Adverse events associated with brolucizumab: a disproportionality analysis of the FDA adverse event reporting system (FAERS)
CONCLUSIONS: Several unexpected ocular and systemic AE signals associated with brolucizumab were identified through data mining of the FAERS database.PMID:38404234 | DOI:10.1080/14740338.2024.2322712 (Source: Expert Opinion on Drug Safety)
Source: Expert Opinion on Drug Safety - February 26, 2024 Category: Drugs & Pharmacology Authors: Xiaomei Xiong Xiuwen Zhang Xiaoxia Li Taomin Huang Source Type: research
Adverse events associated with brolucizumab: a disproportionality analysis of the FDA adverse event reporting system (FAERS)
Conclusions Several unexpected ocular and systemic AE signals associated with brolucizumab were identified through data mining of the FAERS database.PMID:38404234 | DOI:10.1080/14740338.2024.2322712 (Source: Expert Opinion on Drug Safety)
Source: Expert Opinion on Drug Safety - February 26, 2024 Category: Drugs & Pharmacology Authors: Xiaomei Xiong Xiuwen Zhang Xiaoxia Li Taomin Huang Source Type: research
Lessons learned from COVID-19, H1N1, and routine vaccine pharmacovigilance in the United States: a path to a more robust vaccine safety program
Expert Opin Drug Saf. 2024 Feb;23(2):161-175. doi: 10.1080/14740338.2024.2305707. Epub 2024 Feb 11.ABSTRACTINTRODUCTION: Vaccine pharmacovigilance is an essential component of vaccine safety programs. Vaccine pharmacovigilance refers to detecting uncommon adverse events following immunization (AEFI), determining whether they are due to the vaccine or are only a coincidence, and, for those AEFI considered related to vaccination, characterizing them further. When AEFI are due to vaccination, it is important to characterize the attributable risk and ascertain the biological mechanism causing the adverse reaction to inform eff...
Source: Expert Opinion on Drug Safety - February 12, 2024 Category: Drugs & Pharmacology Authors: Daniel A Salmon Robert T Chen Steve Black Joshua Sharfstein Source Type: research
Renal drug dosage adjustments and adverse drug events in patients with chronic kidney disease admitted to the hospital: a cross-sectional study
CONCLUSION: CKD patients are often prescribed medication dosages in disagreement with SmPC renal dosing recommendations. Besides explicit factors, treatment goals, feasibility of monitoring and alternative treatment must be weighed when assessing drug and dosage appropriateness. Gastrointestinal bleeding was the most frequent ADE that contributed to hospital admissions of CKD patients.PMID:38332533 | DOI:10.1080/14740338.2023.2295980 (Source: Expert Opinion on Drug Safety)
Source: Expert Opinion on Drug Safety - February 9, 2024 Category: Drugs & Pharmacology Authors: Zuzana O čovská Jana Proch ázková Martina Ma říková Ji ří Vlček Source Type: research
Anticancer drug-induced interstitial lung disease: a critical appraisal of clinical practice guidelines and consensus statements
Expert Opin Drug Saf. 2024 Feb 7. doi: 10.1080/14740338.2024.2315113. Online ahead of print.ABSTRACTAnticancer drug-induced interstitial lung disease (DIILD) has received increasing clinical attention, and the quality of relevant guidance documents has become critical. Our purpose was to assess the quality of documents for anticancer DIILD and summarize the recommendations. Clinical practice guidelines (CPGs) and consensus statements with recommendations for the evaluation, treatment, and monitoring of anticancer DIILD were searched in electronic databases, websites of guideline organizations, and professional societies. T...
Source: Expert Opinion on Drug Safety - February 7, 2024 Category: Drugs & Pharmacology Authors: Zhuo Ma Yi Zhang Ximu Sun Yuhui Zhang Min Zhu Shu Zhang Xin Feng Zhuoling An Source Type: research
