International Journal of Alzheimers Disease This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Cyclic Glycine-Proline Improves Memory and Reduces Amyloid Plaque Load in APP/PS1 Transgenic Mouse Model of Alzheimer's Disease
Int J Alzheimers Dis. 2023 Mar 1;2023:1753791. doi: 10.1155/2023/1753791. eCollection 2023.ABSTRACTAlzheimer's disease (AD) is a neurodegenerative condition that is pathologically characterized by the presence of amyloid plaques and neurofibrillary tangles. Animal models of AD have been useful in understanding the disease process and in investigating the effects of compounds on pathology and behavior. APP/PS1 mice develop amyloid plaques and show memory impairment. Cyclic glycine-proline (cGP) is a cyclic dipeptide that is likely produced from a tripeptide, glycine-proline-glutamate, which itself is generated after proteol...
Source: International Journal of Alzheimers Disease - March 13, 2023 Category: Geriatrics Authors: Tushar Arora Shiv K Sharma Source Type: research

CSF-Targeted Proteomics Indicate Amyloid-Beta Ratios in Patients with Alzheimer's Dementia Spectrum
CONCLUSION: Our research suggests potential early diagnostic and prognostic utilities for certain peptides extracted from CSF-targeted proteomics research. The ethical approval of ADNI is available at ClinicalTrials.gov with Identifier: NCT00106899.PMID:36793451 | PMC:PMC9925239 | DOI:10.1155/2023/5336273 (Source: International Journal of Alzheimers Disease)
Source: International Journal of Alzheimers Disease - February 16, 2023 Category: Geriatrics Authors: Maryam Behzad Negin Zirak Ghazal Hamidi Madani Linda Baidoo Ali Rezaei Shima Karbasi Mohammad Sadeghi Mahan Shafie Mahsa Mayeli None Alzheimer's Disease Neuroimaging Initiative Source Type: research