphocytes, obliterative phlebitis, and high IgG4 levels. Since IgG4-RD affects a wide variety of organs, a differential diagnosis must include multiple conditions. IgG4-RD is also believed to coexist with certain diseases. In recent years, case reports and case series describing the co-occurrence of IgG4-RD and ANCA-associated vasculitis (AAV) have been published. We intended to evaluate patients with IgG4-RD and AAV overlap in the literature using a case similar to one that w...
Source: Rheumatology International - February 14, 2024 Category: Rheumatology Source Type: research
Prevalence and outcomes of end-stage kidney disease in patients with systemic lupus erythematous: a population-based study
This study aims to examine the prevalence and outcomes of end-stage kidney disease (ESKD) among systemic lupus erythematosus (SLE) patients. SLE patients identified from the national administrative datasets were linked to the Australia and New Zealand Dialysis and Transplant Registry (ANZDATA) to identify the ESKD cases. Period prevalence of ESKD among SLE patients was calculated. The risk of developing ESKD by ethnicity was explored with Cox Proportional Hazards model. The adjusted hazard ratio (HR) of all-cause mortality for M āori, Pacific, Asian compared to European/others was estimated. Of the 2837 SLE patients, 210 ...
Source: Rheumatology International - February 14, 2024 Category: Rheumatology Source Type: research
Increased risk of incident gout in patients with hyperthyroidism: a nationwide retrospective cohort study
AbstractPrevious studies have reported that thyroid dysfunction is associated with increased serum uric acid levels; however, the relationship between hyperthyroidism and incidence of clinical manifestations of gout has not been fully investigated. Therefore, this study aimed to longitudinally investigate the risk of gout in patients with hyperthyroidism. This nationwide retrospective cohort study used data from the Korean National Health Claims Database. We included 76,494 patients with hyperthyroidism and 76,542 age- and sex-matched controls. A Cox proportional hazard regression model was used to adjust for potential con...
Source: Rheumatology International - February 14, 2024 Category: Rheumatology Source Type: research
A lower frequency of inflammatory back pain in male patients with ankylosing spondylitis compared with female patients
AbstractIn routine rheumatology practice, we noticed that a significant number of male ankylosing spondylitis (AS) patients did not experience inflammatory back pain (IBP). Based on this observation, we aimed to investigate the prevalence of IBP in male AS patients and compare it to that in female patients. Patients with AS who fulfilled the modified New York criteria were subjected to a face-to-face interview with a standardized questionnaire that addressed the IBP components based on the Berlin criteria. The study also included 63 patients with chronic mechanical back pain (MBP). Erythrocyte sedimentation rate (ESR) and ...
Source: Rheumatology International - February 14, 2024 Category: Rheumatology Source Type: research
Predictors of treatment failure of non-steroidal anti-inflammatory drugs in patients with axial spondyloarthritis with focus on haptoglobin, haptoglobin polymorphism and zonulin
AbstractAccording to the Assessment of SpondyloArthritis International Society-European Alliance of Associations for Rheumatology (ASAS-EULAR) recommendations for the management of axial spondyloarthritis (axSpA), patients should undergo at least two courses of non-steroidal anti-inflammatory drugs (NSAIDs) therapy. In our study, we enrolled axSpA patients both at onset and in a flare who had already been treated with NSAIDs ineffectively. Subsequently, according to the recommendations, they received modified NSAID treatment as another attempt to the first-line drug therapy and were monitored from there. We aimed to identi...
Source: Rheumatology International - February 14, 2024 Category: Rheumatology Source Type: research
Celebrities influence on rheumatic diseases interest: a Google Trends analysis
AbstractCelebrity-related events have influenced public interest in diseases like cancer, but their impact on rheumatic diseases is poorly investigated. We aimed to investigate whether celebrity-related events may account for atypical interest among Google users in rheumatic diseases. We used Google Trends to generate the relative search volume of 24 adult rheumatic diseases. We visually analyzed global time trends and recorded all dates with unusual spikes of interest. Finally, we used the Google search engine to detect media news related to rheumatic disease that may explain the spikes. The majority of atypical spikes in...
Source: Rheumatology International - February 14, 2024 Category: Rheumatology Source Type: research
Franz Liszt ’s hand osteoarthritis
(Source: Rheumatology International)
Source: Rheumatology International - February 14, 2024 Category: Rheumatology Source Type: research
Advancing AI in rheumatology: critical reflections and proposals for future research using large language models
(Source: Rheumatology International)
Source: Rheumatology International - February 14, 2024 Category: Rheumatology Source Type: research
Progression of subclinical atherosclerosis in ankylosing spondylitis: a 10-year prospective study
AbstractChronic systemic inflammation contributes to increased CVD burden in Ankylosing Spondylitis (AS). Since long-term follow-up data on subclinical atherosclerosis acceleration are lacking, we examined its progression in contemporary AS patients during 10 years. Fifty-three (89% male, aged 50.4 (36.3–55.9) years,) non-diabetic, CVD-free AS patients and 53 age-sex-matched non-diabetic, control individuals were re-evaluated after 9.2–10.2 years by ultrasonography for carotid/femoral atheromatosis, pulse wave velocity (PWV) and intima-media thick ness (IMT), performed by the same operator/protocol. New atheromatic ...
Source: Rheumatology International - February 13, 2024 Category: Rheumatology Source Type: research
Validity and reliability of measurement of peripheral oxygen saturation during the 6-Minute Walk Test in patients with systemic sclerosis
AbstractPeripheral oxygen saturation (SpO2) using the fingers may have important limitations due to Raynaud ’s phenomenon and sclerodactyly in patients with systemic sclerosis (SSc). Sensors located at more central body positions may be more accurate as these as less prone to Raynaud attacks. To determine the validity and reliability of the SpO2 measured at the finger, forehead, and earlobe during the 6-Minute Walk Test (6MWT). Eighty two patients with SSc had an arterial line placed while performing the 6MWT. Peripheral oxygen saturation was simultaneously measured by finger, forehead, and earlobe sensors and compared t...
Source: Rheumatology International - February 10, 2024 Category: Rheumatology Source Type: research
Exploring 5-year changes in general and skin health-related quality of life in psoriatic arthritis patients
AbstractPsoriatic arthritis (PsA) carries a severe disease burden, often leading to deterioration of health-related quality of life (HRQoL). Different comorbidities that are relatively prevalent in PsA are also responsible for compromised HRQoL. To assess real-world data of a 5-year follow-up cohort of PsA patients, focusing on changes in general HRQoL, skin HRQoL, and comorbidities. In this prospective observational study, 114 outpatients diagnosed with PsA were examined at baseline and after 5 years. Data collection included demographics, clinical disease activity measures, and patient-reported outcome measures (PROMs)...
Source: Rheumatology International - February 6, 2024 Category: Rheumatology Source Type: research
Cross-sectional analysis of cardiovascular disease and risk factors in patients with spondyloarthritis: a real-life evidence from biostar nationwide registry
This study aimed to assess the prevalence rates of CV diseases and to analyze the impact of CV risk factors on CV disease in patients with spondyloarthritis. A multi-center cross-sectional study using the BioSTAR (Biological and Targeted Synthetic Disease-Modifying Antirheumatic Drugs Registry) database was performed on patients with spondyloarthritis. Socio-demographic, laboratory, and clinical data were collected. Patients with and without major adve rse cardiovascular events (MACE) were grouped as Group 1 and Group 2. The primary outcome was the overall group’s prevalence rates of CV disease and CV risk factors. Th...
Source: Rheumatology International - February 6, 2024 Category: Rheumatology Source Type: research
Clinical and anamnestic features of patients with systemic vasculitis: a single-center retrospective study
This study aims to analyze the demographic and clinical-anamnestic characteristics of patients with systemic vasculitides in a single centre before and during the COVID-19 pandemic in Kazakhstan. A single-centre retrospective study of medical records of 80 patient s above 18 years was conducted in the Almaty City Rheumatology Center. Medical records of 24 males (30%) and 56 females (70%) with systemic vasculitides, diagnosed from January 2019 to December 2021, were analyzed. Age, gender, damaged organ systems, disability, concomitant diseases, disease experi ence, laboratory data, and other variables were recorded. The re...
Source: Rheumatology International - February 6, 2024 Category: Rheumatology Source Type: research
Systemic sclerosis associated respiratory involvement: Scopus-based analysis of articles in 2013 –2022
ConclusionThis bibliometric analysis offers a comprehensive overview of SSc-ILD research, highlighting its dynamic and interdisciplinary nature. The surge in publications, citation scores, and the identification of key contributors underscore the continued relevance and impact of this field. The nuanced relationships between social attention and scientific recognition, as revealed by Mendeley readership and AAS, contribute to a deeper understanding of the multifaceted nature of scholarly impact. (Source: Rheumatology International)
Source: Rheumatology International - February 6, 2024 Category: Rheumatology Source Type: research
Telerehabilitation: lessons from the COVID-19 pandemic and future perspectives
AbstractThe coronavirus disease 2019 (COVID-19) pandemic has had an enormous effect on healthcare, notably rehabilitation for neurological, rheumatological, musculoskeletal, and cognitive diseases. Telerehabilitation provides rehabilitation services via multiple modalities, such as real-time chats, computerized consultations, and distant evaluations, emphasizing assessment, diagnosis, and intervention. While the use of telerehabilitation had restrictions before COVID-19, regulatory changes have accelerated its adoption, broadening therapy provision beyond tradition al healthcare settings. Telerehabilitation has been ex...
Source: Rheumatology International - February 6, 2024 Category: Rheumatology Source Type: research
