Feasibility-guided automated planning for stereotactic treatments of prostate cancer
Significant improvements in plan quality using automated planning have been previously demonstrated. The aim of this study was to develop an optimal automated class solution for stereotactic radiotherapy (SBRT) planning of prostate cancer using the new Feasibility module implemented in the pinnacle evolution. Twelve patients were retrospectively enrolled in this planning study. Five plans were designed for each patient. Four plans were automatically generated using the 4 proposed templates for SBRT optimization implemented in the new pinnacle evolution treatment planning systems, differing for different settings of dose-fa...
Source: Medical Dosimetry - March 27, 2023 Category: Radiology Authors: Carmela Romano, Pietro Viola, Maurizio Craus, Gabriella Macchia, Milena Ferro, Paolo Bonome, Antonio Pierro, Milly Buwenge, Alessandra Arcelli, Alessio Giuseppe Morganti, Francesco Deodato, Savino Cilla Tags: Dosimetry Contribution Source Type: research
Treatment of glioblastoma using MRIdian ® A3i BrainTx™: Imaging and treatment workflow demonstration
For patients with newly diagnosed glioblastoma, the current standard-of-care includes maximal safe resection, followed by concurrent chemoradiotherapy and adjuvant temozolomide, with tumor treating fields. Traditionally, diagnostic imaging is performed pre- and post-resection, without additional dedicated longitudinal imaging to evaluate tumor volumes or other treatment-related changes. However, the recent introduction of MR-guided radiotherapy using the ViewRay MRIdian A3i system includes a dedicated BrainTx package to facilitate the treatment of intracranial tumors and provides daily MR images. (Source: Medical Dosimetry)
Source: Medical Dosimetry - March 23, 2023 Category: Radiology Authors: Alonso La Rosa, Kathryn E. Mittauer, Amy E. Rzepczynski, Michael D. Chuong, Tugce Kutuk, Nema Bassiri, Nicole C. McAllister, Matthew D. Hall, James McCulloch, Diane Alvarez, Roberto Herrera, Alonso N. Gutierrez, Ranjini Tolakanahalli, Yazmin Odia, Manmeet Source Type: research
Leading Past COVID-19: An Analysis of Remote Work Now and Beyond
This study aimed to assess the productivity level and job satisfaction of medical dosimetrists in response to changes in working conditions due to the COVID-19 pandemic. With the assistance from the Medical Dosimetrists Certification Board (MDCB), critical data was gathered via an original instrument conducted and distributed by The University of Texas MD Anderson Cancer Center – School of Health Professions to all current practicing certified medical dosimetrists registered with the MDCB. (Source: Medical Dosimetry)
Source: Medical Dosimetry - March 22, 2023 Category: Radiology Authors: Isaac D. Valdez, Catherine E. Ramirez, Armin Khansari, Ilam Momin, Chase Sitzmann, Mahsa Dehghanpour, Kevin R. Clark Source Type: research
Dosimetric comparison of pencil beam scanning proton therapy with or without multi-leaf collimator versus volumetric-modulated arc therapy for treatment of malignant glioma
This study aimed to examine the dosimetric effect of intensity-modulated proton therapy (IMPT) with a multi-leaf collimator (MLC) in treating malignant glioma. We compared the dose distribution of IMPT with or without MLC (IMPTMLC+ or IMPTMLC-, respectively) using pencil beam scanning and volumetric-modulated arc therapy (VMAT) in simultaneous integrated boost (SIB) plans for 16 patients with malignant gliomas. High- and low-risk target volumes were assessed using D2%, V90%, V95%, homogeneity index (HI), and conformity index (CI). (Source: Medical Dosimetry)
Source: Medical Dosimetry - March 11, 2023 Category: Radiology Authors: Junya Miyata, Yuki Tominaga, Kazuto Kondo, Yasuaki Sonoda, Hideki Hanazawa, Mami Sakai, Satoshi Itasaka, Masataka Oita, Masahiro Kuroda Source Type: research
The transition in practice to reduce bolus use in post-mastectomy radiotherapy: A dosimetric study of skin and subcutaneous tissue
To inform clinical practice for women receiving post-mastectomy radiotherapy (PMRT), this study demonstrates the dosimetric impact of removing daily bolus on skin and subcutaneous tissue. Two planning strategies were used: clinical field-based (n = 30) and volume-based planning (n = 10). The clinical field-based plans were created with bolus and recalculated without bolus for comparison. The volume-based plans were created with bolus to ensure a minimum target coverage of the chest wall PTV and recalculated without bolus. (Source: Medical Dosimetry)
Source: Medical Dosimetry - March 10, 2023 Category: Radiology Authors: Alexandra Guebert, Michael Roumeliotis, Che Hsuan David Wu, Karen Long, Natalie Logie, Tannis Graham, Alison Gourley, Peter Craighead, Michael Sia, Sarah Quirk Source Type: research
Dosimetric assessment of the mono and dual-isocentric VMAT technique based on flattening filter-free beams for SBRT with non-contiguous spinal targets
The study aimed to evaluate the planning characteristics of spinal stereotactic body radiotherapy (SBRT) using mono- and dual-isocentric volumetrically modulated arc therapy (VMAT) techniques. The dosimetric indices were compared between different beam arrangement techniques for spinal SBRT planning, including spinal cord avoidance, planning target volume (PTV) dose coverage, conformity, homogeneity, and gradient index. A total of 8 PTVs were contoured on RANDO phantom computed tomography (CT) images, with 4 PTVs per section of the spine (thoracic and lumbar). (Source: Medical Dosimetry)
Source: Medical Dosimetry - February 24, 2023 Category: Radiology Authors: Shekhar Dwivedi, Sandeep Kansal, Jooli Shukla, Avinav Bharati, Vinod Kumar Dangwal Tags: Medical Physics Contribution Source Type: research
Medical dosimetry virtual clinical education: Mentors ’ perspectives
The COVID-19 pandemic affected the United States in early 2020, and many universities began offering their curriculum remotely. The majority of medical dosimetry programs started to offer both didactic and clinical education in a virtual setting. With COVID-19 social distancing and patient protective measures, many clinical medical dosimetrists also began to work in a remote or hybrid setting. Medical dosimetry students interact and learn from their clinical mentors in this remote clinical environment. (Source: Medical Dosimetry)
Source: Medical Dosimetry - February 18, 2023 Category: Radiology Authors: Jamie Baker, Mahsa Dehghanpour Source Type: research
Perceptions of burnout in medical dosimetry within a postpandemic work environment
According to the World Health Organization, burnout is described as having a negative attitude regarding one's work and being exhausted. Previous studies have shown that occupational burnout exists amongst medical dosimetrists, however, the incidence of medical dosimetrist burnout before and after a pandemic warrant continued research. Medical dosimetrists could be experiencing increased burnout in the workplace postpandemic due to staffing shortages and increased remote planning, which may reduce work performance. (Source: Medical Dosimetry)
Source: Medical Dosimetry - February 10, 2023 Category: Radiology Authors: Todd J. Baumgartner, Keegan Sanborn, Milen Reta, Nishele Lenards, Ashley Hunzeker, Sabrina Zeiler Source Type: research
Lung SBRT treatment planning: a study of VMAT arc selection guided by collision check software
To evaluate the effects of arc geometry on lung stereotactic body radiation therapy (SBRT) plan quality, using collision check software to select safe beam angles. Thirty lung SBRT cases were replanned 10Gy x 5 using 4 volumetric modulated arc therapy (VMAT) geometries: coplanar lateral (cpLAT), coplanar oblique (cpOBL), noncoplanar lateral (ncpLAT) and noncoplanar oblique (ncpOBL). Lateral arcs spanned 180 ° on the affected side whereas the 180° oblique arcs crossed midline to spare healthy tissues. (Source: Medical Dosimetry)
Source: Medical Dosimetry - February 6, 2023 Category: Radiology Authors: Tyrone Hamilton, Jiahan Zhang, Jonathan Wolf, Oluwatosin Kayode, Kristin A. Higgins, Jeffrey Bradley, Xiaofeng Yang, Eduard Schreibmann, Justin Roper Source Type: research
Comparison of intensity-modulated radiation therapy (IMRT), 3D conformal proton therapy and intensity-modulated proton therapy (IMPT) for the treatment of metastatic brain cancer
The purpose of this study has been to compare photon intensity modulated radiation therapy (IMRT) against both conformal and intensity modulated proton therapy (IMPT) plans for metastatic brain cancer. Ten IMRT patients with brain cancer were chosen retrospectively, with prescription doses in the range of 20 to 40 Gy, delivered in 3 to 5 fractions using Varian TrueBeam STx machine. Three proton plans with proton double scattering, single collimation static-IMPT, and energy layer by layer collimation dynamic-IMPT were then generated for the same patients using the Mevion S250 system for conformal plans and the S250i system ...
Source: Medical Dosimetry - January 22, 2023 Category: Radiology Authors: Matthew Sullivan, Hosang Jin, Salahuddin Ahmad Source Type: research
Dose reduction of hippocampus using HyperArc planning in postoperative radiotherapy for primary brain tumors
To compare dosimetric parameters for the hippocampus, organs at risk (OARs), and targets of volumetric modulated arc therapy (VMAT), noncoplanar VMAT (NC-VMAT), and HyperArc (HA) plans in patients undergoing postoperative radiotherapy for primary brain tumors. For 20 patients, HA plans were generated to deliver 40.05 to 60 Gy for the planning target volume (PTV). In addition, doses for the hippocampus and OARs were minimized. The VMAT and NC-VMAT plans were retrospectively generated using the same optimization parameters as those in the HA plans. (Source: Medical Dosimetry)
Source: Medical Dosimetry - January 16, 2023 Category: Radiology Authors: Shingo Ohira, Toshiki Ikawa, Naoyuki Kanayama, Shoki Inui, Yoshihiro Ueda, Masayoshi Miyazaki, Teiji Nishio, Masahiko Koizumi, Koji Konishi Source Type: research
Contralateral breast radiation doses in breast cancer patients treated with helical tomotherapy
We aimed to evaluate contralateral breast doses calculated with a Treatment Planning System (TPS) and verified with metal oxide semiconductor field effect transistor (MOSFET) detectors in patients with early-stage breast cancer (BC) who received helical tomotherapy (HT) after breast-conserving surgery. The dosimetric data of 30 patients (15 left-sided and 15 right-sided) with BC treated with 50.4 Gy to the whole breast and 64.4 Gy to the tumor bed in 28 fractions were analyzed. TPS doses were calculated and MOSFET doses were measured in the contralateral breast (CB) at cranial, caudal, and midpoint and 2 cm lateral to the ...
Source: Medical Dosimetry - December 24, 2022 Category: Radiology Authors: Ezgi Oymak, Recep Bozca, Ozan Cem Guler, Cem Onal Source Type: research
A clinical and time savings evaluation of a deep learning automatic contouring algorithm
Automatic contouring algorithms may streamline clinical workflows by reducing normal organ-at-risk (OAR) contouring time. Here we report the first comprehensive quantitative and qualitative evaluation, along with time savings assessment for a prototype deep learning segmentation algorithm from Siemens Healthineers. The accuracy of contours generated by the prototype were evaluated quantitatively using the Sorensen-Dice coefficient (Dice), Jaccard index (JC), and Hausdorff distance (Haus). Normal pelvic and head and neck OAR contours were evaluated retrospectively comparing the automatic and manual clinical contours in 100 ...
Source: Medical Dosimetry - December 20, 2022 Category: Radiology Authors: John S. Ginn, Hiram A. Gay, Jessica Hilliard, Jainil Shah, Nilesh Mistry, Christian M öhler, Geoffrey D. Hugo, Yao Hao Source Type: research
Direct dosimetric comparison of linear accelerator vs. Gamma Knife fractionated stereotactic radiotherapy (fSRT) of large brain tumors
The purpose of this study was to directly compare the plan quality of Gamma Knife (GK) (Elekta, Stockholm, Sweden)- vs linear accelerator (LINAC)-based delivery techniques for fractionated stereotactic radiotherapy (fSRT) of large brain metastases. Eighteen patients with clinical target volumes (CTVs) larger than 9.5 cc were selected to generate comparative plans for the prescription dose of 9 Gy × 3 fractions, utilizing the Eclipse (Varian, Palo Alto, US) vs Leksell GammaPlan (LGP) (Elekta, Stockholm, Sweden) treatment planning systems (TPS). (Source: Medical Dosimetry)
Source: Medical Dosimetry - December 8, 2022 Category: Radiology Authors: Emel Calugaru, Zachary Whiting, Brandon Delacruz, Daniel Ma, Barbara Garcia, Anuj Goenka, Jenghwa Chang Source Type: research
Improvement in plan quality after Implementation of clinical goals in a large network of cancer centers
Clinical Goals (CG) is a tool available in the Varian Eclipse planning system to objectively and visually evaluate the quality of treatment plans based upon user-defined dose-volume parameters. We defined a set of CG for Stereotactic Radiosurgery (SRS) and Intensity-Modulated Radiotherapy (IMRT) based on published data and guidelines and implemented this in a network of cancer centers in India (American Institute of Oncology). A dosimetric study was performed to compare brain SRS and breast IMRT plan quality before and after CG implementation.The CG defined for SRS plans were target V100% ≥ 98%, dose gradient measure (GM...
Source: Medical Dosimetry - November 18, 2022 Category: Radiology Authors: Hefei Liu, Praveen Nuksani, Malolan Rajagopalan, Mangesh Patil, Krishna Komanduri, Brent Murphy, Deepak Khuntia, Sushil Beriwal Source Type: research
