Operculina turpethum (Linn.) Silva Manso as a Medicinal Plant Species: A Review on Bioactive Components and Pharmacological Properties.
Authors: Gupta S, Ved A Abstract Operculina turpethum (Linn.) (OT) Silva Manso belongs to the family Convolvulaceae. This review incorporates literature for the phytochemical and pharmacological profile of OT herb. Exhaustive literature survey was done using all the details on phytochemistry and pharmacology of OT available. This herb was found to be a potent source of bioactive compounds such as α- and β-turpethein, turpethinic acids (A, B, C, D, and E), coumarins, cycloartenol, lanosta-5-ene, 24-methylene-δ-5-lanosterol, α- and β-rhamnose, β-sitosterol, lupeol, scopoletin, betulin, acrylamide, stig...
Source: Pharmacognosy Reviews - October 12, 2017 Category: Drugs & Pharmacology Tags: Pharmacogn Rev Source Type: research

Psidium guajava: A Single Plant for Multiple Health Problems of Rural Indian Population.
In conclusion, popularization of guava, can have multiple applications for rural communities. PMID: 28989253 [PubMed] (Source: Pharmacognosy Reviews)
Source: Pharmacognosy Reviews - October 12, 2017 Category: Drugs & Pharmacology Tags: Pharmacogn Rev Source Type: research

Review of Angiotensin-converting Enzyme Inhibitory Assay: Rapid Method in Drug Discovery of Herbal Plants.
Authors: Ahmad I, Yanuar A, Mulia K, Mun'im A Abstract The renin-angiotensin-aldosterone system is a signaling pathway which responsible in the blood pressure regulation. Angiotensin-converting enzyme (ACE) is one of the key elements responsible for the hypertensive mechanism. It converts angiotensin-I to angiotensin-II. The discovery history of the ACE inhibitory activity assay method has been through a long stage for decades and development continues until today. The ACE inhibitory activity has become an effective screening method in the search for new antihypertensive agents from herbal plants. Some of ...
Source: Pharmacognosy Reviews - May 17, 2017 Category: Drugs & Pharmacology Tags: Pharmacogn Rev Source Type: research

Reflections about Osteoarthritis and Curcuma longa.
Authors: Akuri MC, Barbalho SM, Val RM, Guiguer EL Abstract Osteoarthritis (OA) is a chronic inflammatory degenerative process that affects joints such as the hands, hips, shoulders, feet, spine, and especially knees in millions of people worldwide. Some authors have shown that Curcuma longa components may exhibit benefic effects in the treatment of degenerative diseases as OA. This plant belongs to the family Zingiberaceae and it is popularly known as turmeric or saffron. This review intended to perform a retrospective search to identify studies involving humans and animal models. This review was based on...
Source: Pharmacognosy Reviews - May 17, 2017 Category: Drugs & Pharmacology Tags: Pharmacogn Rev Source Type: research

An Updated Phytopharmacological Review on Medicinal Plant of Arab Region: Apium graveolens Linn.
Authors: Al-Asmari AK, Athar MT, Kadasah SG Abstract Apium graveolens Linn. (Karafs) is used in traditional medicine for the treatment of the various ailments. There is a need to explore and authenticate the pharmacological profile and medicinal importance of the Karafs. In this paper, the literature and the published work on Apium were collected using online resources "Google scholar", "Web of science", "Scopus" and "PubMed". Each of the pharmacological activity was searched individually using the keywords "Apium/Karafs/Apium graveolens + individual pharmacological activity". We documented the most cited ...
Source: Pharmacognosy Reviews - May 17, 2017 Category: Drugs & Pharmacology Tags: Pharmacogn Rev Source Type: research

Antifertility Effect of Bougainvillea spectabilis or Paper Flower.
Authors: Ghogar A, Jiraungkoorskul W Abstract Bougainvillea spectabilis (Family: Nyctaginaceae), commonly referred to as Great Bougainvillea or Paper Flower, is one of the traditional medicinal plants with potential antifertility activity. The aqueous extract and decoction of this plant have been used as fertility control among the tribal people in many countries. Furthermore, it has been shown to possess anticancer, antidiabetic, antihepatotoxic, anti-inflammatory, antihyperlipidemic, antimicrobial, antioxidant, and antiulcer properties. Its phytoconstituents such as alkaloids, essential oils, flavonoids,...
Source: Pharmacognosy Reviews - May 17, 2017 Category: Drugs & Pharmacology Tags: Pharmacogn Rev Source Type: research

Current Understanding of Antiobesity Property of Capsaicin.
Authors: Narang N, Jiraungkoorskul W, Jamrus P Abstract The capsaicin is an ingredient that we normally mix in food in many cultural cuisines even in fresh and dried production. Because of its anticancer, anticholesterolemic, antidiabetic, antihypertensive, anti-inflammatory, antimicrobial, and antioxidant properties, capsaicin is used worldwide. Moreover, capsaicin is also used for the protection of cardiovascular and hepatic diseases. The electronic databases PubMed, Scopus, Web of Science, Google Scholar, and ScienceDirect were searched since 2000 to present for antiobesity term. This review article is ...
Source: Pharmacognosy Reviews - May 17, 2017 Category: Drugs & Pharmacology Tags: Pharmacogn Rev Source Type: research

Fingerroot, Boesenbergia rotunda and its Aphrodisiac Activity.
Authors: Ongwisespaiboon O, Jiraungkoorskul W Abstract Boesenbergia rotunda (Family: Zingiberaceae) as known as fingerroot is a daily food ingredient and traditional medicinal plant in Southeast Asia and Indo-China. It has been shown to possess anti-allergic, antibacterial, anticancer, anti-inflammatory, antioxidant, and antiulcer activities and also shown wound healing. Its common phytochemical components include alkaloids, essential oils, flavonoids, and phenolics. This plant is rich in boesenbergin, krachaizin, panduratin, and pinostrobin, all of which has been reported to contribute to its remedial pro...
Source: Pharmacognosy Reviews - May 17, 2017 Category: Drugs & Pharmacology Tags: Pharmacogn Rev Source Type: research

An Update Review on the Anthelmintic Activity of Bitter Gourd, Momordica charantia.
Authors: Poolperm S, Jiraungkoorskul W Abstract Momordica charantia (Family: Cucurbitales), as known as bitter melon or gourd, is a daily consumption as food and traditional medicinal plant in Southeast Asia and Indo-China. It has been shown to possess anticancer, antidepressant, antidiabetic, anti-inflammatory, antimicrobial, antiobesity, antioxidant, and antiulcer properties. Its common phytochemical components include alkaloids, charantin, flavonoids, glycosides, phenolics, tannins, and terpenoids. This plant is rich in various saponins including momordicin, momordin, momordicoside, karavilagenin, karav...
Source: Pharmacognosy Reviews - May 17, 2017 Category: Drugs & Pharmacology Tags: Pharmacogn Rev Source Type: research

Wound Healing Property Review of Siam Weed, Chromolaena odorata.
Authors: Sirinthipaporn A, Jiraungkoorskul W Abstract Chromolaena odorata (Family: Asteraceae) synonyms as Eupatorium odoratum is a traditional medicinal plant that is widely used for its wound healing property. In particular, the several parts of this herb have been used to treat wounds, burns, and skin infections. Furthermore, it has also been shown to possess anticancer, antidiabetic, anti-hepatotoxic, anti-inflammatory, antimicrobial, and antioxidant properties. Its phytochemical components are alkaloids, flavonoids, flavanone, essential oils, phenolics, saponins, tannins, and terpenoids. The other imp...
Source: Pharmacognosy Reviews - May 17, 2017 Category: Drugs & Pharmacology Tags: Pharmacogn Rev Source Type: research

Pea, Pisum sativum, and Its Anticancer Activity.
Authors: Rungruangmaitree R, Jiraungkoorskul W Abstract Pisum sativum (Family: Fabaceae), as known as green pea or garden pea, has long been important in diet due to its content of fiber, protein, starch, trace elements, and many phytochemical substances. It has been shown to possess antibacterial, antidiabetic, antifungal, anti-inflammatory, antihypercholesterolemia, and antioxidant activities and also shown anticancer property. Its nonnutritive biologically active components include alkaloids, flavonoids, glycosides, isoflavones, phenols, phytosterols, phytic acid, protease inhibitors, saponins, and tann...
Source: Pharmacognosy Reviews - May 17, 2017 Category: Drugs & Pharmacology Tags: Pharmacogn Rev Source Type: research

A Review on the Pharmacological Activities and Phytochemicals of Alpinia officinarum (Galangal) Extracts Derived from Bioassay-Guided Fractionation and Isolation.
Authors: Basri AM, Taha H, Ahmad N Abstract The rhizomes of Alpinia officinarum Hance have been used conventionally for the treatment of various ailments, triggering a wide interest from the scientific research community on this ethnomedicinal plant. This review summarizes the phytochemical and pharmacological properties of the extracts and fractions from A. officinarum, a plant species of the Zingiberaceae family. Different parts of the plant - leaves, roots, rhizomes, and aerial parts - have been extracted in various solvents - methanol, ethanol, ethyl acetate, hexane, dichloromethane, aqueous, chlorofor...
Source: Pharmacognosy Reviews - May 17, 2017 Category: Drugs & Pharmacology Tags: Pharmacogn Rev Source Type: research

Exploration of Phytochemicals Found in Terminalia sp. and their Antiretroviral Activities.
Authors: Dwevedi A, Dwivedi R, Sharma YK Abstract The human immunodeficiency virus (HIV) infects cells of the immune system and destroys their function. Approximately, 2 million people die every year from HIV as reported by the World Health Organization. HIV/AIDS is difficult to treat as the virus continuously develops resistance to drugs being developed. Approach is now turning toward natural products for the development of anti-HIV drugs. Although HIV/AIDS is not a new disease, but research based on plant-derived products is still under clinical trials. Experimentally, it has been proven that plants have...
Source: Pharmacognosy Reviews - January 15, 2017 Category: Drugs & Pharmacology Tags: Pharmacogn Rev Source Type: research

Overviews of Biological Importance of Quercetin: A Bioactive Flavonoid.
Authors: Anand David AV, Arulmoli R, Parasuraman S Abstract Antioxidants are substances that may protect cells from the damage caused by unstable molecules such as free radicals. Flavonoids are phenolic substances widely found in fruits and vegetables. The previous studies showed that the ingestion of flavonoids reduces the risk of cardiovascular diseases, metabolic disorders, and certain types of cancer. These effects are due to the physiological activity of flavonoids in the reduction of oxidative stress, inhibiting low-density lipoproteins oxidation and platelet aggregation, and acting as vasodilators i...
Source: Pharmacognosy Reviews - January 15, 2017 Category: Drugs & Pharmacology Tags: Pharmacogn Rev Source Type: research

Anticancer Alkaloids from Trees: Development into Drugs.
Authors: Isah T Abstract Trees have made an enormous phytochemical contribution in anticancer drugs' development more than any other life form. The contributions include alkaloids that are biosynthesized in various ways and yield. Lead alkaloids isolated from the trees are taxol and camptothecins that currently have annual sales in billion dollars. Other important alkaloids isolated from these life forms include rohitukine, harringtonine, acronycine, thalicarpine, usambarensine, ellipticine, and matrines. Studies on their mechanism of action and target on the DNA and protein of cancerous cells aided the de...
Source: Pharmacognosy Reviews - January 15, 2017 Category: Drugs & Pharmacology Tags: Pharmacogn Rev Source Type: research