COVID-19 vaccines in patients with cancer: immunogenicity, efficacy and safety
Nature Reviews Clinical Oncology, Published online: 11 March 2022; doi:10.1038/s41571-022-00610-8Vaccination against COVID-19 confers robust protection from severe disease. However, the extent to which this applies to patients with cancer remains uncertain given that these patients were excluded from most of the pivotal studies. In this Review, the authors provide an overview of the efficacy and immunogenicity of COVID-19 vaccines in patients with cancer, and discuss alternatives to vaccination for those who might be unable to develop a proficient immune response following vaccination. (Source: Nature Reviews Clinical Oncology)
Source: Nature Reviews Clinical Oncology - March 11, 2022 Category: Cancer & Oncology Authors: Annika Fendler Elisabeth G. E. de Vries Corine H. GeurtsvanKessel John B. Haanen Bernhard W örmann Samra Turajlic Marie von Lilienfeld-Toal Source Type: research

Quality versus quantity in surgical oncology — what is the future?
Nature Reviews Clinical Oncology, Published online: 09 March 2022; doi:10.1038/s41571-022-00617-1Quality versus quantity in surgical oncology — what is the future? (Source: Nature Reviews Clinical Oncology)
Source: Nature Reviews Clinical Oncology - March 9, 2022 Category: Cancer & Oncology Authors: Philip Baum Jacopo Lenzi Samantha Taber Hauke Winter Armin Wiegering Source Type: research

Darolutamide combo is a sensible option for mHSPC
Nature Reviews Clinical Oncology, Published online: 08 March 2022; doi:10.1038/s41571-022-00616-2Darolutamide combo is a sensible option for mHSPC (Source: Nature Reviews Clinical Oncology)
Source: Nature Reviews Clinical Oncology - March 8, 2022 Category: Cancer & Oncology Authors: Annette Fenner Source Type: research

Maintenance capecitabine is beneficial in NPC
Nature Reviews Clinical Oncology, Published online: 07 March 2022; doi:10.1038/s41571-022-00618-0Maintenance capecitabine is beneficial in NPC (Source: Nature Reviews Clinical Oncology)
Source: Nature Reviews Clinical Oncology - March 7, 2022 Category: Cancer & Oncology Authors: David Killock Source Type: research

New treatment strategies for advanced-stage gastrointestinal stromal tumours
Nature Reviews Clinical Oncology, Published online: 25 February 2022; doi:10.1038/s41571-022-00606-4Gastrointestinal stromal tumour (GIST) is the most common form of sarcoma and has become a paradigm of precision medicine owing to the fact that almost all patients harbour one of several known molecule drivers, most of which can be targeted therapeutically. Nevertheless, novel therapeutic strategies are required to overcome the intrinsic resistance of certain subtypes of GIST to existing treatments as well as the acquired resistance that eventually arises in initially sensitive subtypes. This Review describes the biology of...
Source: Nature Reviews Clinical Oncology - February 25, 2022 Category: Cancer & Oncology Authors: Lillian R. Klug Homma M. Khosroyani Jason D. Kent Michael C. Heinrich Source Type: research