Systemic Sclerosis and Atherosclerosis: Potential Cellular Biomarkers and Mechanisms
Front Biosci (Schol Ed). 2023 Dec 26;15(4):16. doi: 10.31083/j.fbs1504016.ABSTRACTSystemic sclerosis (SSc) is a rare systemic autoimmune disease of unknown etiology, which is characterized by endothelial dysfunction, pathologic vasculopathy, and increased tissue fibrosis. Traditionally, SSc has been regarded as a prototypical fibrotic disease in the family of systemic autoimmune diseases. Traditionally, emphasis has been placed on the three components of the pathogenesis of SSc: vascular, immune, and mesenchymal. Microvascular lesions, including endothelial dysfunction and smooth muscle cell migration into the intima of ve...
Source: Frontiers in Bioscience - Scholar - January 2, 2024 Category: Biomedical Science Authors: Elena V Gerasimova Rushana U Shayakhmetova Daria A Gerasimova Tatiana V Popkova Lidia P Ananyeva Source Type: research

Identification of Candidate mRNA Genes and Their Potential MicroRNA Targets in Lung Cancer Induced by Smoking Tobacco
CONCLUSIONS: Our study found that the top five SSM-enriched mRNA proto-oncogenes in lung cancers among tobacco smokers were TP53, EGFR, KRAS, FAT4, and KMT2D. Further, our results provide an important insight into the involvement of the intricate network of mRNA-miRNA interactions in the development of lung cancer.PMID:38163953 | DOI:10.31083/j.fbs1504013 (Source: Frontiers in Bioscience - Scholar)
Source: Frontiers in Bioscience - Scholar - January 2, 2024 Category: Biomedical Science Authors: Amresh Kumar Mishra Neha Mumtaz Maneesh Kumar Misra Source Type: research

Fisetin Treats Kidney Oxidative Stress, Inflammation, and Apoptosis in Rat Diarrhea
CONCLUSIONS: Fisetin treated diarrhea in rats by restoring kidney function, antioxidant activity, inflammatory markers, apoptosis, proteome content, and histology.PMID:38163954 | DOI:10.31083/j.fbs1504014 (Source: Frontiers in Bioscience - Scholar)
Source: Frontiers in Bioscience - Scholar - January 2, 2024 Category: Biomedical Science Authors: Khaled M M Koriem Yousra K O Farouk Source Type: research

Characterization of the < em > Cambaroides wladiwostokiensis < /em > Birstein & amp; Vinogradov, 1934 (Decapoda: Astacidea) Mitochondrial Genome Using Genome Skimming and the Phylogenetic Implications within the Astacidea Infraorder
CONCLUSIONS: Collectively, these findings reveal variable sites and contribute to a deeper understanding of the genetic diversity in this genus alongside the further development of species-specific primers for noninvasive monitoring techniques. The partitioned phylogenetic analysis of Astacidea revealed a paraphyletic origin of Asian cambarids, which confirms the data in recent studies based on both multilocus analyses and integrative approaches.PMID:38163955 | DOI:10.31083/j.fbs1504015 (Source: Frontiers in Bioscience - Scholar)
Source: Frontiers in Bioscience - Scholar - January 2, 2024 Category: Biomedical Science Authors: Sergei V Turanov Evgeny I Barabanshchikov Source Type: research

Effect of 5-aminolevulinic Acid on Mitochondrial Activity
CONCLUSIONS: The results of this study can be used to develop a personalized therapeutic approach based on different mitochondrial activities.PMID:38163956 | DOI:10.31083/j.fbs1504017 (Source: Frontiers in Bioscience - Scholar)
Source: Frontiers in Bioscience - Scholar - January 2, 2024 Category: Biomedical Science Authors: Yuliya V Markina Alexander M Markin Tatiana V Kirichenko Taisiya V Tolstik Vadim R Cherednichenko Diana G Kiseleva Alexander N Orekhov Source Type: research

Systemic Sclerosis and Atherosclerosis: Potential Cellular Biomarkers and Mechanisms
Front Biosci (Schol Ed). 2023 Dec 26;15(4):16. doi: 10.31083/j.fbs1504016.ABSTRACTSystemic sclerosis (SSc) is a rare systemic autoimmune disease of unknown etiology, which is characterized by endothelial dysfunction, pathologic vasculopathy, and increased tissue fibrosis. Traditionally, SSc has been regarded as a prototypical fibrotic disease in the family of systemic autoimmune diseases. Traditionally, emphasis has been placed on the three components of the pathogenesis of SSc: vascular, immune, and mesenchymal. Microvascular lesions, including endothelial dysfunction and smooth muscle cell migration into the intima of ve...
Source: Frontiers in Bioscience - Scholar - January 2, 2024 Category: Biomedical Science Authors: Elena V Gerasimova Rushana U Shayakhmetova Daria A Gerasimova Tatiana V Popkova Lidia P Ananyeva Source Type: research

Identification of Candidate mRNA Genes and Their Potential MicroRNA Targets in Lung Cancer Induced by Smoking Tobacco
CONCLUSIONS: Our study found that the top five SSM-enriched mRNA proto-oncogenes in lung cancers among tobacco smokers were TP53, EGFR, KRAS, FAT4, and KMT2D. Further, our results provide an important insight into the involvement of the intricate network of mRNA-miRNA interactions in the development of lung cancer.PMID:38163953 | DOI:10.31083/j.fbs1504013 (Source: Frontiers in Bioscience - Scholar)
Source: Frontiers in Bioscience - Scholar - January 2, 2024 Category: Biomedical Science Authors: Amresh Kumar Mishra Neha Mumtaz Maneesh Kumar Misra Source Type: research

Fisetin Treats Kidney Oxidative Stress, Inflammation, and Apoptosis in Rat Diarrhea
CONCLUSIONS: Fisetin treated diarrhea in rats by restoring kidney function, antioxidant activity, inflammatory markers, apoptosis, proteome content, and histology.PMID:38163954 | DOI:10.31083/j.fbs1504014 (Source: Frontiers in Bioscience - Scholar)
Source: Frontiers in Bioscience - Scholar - January 2, 2024 Category: Biomedical Science Authors: Khaled M M Koriem Yousra K O Farouk Source Type: research

Characterization of the < em > Cambaroides wladiwostokiensis < /em > Birstein & amp; Vinogradov, 1934 (Decapoda: Astacidea) Mitochondrial Genome Using Genome Skimming and the Phylogenetic Implications within the Astacidea Infraorder
CONCLUSIONS: Collectively, these findings reveal variable sites and contribute to a deeper understanding of the genetic diversity in this genus alongside the further development of species-specific primers for noninvasive monitoring techniques. The partitioned phylogenetic analysis of Astacidea revealed a paraphyletic origin of Asian cambarids, which confirms the data in recent studies based on both multilocus analyses and integrative approaches.PMID:38163955 | DOI:10.31083/j.fbs1504015 (Source: Frontiers in Bioscience - Scholar)
Source: Frontiers in Bioscience - Scholar - January 2, 2024 Category: Biomedical Science Authors: Sergei V Turanov Evgeny I Barabanshchikov Source Type: research

Effect of 5-aminolevulinic Acid on Mitochondrial Activity
CONCLUSIONS: The results of this study can be used to develop a personalized therapeutic approach based on different mitochondrial activities.PMID:38163956 | DOI:10.31083/j.fbs1504017 (Source: Frontiers in Bioscience - Scholar)
Source: Frontiers in Bioscience - Scholar - January 2, 2024 Category: Biomedical Science Authors: Yuliya V Markina Alexander M Markin Tatiana V Kirichenko Taisiya V Tolstik Vadim R Cherednichenko Diana G Kiseleva Alexander N Orekhov Source Type: research

Systemic Sclerosis and Atherosclerosis: Potential Cellular Biomarkers and Mechanisms
Front Biosci (Schol Ed). 2023 Dec 26;15(4):16. doi: 10.31083/j.fbs1504016.ABSTRACTSystemic sclerosis (SSc) is a rare systemic autoimmune disease of unknown etiology, which is characterized by endothelial dysfunction, pathologic vasculopathy, and increased tissue fibrosis. Traditionally, SSc has been regarded as a prototypical fibrotic disease in the family of systemic autoimmune diseases. Traditionally, emphasis has been placed on the three components of the pathogenesis of SSc: vascular, immune, and mesenchymal. Microvascular lesions, including endothelial dysfunction and smooth muscle cell migration into the intima of ve...
Source: Frontiers in Bioscience - Scholar - January 2, 2024 Category: Biomedical Science Authors: Elena V Gerasimova Rushana U Shayakhmetova Daria A Gerasimova Tatiana V Popkova Lidia P Ananyeva Source Type: research

Identification of Candidate mRNA Genes and Their Potential MicroRNA Targets in Lung Cancer Induced by Smoking Tobacco
CONCLUSIONS: Our study found that the top five SSM-enriched mRNA proto-oncogenes in lung cancers among tobacco smokers were TP53, EGFR, KRAS, FAT4, and KMT2D. Further, our results provide an important insight into the involvement of the intricate network of mRNA-miRNA interactions in the development of lung cancer.PMID:38163953 | DOI:10.31083/j.fbs1504013 (Source: Frontiers in Bioscience - Scholar)
Source: Frontiers in Bioscience - Scholar - January 2, 2024 Category: Biomedical Science Authors: Amresh Kumar Mishra Neha Mumtaz Maneesh Kumar Misra Source Type: research

Fisetin Treats Kidney Oxidative Stress, Inflammation, and Apoptosis in Rat Diarrhea
CONCLUSIONS: Fisetin treated diarrhea in rats by restoring kidney function, antioxidant activity, inflammatory markers, apoptosis, proteome content, and histology.PMID:38163954 | DOI:10.31083/j.fbs1504014 (Source: Frontiers in Bioscience - Scholar)
Source: Frontiers in Bioscience - Scholar - January 2, 2024 Category: Biomedical Science Authors: Khaled M M Koriem Yousra K O Farouk Source Type: research

Characterization of the < em > Cambaroides wladiwostokiensis < /em > Birstein & amp; Vinogradov, 1934 (Decapoda: Astacidea) Mitochondrial Genome Using Genome Skimming and the Phylogenetic Implications within the Astacidea Infraorder
CONCLUSIONS: Collectively, these findings reveal variable sites and contribute to a deeper understanding of the genetic diversity in this genus alongside the further development of species-specific primers for noninvasive monitoring techniques. The partitioned phylogenetic analysis of Astacidea revealed a paraphyletic origin of Asian cambarids, which confirms the data in recent studies based on both multilocus analyses and integrative approaches.PMID:38163955 | DOI:10.31083/j.fbs1504015 (Source: Frontiers in Bioscience - Scholar)
Source: Frontiers in Bioscience - Scholar - January 2, 2024 Category: Biomedical Science Authors: Sergei V Turanov Evgeny I Barabanshchikov Source Type: research

Effect of 5-aminolevulinic Acid on Mitochondrial Activity
CONCLUSIONS: The results of this study can be used to develop a personalized therapeutic approach based on different mitochondrial activities.PMID:38163956 | DOI:10.31083/j.fbs1504017 (Source: Frontiers in Bioscience - Scholar)
Source: Frontiers in Bioscience - Scholar - January 2, 2024 Category: Biomedical Science Authors: Yuliya V Markina Alexander M Markin Tatiana V Kirichenko Taisiya V Tolstik Vadim R Cherednichenko Diana G Kiseleva Alexander N Orekhov Source Type: research