Careful monitoring of fetal growth and maternal nutritional status should be practiced in pregnant women with a history of bariatric surgery
Commentary on: Chevrot A, Kayem G, Coupaye M, et al.. Impact of bariatric surgery on fetal growth restriction: experience of a perinatal and bariatric surgery center. Am J Obstet Gynecol 2016;214:655.e1–7 . Context The proportion of pregnancies after bariatric surgery has been increasing in the last few decades and in some countries they now constitute around 1% of annual deliveries.1 2 Maternal obesity is associated with several adverse pregnancy outcomes such as gestational diabetes, preterm birth, stillbirth and macrosomia. Theoretically, weight loss prior to pregnancy would reduce such risks. This appears to be t...
Source: Evidence-Based Medicine - November 22, 2016 Category: Internal Medicine Authors: Neovius, M., Stephansson, O. Tags: Epidemiologic studies, Diet, Obesity (nutrition), Pregnancy, Diabetes, Health education Aetiology/Harm Source Type: research
Low-dose second-generation oral contraceptives are associated with the lowest increased risk of cardiovascular adverse effects
Commentary on: Weill A, Dalichampt M, Raguideau F, et al.. Low dose oestrogen combined oral contraception and risk of pulmonary embolism, stroke, and myocardial infarction in five million French women: cohort study. BMJ 2016;353:i2002 . Context Oral contraceptives (OCs) are associated with an increased risk of cardiovascular disease. The association varies depending on whether the cardiovascular disease is arterial or venous and with varying progestogens and dosages of the oestrogen compound ethinyloestradiol. A recent Cochrane review concluded that OCs with the progestogens gestodene, desogestrel, cyproterone acetate or d...
Source: Evidence-Based Medicine - November 22, 2016 Category: Internal Medicine Authors: Lokkegaard, E. Tags: Health policy, Epidemiologic studies, Drugs: cardiovascular system, Stroke, Hypertension, Contraception, Drugs: obstetrics and gynaecology, Pregnancy, Ischaemic heart disease, Venous thromboembolism, Pulmonary embolism Aetiology/Harm Source Type: research
Implementing evidence-based practices improves neonatal outcomes
In this study, the authors prospectively examined a large cohort of infants (n=7336) born preterm (between 24+0 and 31+6 weeks gestational age) in 335 maternity units and admitted to 242 neonatal units across 19 regions in 11 European... (Source: Evidence-Based Medicine)
Source: Evidence-Based Medicine - November 22, 2016 Category: Internal Medicine Authors: Lee, S. K. Tags: EBM Prognosis, Epidemiologic studies, Ophthalmology Source Type: research
Rate of epilepsy in people with autism and the rate of autism in people with epilepsy are high
Commentary on: Sundelin HE, Larsson H, Lichtenstein P, et al.. Autism and epilepsy: a population-based nationwide cohort study. Neurology 2016;87:192–7. Context Population-based studies can provide information on the risk of people with autism developing epilepsy. Examination of family members of individuals with epilepsy can also provide a likelihood of a genetic link between autism and epilepsy. Sundelin et al carried out a register-based population study aimed at providing HRs for those with autism (ASD, autism spectrum disorder) developing epilepsy, those with epilepsy having ASD and relatives of people with epil...
Source: Evidence-Based Medicine - November 22, 2016 Category: Internal Medicine Authors: Besag, F. M. C. Tags: EBM Prognosis, Epidemiologic studies, Epilepsy and seizures, Child and adolescent psychiatry Source Type: research
In individuals at intermediate risk for cardiovascular disease, treatment with rosuvastatin but not candesartan plus hydrochlorothiazide lowers cardiovascular disease event rates
Commentary on: Lonn EM, Bosch J, López-Jaramillo P, et al.. Blood-pressure lowering in intermediate-risk persons without cardiovascular disease. N Engl J Med 2016;374:2009–20 . Yusuf S, Bosch J, Dagenais G, et al. Cholesterol lowering in intermediate-risk persons without cardiovascular disease. N Engl J Med 2016;374:2021–31. Context Cardiovascular diseases (CVD) are the number one cause of death globally: more people die annually from CVDs than from any other cause.1 The incidence of CVD rises progressively with increasing blood pressure (BP) and with increasing levels of total and low density lipoprotei...
Source: Evidence-Based Medicine - November 22, 2016 Category: Internal Medicine Authors: LeFevre, M. Tags: Drugs: cardiovascular system, Pain (neurology), Stroke, Hypertension, Ischaemic heart disease Therapeutics/Prevention Source Type: research
