Higher Circulating Lymphocytes and the Incidence of Pre-eclampsia and Eclampsia
J Pregnancy. 2024 Mar 19;2024:8834312. doi: 10.1155/2024/8834312. eCollection 2024.ABSTRACTExcessive immune activation contributes to the onset of early dysfunction of the maternal-fetal interface, and it is closely linked to the development of pre-eclampsia. However, the effect of specific immune cells on the risk of pre-eclampsia and eclampsia remains controversial. We investigated the causal relationship between immune cells and pre-eclampsia and eclampsia. For exposure, we extracted genetic variants associated with immune cell-related traits, and for outcomes, we used summary genetic data of pre-eclampsia/eclampsia. A ...
Source: Journal of Pregnancy - March 27, 2024 Category: OBGYN Authors: Qiuping Zhao Rongmei Liu Hui Chen Xiaomo Yang Jiajia Dong Minfu Bai MingYang Yu Zeying Feng Dingyuan Zeng Source Type: research

Validation of a Model for Predicting Magnesium Concentration in Women with Preeclampsia: A Retrospective Cohort Study
CONCLUSIONS: Zuspan regimen is very safe, but slow to reach therapeutic concentrations-despite efforts of individual titration. Success rate is lower in heavy women, which is of particular importance considering their predisposition to develop preeclampsia. The validated pharmacokinetic model performs well and may be used to individually tailor treatment from the outset.PMID:38504794 | PMC:PMC10950413 | DOI:10.1155/2024/1178220 (Source: Journal of Pregnancy)
Source: Journal of Pregnancy - March 20, 2024 Category: OBGYN Authors: Erik Holmstr öm Thalme Magnus Fr ödin-Bolling Source Type: research

Childbirth Self-Efficacy and Its Associated Factors among Pregnant Women in Arba Minch Town, Southern Ethiopia, 2023: A Cross-Sectional Study
CONCLUSIONS: The magnitude of low childbirth self-efficacy was high in the study area. Being primigravida, unplanned pregnancy, age ≤ 24 years, severe fear of childbirth, anxiety, poor social support, and poor knowledge were significantly associated with low childbirth self-efficacy. Therefore, giving special attention to these factors during antenatal care would be important.PMID:38390034 | PMC:PMC10883742 | DOI:10.1155/2024/6478172 (Source: Journal of Pregnancy)
Source: Journal of Pregnancy - February 23, 2024 Category: OBGYN Authors: Tesfahun Simon Kassahun Fikadu Bezawit Afework Habtamu Alemu Begetayinoral Kussia Source Type: research