Automatic feathering algorithm for VMAT craniospinal irradiation: A comprehensive comparison with other VMAT planning strategies
In this study, a treatment planning system-integrated method, named automatic feathering (AF) algorithm, was compared against other volumetric-modulated arc therapy strategies. (Source: Medical Dosimetry)
Source: Medical Dosimetry - September 19, 2020 Category: Radiology Authors: Michele Maddalo, Giovanna Benecchi, Luisa Altabella, Caterina Ghetti, Nunziata D'Abbiero Source Type: research

Dose simulations of an early 20th century kilovoltage pneumonia radiotherapy technique performed with a modern fluoroscope
To simulate an early 20th century viral pneumonia radiotherapy treatment using modern fluoroscopy and evaluated it according to current dose guidelines. Monte Carlo was used to assess the dose distribution on an anthropomorphic phantom. Critical organs were: skin, breasts, esophagus, ribs, vertebrae, heart, thymus, and spinal cord. A 100 kVp beam with 3 mm Al HVL, 25  × 25 cm2 posterior-anterior (PA) field and 50 cm source-to-surface distance were simulated. Simulations had a resolution of 0.4 × 0.4 × 0.06 cm3 and a 6% uncertainty. (Source: Medical Dosimetry)
Source: Medical Dosimetry - September 17, 2020 Category: Radiology Authors: Dante Roa, Harry Moyses, Stephanie Leon, Barbara Hamrick, Gustavo R. Sarria, Benjamin Li, Toshiki Tajima, Ales Necas, Carmen Guzman, Oliver Paucar, Alberto Gonzales, Roger Challco, Modesto Montoya, Zintia Arqque, Andres Gonzales, Jimmy Hernandez, Johnny D Source Type: research

Radiotherapy for the prophylaxis of heterotopic ossification after total hip arthroplasty: A systematic review and meta-analysis of randomized controlled trails
Heterotopic ossification (HO) refers to the formation of lamellar bone in soft tissues and is a significant complication after total hip arthroplasty (THA). Radiotherapy has been proven as an effective prophylaxis especially for those patients with high risk of HO after THA. However the dose, timing, and frequency of radiation have yet to be determined. To compare HO progressions with different radiotherapy strategies and explore an optimal radiation option. We systematically searched PubMed, Embase, and Cochrane Library for randomized controlled trails (through December 1, 2019; no language restrictions) collecting patien...
Source: Medical Dosimetry - September 10, 2020 Category: Radiology Authors: Zheng-Hao Hu, Wang Chen, Jian-Ning Sun, Ye Zhang, Yu Zhang, Xiang-Yang Chen, Shuo Feng Source Type: research

Patient-specific radiotherapy quality assurance for estimating actual treatment dose
This study aimed to evaluate the optimal method for planning computed tomography (CT) for prostate cancer radiotherapy to avoid a dose difference of ≥3% between the actual and planned treatments using multiple acquisition planning CT (MPCT). We calculated the 3-dimensional (3D) displacement error between the pelvic bone and matching fiducial marker on MPCT and cone-beam CT scans of 25 patients who underwent prostate volumetric-modulated arc th erapy for prostate cancer. The correlation of the 3D displacement error and the dose difference between planned and actual treatments was calculated using least squares second-orde...
Source: Medical Dosimetry - September 10, 2020 Category: Radiology Authors: Yoshinori Tanabe, Takayuki Ishida, Hidetoshi Eto, Tatsuhiro Sera, Yuki Emoto, Mototsugu Shimokawa Source Type: research

Dosimetric assessment of bolus for postmastectomy radiotherapy
There remains wide variation in the use of chest wall boluses for postmastectomy radiotherapy, which may result from the need for 2 treatment plans with the commonly used half-time tissue-equivalent 5-mm-thick bolus to achieve a full surface dose. To establish a bolus method requiring one treatment plan, we assessed the surface dose of a thinner daily bolus for all treatment fractions and compared it against the half-time 5-mm-thick bolus. In this basic study, we specifically investigated dosage achieved when using the following: (1) the existing bolus protocol, a half-time 5-mm-thick tissue-equivalent Clearfit bolus (Fuji...
Source: Medical Dosimetry - September 1, 2020 Category: Radiology Authors: Terufumi Kawamoto, Naoto Shikama, Chie Kurokawa, Naoya Hara, Masaki Oshima, Keisuke Sasai Source Type: research

Approach to account for the impact of dental artifacts on VMAT dose distributions when using automated treatment planning
(Source: Medical Dosimetry)
Source: Medical Dosimetry - August 31, 2020 Category: Radiology Source Type: research

Left anterior descending artery avoidance in patients receiving breast irradiation
Dose to the left anterior descending artery (LAD) may be significant in patients receiving left-sided irradiation for breast cancer. We investigated if prospective contouring and avoidance of the LAD during treatment planning were associated with lower LAD dose. (Source: Medical Dosimetry)
Source: Medical Dosimetry - August 29, 2020 Category: Radiology Authors: Aleksander Vayntraub, Thomas J. Quinn, Andrew B. Thompson, Peter Y. Chen, Gregory S. Gustafson, Maha S. Jawad, Joshua T. Dilworth Source Type: research

Assessment of robustness of institutional applied clinical target volume (CTV) to planning target volume (PTV) margin in cervical cancer using biological models
The aim of this study is to investigate the robustness of our institutionally applied clinical target volume (CTV)-to-planning target volume (PTV) margins in cervical cancer patients in terms of an equivalent uniform dose (EUD) based on tumor control probability (TCP). We simulated target motion using 25 IMRT cervical cancer plans to demonstrate the effect of geometrical uncertainties on the EUD and TCP. The different components of the total geometrical uncertainties budget were estimated. The biological effects were compared by calculating the EUDs from the trial DVHs. (Source: Medical Dosimetry)
Source: Medical Dosimetry - August 28, 2020 Category: Radiology Authors: Milovan Savanovi ć, Bojan Štrbac Source Type: research

Ablative Re-irradiation of Inoperable Pancreatic Cancer: A Case Study of Gastrointestinal Sparing through MR-guided Online Adaptive Radiotherapy
(Source: Medical Dosimetry)
Source: Medical Dosimetry - August 24, 2020 Category: Radiology Source Type: research

Radiosurgery treatment planning using conformal arc informed volumetric modulated arc therapy
In this study we introduce, describe, and evaluate a treatment planning technique called Conformal Arc Informed VMAT (CAVMAT), which aims to reduce the dose to healthy tissue while generating highly conformal treatment plans. (Source: Medical Dosimetry)
Source: Medical Dosimetry - August 13, 2020 Category: Radiology Authors: William M. Giles, Edward T. Cullom, Obed A.-O. Laryea, Ahmad Nobah, Victor G.L. Alves, Fang-Fang Yin, John P. Kirkpatrick, Justus D. Adamson Source Type: research

A service line approach: Using whiteboard analytics to improve time efficiency in radiation oncology
The purpose of this study was to develop and implement a custom-designed electronic workflow management tool created by Medlever, Inc, in order to improve efficiency, leverage interoperability and maximize overall labor resources. Administrators and clinicians from five Banner MD Anderson Cancer Center, Department of Radiation Oncology clinics utilized Medlever, Inc. to track and analyze clinical workflow. Real-time data were collected for the duration of 3 months. Time and process data were compared month-to-month from each of the five Banner MD Anderson facilities. (Source: Medical Dosimetry)
Source: Medical Dosimetry - August 13, 2020 Category: Radiology Authors: Shailja Patel, Steven Sutlief, Keith Dennis, Simul Parikh, Lehendrick Turner Tags: 2020 Student Writing Competition - 1st Place Source Type: research

4D in vivo dose verification for real ‐time tumor tracking treatments using EPID dosimetry
The use of sophisticated techniques such as gating and tracking treatments requires additional quality assurance to mitigate increased patient risks. To address this need, we have developed and validated an in vivo method of dose delivery verification for real-time aperture tracking techniques, using an electronic portal imaging device (EPID)-based, on-treatment patient dose reconstruction and a dynamic anthropomorphic phantom. Using 4DCT scan of the phantom, ten individual treatment plans were created, 1 for each of the 10 separate phases of the respiratory cycle. (Source: Medical Dosimetry)
Source: Medical Dosimetry - August 7, 2020 Category: Radiology Authors: Sajjad Aftabi, David Sasaki, Timothy VanBeek, Stephen Pistorius, Boyd McCurdy Source Type: research

Hyper-dense foreign bodies found in the bowel during IGRT following brachytherapy
A 28-year-old female with locally advanced adenocarcinoma of the cervix was undergoing treatment with external beam radiation therapy (EBRT), concurrent chemotherapy and high dose rate brachytherapy (BT). On-board imaging obtained prior to one of her external beam treatments revealed four radiopaque foreign bodies in her abdomen. The patient's treatment was delayed for further work-up of this new finding. Upon further investigation, it was discovered that the patient had recently started taking bismuth subsalicylate tablets (brand name: Pepto-Bismol, Procter& Gamble Co., Cincinnati, OH). (Source: Medical Dosimetry)
Source: Medical Dosimetry - August 6, 2020 Category: Radiology Authors: Irena Dragojevi ć, Kelly Kisling, Daniel Scanderbeg, Gina Mansy Source Type: research

Feasibility of hippocampal avoidance whole brain radiation in patients with hippocampal involvement: Data from a prospective study
Among patients with brain metastases, hippocampal avoidance whole brain radiation (HA-WBRT) preserves neurocognitive function relative to conventional WBRT but the feasibility of hippocampal sparing in patients with metastases in/near the hippocampus is unknown. We identified the incidence of hippocampal/perihippocampal metastases and evaluated the feasibility of HA-WBRT in such patients. (Source: Medical Dosimetry)
Source: Medical Dosimetry - August 6, 2020 Category: Radiology Authors: Grace Lee, Luke Besse, Nayan Lamba, Cindy Hancox, Iquan Usta, Fred Hacker, Paul Catalano, Paul D. Brown, Shyam Tanguturi, Itai Pashtan, John Phillips, Daphne Haas-Kogan, Brian Alexander, Daniel Cagney, Ayal Aizer Source Type: research

4D in vivo dose verification for real-time tumor tracking treatments using EPID dosimetry
The use of sophisticated techniques such as gating and tracking treatments requires additional quality assurance to mitigate increased patient risks. To address this need, we have developed and validated an in vivo method of dose delivery verification for real-time aperture tracking techniques, using an electronic portal imaging device (EPID)-based, on-treatment patient dose reconstruction and a dynamic anthropomorphic phantom. Using 4DCT scan of the phantom, ten individual treatment plans were created, 1 for each of the 10 separate phases of the respiratory cycle. (Source: Medical Dosimetry)
Source: Medical Dosimetry - August 6, 2020 Category: Radiology Authors: Sajjad Aftabi, David Sasaki, Timothy VanBeek, Stephen Pistorius, Boyd McCurdy Source Type: research