Can breeders prevent pathogen adaptation when selecting for increased resistance to infectious diseases?
Recent research shows that genetic selection has high potential to reduce the prevalence of infectious diseases in livestock. However, like all interventions that target infectious diseases, genetic selection ... (Source: Genetics Selection Evolution)
Source: Genetics Selection Evolution - November 8, 2022 Category: Genetics & Stem Cells Authors: Andries D. Hulst, Piter Bijma and Mart C. M. De Jong Tags: Research Article Source Type: research
A method to obtain exact single-step GBLUP for non-genotyped descendants when the genomic relationship matrix of ancestors is not available
Single-step genomic best linear unbiased prediction (GBLUP) involves a joint analysis of individuals with genotype information, and their ancestors, descendants, or contemporaries, without recorded genotypes. ... (Source: Genetics Selection Evolution)
Source: Genetics Selection Evolution - October 31, 2022 Category: Genetics & Stem Cells Authors: Dorian J. Garrick and Rohan L. Fernando Tags: Research Article Source Type: research
Mutation of the MYH3 gene causes recessive cleft palate in Limousine cattle
The palate is a structure separating the oral and nasal cavities and its integrity is essential for feeding and breathing. The total or partial opening of the palate is called a cleft palate and is a common ma... (Source: Genetics Selection Evolution)
Source: Genetics Selection Evolution - October 29, 2022 Category: Genetics & Stem Cells Authors: Anne Vaiman, S ébastien Fritz, Christian Beauvallet, Mekki Boussaha, Cécile Grohs, Nathalie Daniel-Carlier, Anne Relun, Didier Boichard, Jean-Luc Vilotte and Amandine Duchesne Tags: Research Article Source Type: research
Inbreeding and pedigree analysis of the European red dairy cattle
Red dairy cattle breeds have an important role in the European dairy sector because of their functional characteristics and good health. Extensive pedigree information is available for these breeds and provide... (Source: Genetics Selection Evolution)
Source: Genetics Selection Evolution - October 23, 2022 Category: Genetics & Stem Cells Authors: Sofia Nyman, Anna M. Johansson, Valentina Palucci, Anna A. Sch önherz, Bernt Guldbrandtsen, Dirk Hinrichs and Dirk-Jan de Koning Tags: Research Article Source Type: research
Genetic parameters of colostrum and calf serum antibodies in Swedish dairy cattle
A sufficient IgG content in the colostrum is essential for the newborn calf, as it provides passive immunity which substantially affects the probability of survival during rearing. Failure of passive transfer ... (Source: Genetics Selection Evolution)
Source: Genetics Selection Evolution - October 22, 2022 Category: Genetics & Stem Cells Authors: Juan Cordero-Solorzano, Dirk-Jan de Koning, Madeleine Tr åvén, Therese de Haan, Mathilde Jouffroy, Andrea Larsson, Aline Myrthe, Joop A. J. Arts, Henk K. Parmentier, Henk Bovenhuis and Jonas Johansson Wensman Tags: Research Article Source Type: research
Impacts of additive, dominance, and inbreeding depression effects on genomic evaluation by combining two SNP chips in Canadian Yorkshire pigs bred in China
At the beginning of genomic selection, some Chinese companies genotyped pigs with different single nucleotide polymorphism (SNP) arrays. The obtained genomic data are then combined and to do this, several impu... (Source: Genetics Selection Evolution)
Source: Genetics Selection Evolution - October 22, 2022 Category: Genetics & Stem Cells Authors: Quanshun Mei, Zulma G. Vitezica, Jielin Li, Shuhong Zhao, Andres Legarra and Tao Xiang Tags: Research Article Source Type: research
New insights into the genetic resistance to paratuberculosis in Holstein cattle via single-step genomic evaluation
Bovine paratuberculosis, or Johne ’s disease (JD), is a contagious and incurable disease caused by Mycobacterium avium subsp. paratuberculosis (MAP). It has adverse effects on animal welfare and is very difficult ... (Source: Genetics Selection Evolution)
Source: Genetics Selection Evolution - October 15, 2022 Category: Genetics & Stem Cells Authors: Marie-Pierre Sanchez, Thierry Tribout, S ébastien Fritz, Raphaël Guatteo, Christine Fourichon, Laurent Schibler, Arnaud Delafosse and Didier Boichard Tags: Research Article Source Type: research
Theoretical accuracy for indirect predictions based on SNP effects from single-step GBLUP
Although single-step GBLUP (ssGBLUP) is an animal model, SNP effects can be backsolved from genomic estimated breeding values (GEBV). Predicted SNP effects allow to compute indirect prediction (IP) per individ... (Source: Genetics Selection Evolution)
Source: Genetics Selection Evolution - September 27, 2022 Category: Genetics & Stem Cells Authors: Andre Garcia, Ignacio Aguilar, Andres Legarra, Shogo Tsuruta, Ignacy Misztal and Daniela Lourenco Tags: Research Article Source Type: research
Genomic prediction with whole-genome sequence data in intensely selected pig lines
Early simulations indicated that whole-genome sequence data (WGS) could improve the accuracy of genomic predictions within and across breeds. However, empirical results have been ambiguous so far. Large datase... (Source: Genetics Selection Evolution)
Source: Genetics Selection Evolution - September 24, 2022 Category: Genetics & Stem Cells Authors: Roger Ros-Freixedes, Martin Johnsson, Andrew Whalen, Ching-Yi Chen, Bruno D. Valente, William O. Herring, Gregor Gorjanc and John M. Hickey Tags: Research Article Source Type: research
Causal inference for the covariance between breeding values under identity disequilibrium
The covariance matrix of breeding values is at the heart of prediction methods. Prediction of breeding values can be formulated using either an “observed” or a theoretical covariance matrix, and a major argume... (Source: Genetics Selection Evolution)
Source: Genetics Selection Evolution - September 23, 2022 Category: Genetics & Stem Cells Authors: Rodolfo J. C. Cantet, Belcy K. Angarita-Barajas, Natalia S. Forneris and Sebasti án Munilla Tags: Research Article Source Type: research
Optimization of alternative breeding schemes for the genetic improvement of common Tigray highland sheep in northern Ethiopia
The objective of the current... (Source: Genetics Selection Evolution)
Source: Genetics Selection Evolution - September 16, 2022 Category: Genetics & Stem Cells Authors: Kiflay Welday Haileselassie, Solomon Abgaz Kebede, Mengistu Ugre Letta and Solomon Gizaw GebreMichael Tags: Research Article Source Type: research
Integration of multi-omics data reveals cis-regulatory variants that are associated with phenotypic differentiation of eastern from western pigs
The genetic mechanisms that underlie phenotypic differentiation in breeding animals have important implications in evolutionary biology and agriculture. However, the contribution of cis-regulatory variants to ... (Source: Genetics Selection Evolution)
Source: Genetics Selection Evolution - September 14, 2022 Category: Genetics & Stem Cells Authors: Yuwen Liu, Yang Fu, Yalan Yang, Guoqiang Yi, Jinmin Lian, Bingkun Xie, Yilong Yao, Muya Chen, Yongchao Niu, Lei Liu, Liyuan Wang, Yongsheng Zhang, Xinhao Fan, Yijie Tang, Pengxiang Yuan, Min Zhu & hellip; Tags: Research Article Source Type: research
Genetics of the phenotypic evolution in sheep: a molecular look at diversity-driving genes
After domestication, the evolution of phenotypically-varied sheep breeds has generated rich biodiversity. This wide phenotypic variation arises as a result of hidden genomic changes that range from a single nu... (Source: Genetics Selection Evolution)
Source: Genetics Selection Evolution - September 9, 2022 Category: Genetics & Stem Cells Authors: Peter Kalds, Shiwei Zhou, Yawei Gao, Bei Cai, Shuhong Huang, Yulin Chen and Xiaolong Wang Tags: Review Source Type: research
Sharing of either phenotypes or genetic variants can increase the accuracy of genomic prediction of feed efficiency
Sharing individual phenotype and genotype data between countries is complex and fraught with potential errors, while sharing summary statistics of genome-wide association studies (GWAS) is relatively straightf... (Source: Genetics Selection Evolution)
Source: Genetics Selection Evolution - September 6, 2022 Category: Genetics & Stem Cells Authors: Sunduimijid Bolormaa, Iona M. MacLeod, Majid Khansefid, Leah C. Marett, William J. Wales, Filippo Miglior, Christine F. Baes, Flavio S. Schenkel, Erin E. Connor, Coralia I. V. Manzanilla-Pech, Paul Stothard, Emily Herman, Gert J. Nieuwhof, Michael E. Godd Tags: Research Article Source Type: research
Optimal experimental designs for estimating genetic and non-genetic effects underlying infectious disease transmission
The spread of infectious diseases in populations is controlled by the susceptibility (propensity to acquire infection), infectivity (propensity to transmit infection), and recoverability (propensity to recover... (Source: Genetics Selection Evolution)
Source: Genetics Selection Evolution - September 5, 2022 Category: Genetics & Stem Cells Authors: Christopher Pooley, Glenn Marion, Stephen Bishop and Andrea Doeschl-Wilson Tags: Research Article Source Type: research
