Journal of Pediatric Hematology Oncology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

In Response to: Pediatric Myelodysplastic Syndrome with Germline RRAS Mutation: Expanding the Phenotype of RASopathies
No abstract available (Source: Journal of Pediatric Hematology Oncology)
Source: Journal of Pediatric Hematology Oncology - February 24, 2022 Category: Hematology Tags: Letters to the Editor Source Type: research

COVID-19 Infection in Children With Cancer: Not A Gloomy Picture
No abstract available (Source: Journal of Pediatric Hematology Oncology)
Source: Journal of Pediatric Hematology Oncology - February 24, 2022 Category: Hematology Tags: Letters to the Editor Source Type: research

6-Mercaptopurine to Induce Remission Despite Graft Failure Post Hematopoietic Cell Transplantation for Juvenile Myelomonocytic Leukemia
No abstract available (Source: Journal of Pediatric Hematology Oncology)
Source: Journal of Pediatric Hematology Oncology - February 24, 2022 Category: Hematology Tags: Letters to the Editor Source Type: research

Pyrites: An Orbital Mass
No abstract available (Source: Journal of Pediatric Hematology Oncology)
Source: Journal of Pediatric Hematology Oncology - February 24, 2022 Category: Hematology Tags: Pyrite Source Type: research

Successful Salvage of Very Early Relapse in Pediatric Acute Lymphoblastic Leukemia With Inotuzumab Ozogamicin and HLA-haploidentical Peripheral Blood Stem Cell Transplantation With Posttransplant Cyclophosphamide
Herein, we describe a 14-year-old female patient with B-cell precursor acute lymphoblastic leukemia who relapsed in early consolidation. Minimal residual disease-negative complete remission was obtained after 1 cycle of inotuzumab ozogamicin therapy. She underwent HLA-haploidentical peripheral blood stem cell transplantation after a myeloablative conditioning regimen. Posttransplant cyclophosphamide, tacrolimus, and mycophenolate mofetil were administered for the prophylaxis of graft-versus-host disease. At 23 months, she was in complete remission. Although the administration of inotuzumab ozogamicin followed by haploident...
Source: Journal of Pediatric Hematology Oncology - February 24, 2022 Category: Hematology Tags: Clinical and Laboratory Observations Source Type: research

Paroxysmal Cold Hemoglobinuria: Diagnosis From the Blood Smear
We present a child with paroxysmal cold hemoglobinuria and prominent neutrophil erythrophagocytosis to highlight the importance of this finding in the diagnosis of paroxysmal cold hemoglobinuria. (Source: Journal of Pediatric Hematology Oncology)
Source: Journal of Pediatric Hematology Oncology - February 24, 2022 Category: Hematology Tags: Morphology Corner Source Type: research

Posterior Reversible Encephalopathy Syndrome: Incidence and Clinical Characteristics in Children With Cancer
The etiology and outcomes of posterior reversible encephalopathy syndrome (PRES) in children with cancer are not well understood. We aim to determine the incidence of PRES, describe associated morbidity and mortality, and better understand risk factors in this patient population. A total of 473 children with a hematologic malignancy or postallogeneic hematopoietic cell transplantation between June 2015 and June 2020 were screened for PRES to determine incidence and whether age or underlying diagnosis are associated with development of PRES. We conducted a case-control study to evaluate whether comorbidities or chemotherape...
Source: Journal of Pediatric Hematology Oncology - February 24, 2022 Category: Hematology Tags: Original Articles Source Type: research

Therapeutic Leukapheresis in Pediatric Leukemia: Utilization Trend and Early Outcomes in a US Nationwide Cohort
Leukapheresis (LA) in pediatric leukemia is performed for leukostasis, a life-threatening emergency in the setting of extremely increased blast cell counts. The authors aimed to assess the epidemiology of pediatric leukemia who received LA. The authors reviewed US nationally representative admission records of patients less than 20 years of age in the Kids’ Inpatient Database for the years 2000, 2003, 2006, 2009, 2012, and 2016. Incidence of new leukemia cases who underwent LA were calculated for the years 2009, 2012, and 2016. Cox and logistic regression analyses were performed to ascertain the risk factors for adverse ...
Source: Journal of Pediatric Hematology Oncology - February 24, 2022 Category: Hematology Tags: Original Articles Source Type: research

High Rates of Central Venous Line Replacement or Revision in Children With Cancer at US Children’s Hospitals
Conclusion: Twenty-five percent require at least 1 RRA within 6 months, with associated morbidity and costs. Though strongly associated, most revisions were not related to CLABSI episodes. (Source: Journal of Pediatric Hematology Oncology)
Source: Journal of Pediatric Hematology Oncology - February 24, 2022 Category: Hematology Tags: Original Articles Source Type: research

Documented Viral Illness at the Time of Splenic Sequestration Does Not Affect the Odds of Recurrence in Children With Sickle Cell Disease
This retrospective study investigates the relationship between the presence of a documented viral infection in children with sickle cell disease during their first splenic sequestration crisis and their odds of recurrence. Forty-eight children were admitted to our hospital between 2008 and 2018 with a splenic sequestration crisis. Thirty-six had respiratory viral panels done on admission, 13 of whom were positive. Two additional children were diagnosed with parvovirus B19 infection by serology. The recurrence rate was 52% (17/33) for those deemed negative for viral illness compared with 33% (5/15) among those with a positi...
Source: Journal of Pediatric Hematology Oncology - February 24, 2022 Category: Hematology Tags: Original Articles Source Type: research

Infantile Hemangioma: A Current Review
Infantile hemangiomas (IHs) are common vascular lesions which are benign but can cause significant functional and cosmetic morbidity. Since the fortuitous discovery of propranolol being effective to treat IH over a decade ago, the therapy and prognosis for children with IH have improved dramatically. Oral propranolol (as well as other oral beta-blockers and topical timolol) are safe and effective treatments, and have now supplanted other therapies. Making the correct diagnosis is crucial, because other vascular lesions can mimic IH. In addition, IH can be the first manifestation of an underlying syndrome. For IH requiring ...
Source: Journal of Pediatric Hematology Oncology - February 24, 2022 Category: Hematology Tags: Review Article Source Type: research

Spontaneous Retrobulbar Hemorrhage in a Previously Healthy Infant
We reported a 5-month-old male infant with sudden onset of left eye proptosis with no prior history of getting vitamin K injection after birth. Head computed tomography scan revealed retrobulbar and intracranial hemorrhages. Laboratory results showed anemia, prolonged prothrombin and activated partial thromboplastin time, supporting the diagnosis of vitamin K deficiency bleeding. After the bleeding and clotting profile were stabilized, lateral canthotomy and cantholysis; and drainage following orbital decompression were successfully performed, yielded in a completely resolved proptosis. The right timing for surgery with th...
Source: Journal of Pediatric Hematology Oncology - January 1, 2022 Category: Hematology Tags: Online Articles: Clinical and Laboratory Observations Source Type: research

Sphenopalatine Ganglion Block for Postdural Puncture Headaches in a Thrombocytopenic Adolescent Young Adult: A Case Report
We present a case of an adolescent with acute lymphocytic leukemia, thrombocytopenia, and persistent postdural puncture headaches. The patient was successfully treated with a sphenopalatine ganglion nerve block at the bedside without any side effects and complications. (Source: Journal of Pediatric Hematology Oncology)
Source: Journal of Pediatric Hematology Oncology - January 1, 2022 Category: Hematology Tags: Online Articles: Clinical and Laboratory Observations Source Type: research

Roseola Infantum During the COVID-19 Pandemic
Conclusion: During the peak of the pandemic, children continued to present with fever because of viral infections other than COVID-19. (Source: Journal of Pediatric Hematology Oncology)
Source: Journal of Pediatric Hematology Oncology - January 1, 2022 Category: Hematology Tags: Online Articles: Clinical and Laboratory Observations Source Type: research

Management of an Immunocompromised Pediatric Patient With Multiple Hospitalizations for Symptomatic COVID-19
We present a case of an adolescent female with B-cell acute lymphoblastic leukemia hospitalized multiple times for symptomatic SARS-CoV-2 infection who was safely treated with 2 courses of remdesivir (RDV) and has had no additional readmissions to date. Though additional studies are needed to confirm the safety and efficacy of an additional course of RDV in the setting of relapsed or prolonged severe COVID-19, our observations suggest that a second course of RDV may be considered. (Source: Journal of Pediatric Hematology Oncology)
Source: Journal of Pediatric Hematology Oncology - January 1, 2022 Category: Hematology Tags: Online Articles: Clinical and Laboratory Observations Source Type: research