The Role of Stress Echocardiography in Valvular Heart Disease
We describe the current methodology and the evidence supporting these applications.Recent FindingsThe comprehensive stress echo assessment includes valve function (gradients and regurgitation), left ventricular global systolic and diastolic function, left atrial volume, pulmonary congestion, pulmonary arterial pressure, and right ventricular function, integrated with blood pressure response with cuff sphygmomanometer, chronotropic reserve with heart rate, and symptoms.SummaryRecent guidelines recommend the evaluation of asymptomatic severe or symptomatic non-severe mitral regurgitation or stenosis with exercise stress and ...
Source: Current Cardiology Reports - August 30, 2022 Category: Cardiology Source Type: research

Pericardiectomy and Pericardial Window for the Treatment of Pericardial Disease in the Contemporary Era
AbstractPurpose of ReviewTo summarize the contemporary practice of pericardiectomy and pericardial window. We discuss the indications, preoperative planning, procedural aspects, postprocedural management, and outcomes of each procedure.Recent FindingsSurgical approaches for the treatment of pericardial disease have been around even before the emergence of cardiopulmonary bypass. Since the forthcoming of cardiopulmonary bypass, there have been significant changes in the epidemiology and diagnostic approach of pericardial diseases as well as advancements in the surgical techniques and perioperative management used in the car...
Source: Current Cardiology Reports - August 27, 2022 Category: Cardiology Source Type: research

Eradicating Atherosclerosis: Should We Start Statins at Younger Ages and at Lower LDL-Cs
AbstractPurpose of ReviewGiven the increasing burden of cardiovascular disease, we review the literature for earlier initiation of statin therapy at younger ages and lower low-density lipoprotein cholesterol (LDL-C) levels, with the goal of preventing the development of atherosclerosis prior to clinical events.Recent FindingsThere is a rising prevalence of dyslipidemia among younger adults. Although guidelines offer recommendations for adults over 40, there is little guidance for the management of younger adults with moderately elevated LDL-C levels. Earlier and more aggressive statin use may slow progression, or even halt...
Source: Current Cardiology Reports - August 25, 2022 Category: Cardiology Source Type: research

Integrating Advanced Lipid Testing and Biomarkers in Assessment and Treatment
AbstractPurpose of ReviewOur ability to assess and stratify atherosclerotic disease risk in patients is evolving. Recent advances in advanced lipid testing have created opportunities for clinical application of novel biomarkers.Recent FindingsUntil recently, LDL-C has served largely as the singular biomarker of ASCVD and guide for decisions in treatment for high-risk groups. There are important evolutions in the measurement of LDL-C but even still, the pathogenesis of atherosclerosis and ASCVD is not solely driven by LDL-C. As atherosclerosis is driven by multiple complex pathways including inflammation, it is important to...
Source: Current Cardiology Reports - August 24, 2022 Category: Cardiology Source Type: research

Leveraging Healthcare System Data to Identify High-Risk Dyslipidemia Patients
We describe ways in which healthcare systems are generating real-world data related to dyslipidemia and how these data are being leveraged to improve patient care.Recent FindingsThe electronic medical record has emerged as a major source of clinical data, which alongside claims and pharmacy dispending data is enabling healthcare systems the ability to identify care gaps (underdiagnosis and undertreatment) in patients with dyslipidemia. Availability of this data also allows healthcare systems the ability to test and deliver interventions at the point-of-care.SummaryReal-world data possess great potential as a complement to ...
Source: Current Cardiology Reports - August 22, 2022 Category: Cardiology Source Type: research