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The impact of pregnancy and associated hormones on the pharmacokinetics of Δ9-tetrahydrocannabinol
. (Source: Expert Opinion on Drug Metabolism and Toxicology)
Source: Expert Opinion on Drug Metabolism and Toxicology - March 4, 2024 Category: Drugs & Pharmacology Authors: Aurora K. AuthementNina IsoherranenDepartment of Pharmaceutics, School of Pharmacy, University of Washington, Seattle, WA, USA Source Type: research

Comparison of pharmacokinetic properties of alteplase and tenecteplase. The future of thrombolysis in acute ischemic stroke
. (Source: Expert Opinion on Drug Metabolism and Toxicology)
Source: Expert Opinion on Drug Metabolism and Toxicology - February 29, 2024 Category: Drugs & Pharmacology Authors: Alessandro Mar èSimone LorenzutFrancesco JanesCarolina GentileRoberto MarinigYan TereshkoGian Luigi GigliMariarosaria ValenteGiovanni Merlinoa Clinical Neurology, Department of Head, Neck and Neurosciences, Udine University Hospital, Udine, Italyb Stroke Source Type: research

Hepatotoxicity of newer antiseizure medications in children: an overview and disproportionality analysis of VigiBase
. (Source: Expert Opinion on Drug Metabolism and Toxicology)
Source: Expert Opinion on Drug Metabolism and Toxicology - February 28, 2024 Category: Drugs & Pharmacology Authors: Sanja Petrovi ćMilena KovačevićSandra Vezmar KovačevićBranislava Miljkovića PrimeVigilance d.o.o, Belgrade, Serbiab Department of Pharmacokinetics and Clinical Pharmacy, University of Belgrade – Pharmacy, Belgrade, Serbia Source Type: research

Exploring the level of agreement among different drug-drug interaction checkers: a comparative study on direct oral anticoagulants
. (Source: Expert Opinion on Drug Metabolism and Toxicology)
Source: Expert Opinion on Drug Metabolism and Toxicology - February 27, 2024 Category: Drugs & Pharmacology Authors: Massimo CarolloSalvatore CrisafulliFrancesco CiccimarraGiuseppe And òIgor DiembergerGianluca Trifiròa Department of Diagnostics and Public Health, University of Verona, Verona, Italyb Department of Clinical and Experimental Medicine, University of Messi Source Type: research

Potential benefits and possible risks of CGRP-targeted multitherapy in migraine
. (Source: Expert Opinion on Drug Metabolism and Toxicology)
Source: Expert Opinion on Drug Metabolism and Toxicology - February 7, 2024 Category: Drugs & Pharmacology Authors: Keiko IharaTsubasa TakizawaNarumi WatanabeJin NakaharaPaolo Martellettia Department of Neurology, Keio University School of Medicine, Tokyo, Japanb Japanese Red Cross Ashikaga Hospital, Ashikaga, Japanc School of Health Sciences, Unitelma Sapienza Univers Source Type: research

In-silico approaches to assessing multiple high-level drug-drug and drug-disease adverse drug effects
. (Source: Expert Opinion on Drug Metabolism and Toxicology)
Source: Expert Opinion on Drug Metabolism and Toxicology - February 1, 2024 Category: Drugs & Pharmacology Authors: Xuan XuJim E RiviereShahzad RazaNuwan Indika Millagaha GedaraRemya Ampadi RamachandranLisa A TellGerald J. WyckoffMajid Jaberi-Dourakia 1DATA Consortium, www.1DATA.life, Kansas State University Olathe, Olathe, KS, USAb Food Animal Residue Avoidance and Da Source Type: research

What is the risk of hepatotoxicity induced by immune-checkpoint inhibitors and how can we avoid it?
. (Source: Expert Opinion on Drug Metabolism and Toxicology)
Source: Expert Opinion on Drug Metabolism and Toxicology - February 1, 2024 Category: Drugs & Pharmacology Authors: Elisa TassinariMatteo RoselliniAndrea MarchettiVeronica MollicaFrancesco Massaria Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italyb Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, It Source Type: research

Chronic kidney disease and physiologically based pharmacokinetic modeling: a critical review of existing models
. (Source: Expert Opinion on Drug Metabolism and Toxicology)
Source: Expert Opinion on Drug Metabolism and Toxicology - January 25, 2024 Category: Drugs & Pharmacology Authors: Ammara ZamirFaleh AlqahtaniMuhammad Fawad Rasoola Department of Pharmacy Practice, Pharmacy, Bahauddin Zakariya University, Multan, Pakistanb Department of Pharmacology and Toxicology, College of Pharmacy, King Saud Universi-ty, Riyadh, Saudi Arabia Source Type: research

Regulation of PXR in drug metabolism: chemical and structural perspectives
. (Source: Expert Opinion on Drug Metabolism and Toxicology)
Source: Expert Opinion on Drug Metabolism and Toxicology - January 22, 2024 Category: Drugs & Pharmacology Authors: Rebecca R. Florke GeeAndrew D. HuberTaosheng Chena Graduate School of Biomedical Sciences, St. Jude Children ’s Research Hospital, Memphis, TN, USAb Department of Chemical Biology and Therapeutics, St. Jude Children’s Research Hospital, Memphis, TN, U Source Type: research

Interindividual variability in statin pharmacokinetics and effects of drug transporters
. (Source: Expert Opinion on Drug Metabolism and Toxicology)
Source: Expert Opinion on Drug Metabolism and Toxicology - January 22, 2024 Category: Drugs & Pharmacology Authors: Takeshi HirotaIchiro IeiriDepartment of Pharmacy, Kyushu University Hospital, Fukuoka, Japan Source Type: research

Inositols in treating polycystic ovary syndrome and non-insulin dependent diabetes mellitus: now and the future
. (Source: Expert Opinion on Drug Metabolism and Toxicology)
Source: Expert Opinion on Drug Metabolism and Toxicology - January 16, 2024 Category: Drugs & Pharmacology Authors: Antonio Simone Lagan àSamuel H. MyersGianpiero ForteAntoine NaemHarald KrentelLeila AllahqoliIbrahim AlkatoutVittorio Unfera Unit of Obstetrics and Gynecology, “Paolo Giaccone” Hospital, Department of Health Promotion, Mother and Child Care, Internal Source Type: research

Pharmacokinetics and pharmacodynamics of antibody-drug conjugates for the treatment of patients with breast cancer
. (Source: Expert Opinion on Drug Metabolism and Toxicology)
Source: Expert Opinion on Drug Metabolism and Toxicology - January 12, 2024 Category: Drugs & Pharmacology Authors: Fran çois CherifiAngélique Da SilvaDiogo Martins-BrancoAhmad AwadaGuilherme Nader-Martaa Oncology Medicine Department, Institut Jules Bordet, Hôpital Universitaire de Bruxelles (HUB), Université Libre de Bruxelles (ULB), Brussels, Belgiumb Breast Canc Source Type: research

Toxic metabolites and metabolic soft spots of celastrol based on glutathione metabolic capture and high-resolution mass spectrometry
. (Source: Expert Opinion on Drug Metabolism and Toxicology)
Source: Expert Opinion on Drug Metabolism and Toxicology - December 25, 2023 Category: Drugs & Pharmacology Authors: Xiaojuan JiangCaixia YuanRong DingDi LuXiaoyu PengZhihao DongChunyan ZhuYihua LinCaisheng WuQiang Xiea Fujian Provincial Key Laboratory of Innovative Drug Target Research and State Key Laboratory of Cell Stress Biology, School of Pharmaceutical Sciences, Source Type: research