Salivary Biomarkers: Noninvasive Ways for Diagnosis of Parkinson's Disease
Neurol Res Int. 2023 Jul 3;2023:3555418. doi: 10.1155/2023/3555418. eCollection 2023.ABSTRACTFinding reliable biomarkers has a crucial role in Parkinson's disease (PD) assessments. Saliva is a bodily fluid, which might be used as a source of biomarkers for PD. Our article has reviewed several publications on salivary proteins in PD patients and their potential as biomarkers. We find out that α-Syn's proportion in oligomeric form is higher in PD patients' saliva, which is potent to use as a biomarker for PD. The salivary concentration of DJ-1 and alpha-amylase is lower in PD patients. Also, substance P level is more modera...
Source: Neurology Research International - July 12, 2023 Category: Neurology Authors: Sanaz Salaramoli Hamid Reza Joshaghani Seyed Isaac Hashemy Source Type: research
