Journal of Thrombosis and Thrombolysis This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Adverse events in low versus normal body weight patients prescribed apixaban for atrial fibrillation
AbstractSafety and efficacy of direct oral anticoagulants (DOAC) in low weight patients with atrial fibrillation (AF) is unclear due to few low body weight patients enrolled in clinical trials. To assess bleeding and thrombotic event rates for patients with AF that are prescribed apixaban and have a low versus normal body weight. We analyzed patients with AF prescribed apixaban from 2017 to 2020 with at least 12 months of follow-up. Patients were divided into low [< 60 kg (kg)] and normal (60–100 kg) weight cohorts. Bleeding and thrombotic event rates were compared. Poisson regression and Cox proportional hazard ...
Source: Journal of Thrombosis and Thrombolysis - January 30, 2023 Category: Hematology Source Type: research

Risk adjusted venous thromboembolism prophylaxis following pancreatic surgery
This study analyzes pancreatectomy cases performed between 2016 and 2021 to determine the impact of using Caprini guideline indicated VTE prophylaxis on VTE and bleeding complications. This is a retrospective study of cases performed in a single academic health care system, in which Caprini score and VTE prevention measures were determined retroactively and prevention practices binarized as appropriate or not appropriate. Univariate and multivariate analyses were performed of 1,299 pancreatectomy case. Most patients were stratified as high risk for postoperative VTE. Receiving appropriate VTE prophylaxis during admission w...
Source: Journal of Thrombosis and Thrombolysis - January 25, 2023 Category: Hematology Source Type: research

Correction to: Timing of anticoagulation for venous thromboembolism after recent traumatic and vascular brain injury
(Source: Journal of Thrombosis and Thrombolysis)
Source: Journal of Thrombosis and Thrombolysis - January 24, 2023 Category: Hematology Source Type: research

Outcomes with use of extra-corporeal membrane oxygenation in high-risk pulmonary embolism: a national database perspective
AbstractHigh-risk pulmonary embolism (PE) patients can be managed with systemic lysis, catheter-based therapies, or surgical embolectomy. Despite the advent of newer therapies, patients with high-risk PE remain with a 50 –60% short-term mortality risk. In such patients, extracorporeal membrane oxygenation (ECMO) is increasingly utilized for hemodynamic support. To evaluate the outcomes of the use of ECMO in patients with high-risk PE. Using the National Inpatient Sample (NIS) database, we identified patients with high-risk PE using ICD 10 codes and compared in-hospital outcomes of patients with and without ECMO support. ...
Source: Journal of Thrombosis and Thrombolysis - January 20, 2023 Category: Hematology Source Type: research

Correction to: A multicentre observational study of the prevalence, management, and outcomes of subsegmental pulmonary embolism
(Source: Journal of Thrombosis and Thrombolysis)
Source: Journal of Thrombosis and Thrombolysis - January 20, 2023 Category: Hematology Source Type: research

Thrombotic outcomes in patients in a large clinical enterprise following COVID-19 vaccination
AbstractVaccination against COVID-19 reduces infection-related mortality. Unfortunately, reports of vaccine-induced immune thrombotic thrombocytopenia (VITT) in individuals administered adenovirus-vector-based vaccines (ChAdOx1 nCoV-19 and Ad26.COV2.S) have spurred side effect concerns. To address vaccine hesitancy related to this, it is essential to determine the incidence of VITT (defined by a 50% decrease in platelet count and positive anti-PF4 immunoassay within 4 –28 days after vaccination) among patients administered two doses of an mRNA-based COVID-19 vaccination. We identified a retrospective cohort of 223,345 p...
Source: Journal of Thrombosis and Thrombolysis - January 18, 2023 Category: Hematology Source Type: research

Risk of venous thromboembolic events after COVID-19 infection: a systematic review and meta-analysis
AbstractData regarding the occurrence of venous thromboembolic events (VTE), including acute pulmonary embolism (PE) and deep vein thrombosis (DVT) in recovered COVID-19 patients are scant. We performed a systematic review and meta-analysis to assess the risk of acute PE and DVT in COVID-19 recovered subject. Following the PRIMSA guidelines, we searched Medline and Scopus to locate all articles published up to September 1st, 2022, reporting the risk of acute PE and/or DVT in patients recovered from COVID-19 infection compared to non-infected patients who developed VTE over the same follow-up period. PE and DVT risk were ev...
Source: Journal of Thrombosis and Thrombolysis - January 18, 2023 Category: Hematology Source Type: research

Risk of thrombosis in essential thrombocythemia according to three prediction models: an external validation study
Conclusion: The conventional model, which is based on age and history of thrombosis, is the best model to predict thrombotic risk in Thai ET patients. Further studies with a larger number of patients with thrombotic events are needed to validate the IPSET-thrombosis and revised IPSET-thrombosis models. (Source: Journal of Thrombosis and Thrombolysis)
Source: Journal of Thrombosis and Thrombolysis - January 18, 2023 Category: Hematology Source Type: research