Contents
(Source: Medicine)
Source: Medicine - November 29, 2022 Category: Internal Medicine Source Type: research

Editorial Board
(Source: Medicine)
Source: Medicine - November 29, 2022 Category: Internal Medicine Source Type: research

Automated identification and quantification of traumatic brain injury from CT scans: Are we there yet?
Conclusion: We identified several important TBI-related CT findings that can be automatically identified and quantified with AI. A combination of these techniques may provide useful tools to enhance reproducibility of TBI identification and quantification by supporting radiologists and clinicians in their TBI assessments and reducing subjective human factors. (Source: Medicine)
Source: Medicine - November 25, 2022 Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research

Rare presentation in a rare case of pancreatic extraosseous Ewing’s sarcoma: A case report
Rationale: Extraosseous Ewing’s sarcoma is a rare tumor which is aggressive with poor prognosis; it can occur anywhere in the body, but scantily in the pancreas. Pancreatic Ewing’s sarcoma is not reported commonly, with inconsistent clinical manifestations. In this regard, early recognition of this disease is very important for the patient’s sake. Patient concerns: A 16-year-old boy presented with left lower quadrant abdominal pain for 2 months, and left flank pain with dysuria for 1 month. Diagnosis: Abdominal and renal ultrasonography found a mass between the spleen and left kidney as well as left...
Source: Medicine - November 25, 2022 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Use self-gravitation traction to treat lumbar disc herniation: Study protocol for a double-center, single-blind randomized controlled trial
This study aims to evaluate the effectiveness and safety of the self-gravitation traction device in the treatment of LDH and to confirm its positive treatment effect. Methodology: This trial is designed as a pragmatic double-center, single-blind, and 3-arm (1:1:1 ratio) randomized controlled trial. The recruited patients with LDH will be randomly allocated to the intervention (traction weight is 40% or 60% of its body weight) or control (traction weight is 20% of its body weight) group. Traction will be completed within 6 consecutive weeks (3 times a week), with 10 minutes of traction for the first 3 weeks, 20 minut...
Source: Medicine - November 25, 2022 Category: Internal Medicine Tags: Research Article: Study Protocol Clinical Trial Source Type: research

A comparative investigator-initiated pilot study on the efficacy and safety of biodegradable microneedle acupuncture and conventional intradermal acupuncture for dry eye patient: A superiority, assessor-blinded, randomized controlled trial
This study aims to assess the efficacy and safety of a novel medical device, the biodegradable microneedle acupuncture (BMA), using a traditional intradermal acupuncture needle as the control acupuncture for dry eye. Method: This study will be an investigator-initiated, assessor-blinded, comparative, superiority pilot randomized controlled trial. A total of 30 patients with dry eye will be randomly assigned to the experimental or the control group in equal proportion. For the experimental group, the BMA will be applied to both sides of 5 acupoints including BL2, GB14, TE23, EX-HN5, and ST1. For the control group, co...
Source: Medicine - November 25, 2022 Category: Internal Medicine Tags: Research Article: Study Protocol Clinical Trial Source Type: research

The efficacy and safety of platinum-based chemotherapy for ovarian cancer in pregnancy: A protocol for systematic review and meta-analysis
Conclusion: This paper will provide high-quality synthesis to assess the efficacy and safety of platinum-based chemotherapy for ovarian cancer in pregnancy. (Source: Medicine)
Source: Medicine - November 25, 2022 Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research

Diagnostic test accuracy of PCR by saliva specimen for cytomegalovirus infection in newborn: A protocol for systematic review and meta-analysis
Conclusion: We reported that saliva PCR performed well in the diagnosis of cytomegalovirus infection. (Source: Medicine)
Source: Medicine - November 25, 2022 Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research

Comparison of 4 kinds of traditional Chinese medicine injections to assist in improving clinical indicators of patients with idiopathic pulmonary fibrosis: A systematic review and network meta-analysis
Conclusion: The four TCM injections combined with conventional treatment can effectively improve the clinical indicators of patients with IPF, and the improvement effect of Danhong injection was more obvious. (Source: Medicine)
Source: Medicine - November 25, 2022 Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research

An unusual presentation of diabetic ketoacidosis associated with ascariasis and fungal esophagitis: A case report
Rationale: Gastrointestinal symptoms are most commonly observed in patients with diabetic ketoacidosis (DKA), which usually resolves completely with therapy. However, gastrointestinal symptoms may persist after DKA is resolved. Patient concerns: A 22-year-old female was admitted to hospital for epigastric pain and persistent vomiting. The results of laboratory examination showed fungal esophagitis complicated by DKA. Diagnosis: The patient was diagnosed with DKA associated with ascariasis and fungal esophagitis Outcome: The patient was discharged after treatment Lessons: In this case, despit...
Source: Medicine - November 25, 2022 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Posterior cerebral artery embolism resulting in bilateral paramedian thalamic infarction: A case report
We report a case of bilateral paramedian thalamic infarction with impaired consciousness as the main symptom. The digital subtraction angiography suggested that the left superior cerebellar artery and posterior cerebral artery (PCA) were occluded. Patients concern: A previously 67-year-old man was taken to our hospital after 9.5 hours of acute dizziness and loss of consciousness. Diagnosis: The cranial DWI + MRA suggested acute cerebral infarction in bilateral thalamus and bilateral midbrain, and the left posterior cerebral artery was not clearly visualized. The patient was diagnosed with posterior cerebr...
Source: Medicine - November 25, 2022 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Clinical characteristics and prognosis of patients with glioblastoma: A review of survival analysis of 1674 patients based on SEER database
Conclusions: Older patients diagnosed with GBM have worse survival, and patients with glioma of higher grades have a shorter lifespan. Age, grade, surgery, radiation therapy, and chemotherapy were independent prognostic factors for patients with GBM. (Source: Medicine)
Source: Medicine - November 25, 2022 Category: Internal Medicine Tags: Research Article: Narrative Review Source Type: research

The efficacy and safety of traditional Chinese medicine treating diabetic cardiomyopathy: A protocol for systematic review and meta-analysis
Conclusion: The results of this study provide evidence-based medical evidence for the clinical use of traditional Chinese medicine in the treatment of diabetic heart disease in the future. (Source: Medicine)
Source: Medicine - November 25, 2022 Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research

Histopathological pulmonary findings of survivors and autopsy COVID-19 cases: A bi-center study
The coronavirus disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), evolved into a global pandemic. As ACE2 on the surface of alveolar cells of the lung epithelium is one of the potential target receptors for SARS-CoV-2, the respiratory symptoms are the most common presentation of COVID-19. The aim of our study was to investigate the morphological findings in lung tissue after being infected by SARS-CoV-2 and compare histopathologic changes in patients with COVID-19 infection history who died to those who survived. We analyzed lung tissue samples from 9 patients who died from CO...
Source: Medicine - November 25, 2022 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

A review and meta-analysis of the survival rate of adult with osteonecrosis of the femoral head treated with transtrochanteric rotational osteotomy
Conclusions: The application of TRO surgery in ONFH can effectively relieve patients’ symptoms and they enjoy n a high survival rate, especially for Asian patients. This makes it a promising surgical technique. (Source: Medicine)
Source: Medicine - November 25, 2022 Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research