Lithium: An Old Drug for New Therapeutic Strategy for Alzheimer's Disease and Related Dementia
Neurodegener Dis. 2023 Sep 4. doi: 10.1159/000533797. Online ahead of print.ABSTRACTBACKGROUND: Although Alzheimer's disease (AD) is the most common form of dementia, the effective treatment of AD is not available currently. Multiple trials of drugs, which were developed based on the amyloid hypothesis of AD, have not been highly successful to improve cognitive and other symptoms in AD patients, suggesting that it is necessary to explore additional and alternative approaches for the disease-modifying treatment of AD. The diverse lines of evidence have revealed that lithium reduces amyloid and tau pathology, attenuates neur...
Source: Neuro-Degenerative Diseases - September 4, 2023 Category: Neurology Authors: Seong Sool Shim Ken Berglund Shan Ping Yu Source Type: research

Lithium: An Old Drug for New Therapeutic Strategy for Alzheimer's Disease and Related Dementia
Neurodegener Dis. 2023 Sep 4. doi: 10.1159/000533797. Online ahead of print.ABSTRACTBACKGROUND: Although Alzheimer's disease (AD) is the most common form of dementia, the effective treatment of AD is not available currently. Multiple trials of drugs, which were developed based on the amyloid hypothesis of AD, have not been highly successful to improve cognitive and other symptoms in AD patients, suggesting that it is necessary to explore additional and alternative approaches for the disease-modifying treatment of AD. The diverse lines of evidence have revealed that lithium reduces amyloid and tau pathology, attenuates neur...
Source: Neuro-Degenerative Diseases - September 4, 2023 Category: Neurology Authors: Seong Sool Shim Ken Berglund Shan Ping Yu Source Type: research

Lithium: An Old Drug for New Therapeutic Strategy for Alzheimer's Disease and Related Dementia
Neurodegener Dis. 2023 Sep 4. doi: 10.1159/000533797. Online ahead of print.ABSTRACTBACKGROUND: Although Alzheimer's disease (AD) is the most common form of dementia, the effective treatment of AD is not available currently. Multiple trials of drugs, which were developed based on the amyloid hypothesis of AD, have not been highly successful to improve cognitive and other symptoms in AD patients, suggesting that it is necessary to explore additional and alternative approaches for the disease-modifying treatment of AD. The diverse lines of evidence have revealed that lithium reduces amyloid and tau pathology, attenuates neur...
Source: Neuro-Degenerative Diseases - September 4, 2023 Category: Neurology Authors: Seong Sool Shim Ken Berglund Shan Ping Yu Source Type: research

Lithium: An Old Drug for New Therapeutic Strategy for Alzheimer's Disease and Related Dementia
Neurodegener Dis. 2023 Sep 4. doi: 10.1159/000533797. Online ahead of print.ABSTRACTBACKGROUND: Although Alzheimer's disease (AD) is the most common form of dementia, the effective treatment of AD is not available currently. Multiple trials of drugs, which were developed based on the amyloid hypothesis of AD, have not been highly successful to improve cognitive and other symptoms in AD patients, suggesting that it is necessary to explore additional and alternative approaches for the disease-modifying treatment of AD. The diverse lines of evidence have revealed that lithium reduces amyloid and tau pathology, attenuates neur...
Source: Neuro-Degenerative Diseases - September 4, 2023 Category: Neurology Authors: Seong Sool Shim Ken Berglund Shan Ping Yu Source Type: research

Lithium: An Old Drug for New Therapeutic Strategy for Alzheimer's Disease and Related Dementia
Neurodegener Dis. 2023 Sep 4. doi: 10.1159/000533797. Online ahead of print.ABSTRACTBACKGROUND: Although Alzheimer's disease (AD) is the most common form of dementia, the effective treatment of AD is not available currently. Multiple trials of drugs, which were developed based on the amyloid hypothesis of AD, have not been highly successful to improve cognitive and other symptoms in AD patients, suggesting that it is necessary to explore additional and alternative approaches for the disease-modifying treatment of AD. The diverse lines of evidence have revealed that lithium reduces amyloid and tau pathology, attenuates neur...
Source: Neuro-Degenerative Diseases - September 4, 2023 Category: Neurology Authors: Seong Sool Shim Ken Berglund Shan Ping Yu Source Type: research

Lithium: An Old Drug for New Therapeutic Strategy for Alzheimer's Disease and Related Dementia
Neurodegener Dis. 2023 Sep 4. doi: 10.1159/000533797. Online ahead of print.ABSTRACTBACKGROUND: Although Alzheimer's disease (AD) is the most common form of dementia, the effective treatment of AD is not available currently. Multiple trials of drugs, which were developed based on the amyloid hypothesis of AD, have not been highly successful to improve cognitive and other symptoms in AD patients, suggesting that it is necessary to explore additional and alternative approaches for the disease-modifying treatment of AD. The diverse lines of evidence have revealed that lithium reduces amyloid and tau pathology, attenuates neur...
Source: Neuro-Degenerative Diseases - September 4, 2023 Category: Neurology Authors: Seong Sool Shim Ken Berglund Shan Ping Yu Source Type: research

Lithium: An Old Drug for New Therapeutic Strategy for Alzheimer's Disease and Related Dementia
Neurodegener Dis. 2023 Sep 4. doi: 10.1159/000533797. Online ahead of print.ABSTRACTBACKGROUND: Although Alzheimer's disease (AD) is the most common form of dementia, the effective treatment of AD is not available currently. Multiple trials of drugs, which were developed based on the amyloid hypothesis of AD, have not been highly successful to improve cognitive and other symptoms in AD patients, suggesting that it is necessary to explore additional and alternative approaches for the disease-modifying treatment of AD. The diverse lines of evidence have revealed that lithium reduces amyloid and tau pathology, attenuates neur...
Source: Neuro-Degenerative Diseases - September 4, 2023 Category: Neurology Authors: Seong Sool Shim Ken Berglund Shan Ping Yu Source Type: research

Lithium: An Old Drug for New Therapeutic Strategy for Alzheimer's Disease and Related Dementia
Neurodegener Dis. 2023 Sep 4. doi: 10.1159/000533797. Online ahead of print.ABSTRACTBACKGROUND: Although Alzheimer's disease (AD) is the most common form of dementia, the effective treatment of AD is not available currently. Multiple trials of drugs, which were developed based on the amyloid hypothesis of AD, have not been highly successful to improve cognitive and other symptoms in AD patients, suggesting that it is necessary to explore additional and alternative approaches for the disease-modifying treatment of AD. The diverse lines of evidence have revealed that lithium reduces amyloid and tau pathology, attenuates neur...
Source: Neuro-Degenerative Diseases - September 4, 2023 Category: Neurology Authors: Seong Sool Shim Ken Berglund Shan Ping Yu Source Type: research

Lithium: An Old Drug for New Therapeutic Strategy for Alzheimer's Disease and Related Dementia
Neurodegener Dis. 2023 Sep 4. doi: 10.1159/000533797. Online ahead of print.ABSTRACTBACKGROUND: Although Alzheimer's disease (AD) is the most common form of dementia, the effective treatment of AD is not available currently. Multiple trials of drugs, which were developed based on the amyloid hypothesis of AD, have not been highly successful to improve cognitive and other symptoms in AD patients, suggesting that it is necessary to explore additional and alternative approaches for the disease-modifying treatment of AD. The diverse lines of evidence have revealed that lithium reduces amyloid and tau pathology, attenuates neur...
Source: Neuro-Degenerative Diseases - September 4, 2023 Category: Neurology Authors: Seong Sool Shim Ken Berglund Shan Ping Yu Source Type: research

Lithium: An Old Drug for New Therapeutic Strategy for Alzheimer's Disease and Related Dementia
Neurodegener Dis. 2023 Sep 4. doi: 10.1159/000533797. Online ahead of print.ABSTRACTBACKGROUND: Although Alzheimer's disease (AD) is the most common form of dementia, the effective treatment of AD is not available currently. Multiple trials of drugs, which were developed based on the amyloid hypothesis of AD, have not been highly successful to improve cognitive and other symptoms in AD patients, suggesting that it is necessary to explore additional and alternative approaches for the disease-modifying treatment of AD. The diverse lines of evidence have revealed that lithium reduces amyloid and tau pathology, attenuates neur...
Source: Neuro-Degenerative Diseases - September 4, 2023 Category: Neurology Authors: Seong Sool Shim Ken Berglund Shan Ping Yu Source Type: research

Lithium: An Old Drug for New Therapeutic Strategy for Alzheimer's Disease and Related Dementia
Neurodegener Dis. 2023 Sep 4. doi: 10.1159/000533797. Online ahead of print.ABSTRACTBACKGROUND: Although Alzheimer's disease (AD) is the most common form of dementia, the effective treatment of AD is not available currently. Multiple trials of drugs, which were developed based on the amyloid hypothesis of AD, have not been highly successful to improve cognitive and other symptoms in AD patients, suggesting that it is necessary to explore additional and alternative approaches for the disease-modifying treatment of AD. The diverse lines of evidence have revealed that lithium reduces amyloid and tau pathology, attenuates neur...
Source: Neuro-Degenerative Diseases - September 4, 2023 Category: Neurology Authors: Seong Sool Shim Ken Berglund Shan Ping Yu Source Type: research

Lithium: An Old Drug for New Therapeutic Strategy for Alzheimer's Disease and Related Dementia
Neurodegener Dis. 2023 Sep 4. doi: 10.1159/000533797. Online ahead of print.ABSTRACTBACKGROUND: Although Alzheimer's disease (AD) is the most common form of dementia, the effective treatment of AD is not available currently. Multiple trials of drugs, which were developed based on the amyloid hypothesis of AD, have not been highly successful to improve cognitive and other symptoms in AD patients, suggesting that it is necessary to explore additional and alternative approaches for the disease-modifying treatment of AD. The diverse lines of evidence have revealed that lithium reduces amyloid and tau pathology, attenuates neur...
Source: Neuro-Degenerative Diseases - September 4, 2023 Category: Neurology Authors: Seong Sool Shim Ken Berglund Shan Ping Yu Source Type: research

Lithium: An Old Drug for New Therapeutic Strategy for Alzheimer's Disease and Related Dementia
Neurodegener Dis. 2023 Sep 4. doi: 10.1159/000533797. Online ahead of print.ABSTRACTBACKGROUND: Although Alzheimer's disease (AD) is the most common form of dementia, the effective treatment of AD is not available currently. Multiple trials of drugs, which were developed based on the amyloid hypothesis of AD, have not been highly successful to improve cognitive and other symptoms in AD patients, suggesting that it is necessary to explore additional and alternative approaches for the disease-modifying treatment of AD. The diverse lines of evidence have revealed that lithium reduces amyloid and tau pathology, attenuates neur...
Source: Neuro-Degenerative Diseases - September 4, 2023 Category: Neurology Authors: Seong Sool Shim Ken Berglund Shan Ping Yu Source Type: research

A Pivotal Time
Neurodegener Dis. 2023 Aug 3:1-3. doi: 10.1159/000531867. Online ahead of print.NO ABSTRACTPMID:37536295 | DOI:10.1159/000531867 (Source: Neuro-Degenerative Diseases)
Source: Neuro-Degenerative Diseases - August 3, 2023 Category: Neurology Authors: Gilles Allali Source Type: research

A Pivotal Time
Neurodegener Dis. 2023 Aug 3:1-3. doi: 10.1159/000531867. Online ahead of print.NO ABSTRACTPMID:37536295 | DOI:10.1159/000531867 (Source: Neuro-Degenerative Diseases)
Source: Neuro-Degenerative Diseases - August 3, 2023 Category: Neurology Authors: Gilles Allali Source Type: research