Respiratory therapies for Amyotrophic Lateral Sclerosis: A state of the art review
Chron Respir Dis. 2023 Jan-Dec;20:14799731231175915. doi: 10.1177/14799731231175915.ABSTRACTAmyotrophic lateral sclerosis (ALS) is a neurodegenerative condition noteworthy for upper and lower motor neuron death. Involvement of respiratory motor neuron pools leads to progressive pathology. These impairments include decreases in neural activation and muscle coordination, progressive airway obstruction, weakened airway defenses, restrictive lung disease, increased risk of pulmonary infections, and weakness and atrophy of respiratory muscles. These neural, airway, pulmonary, and neuromuscular changes deteriorate integrated res...
Source: Chronic Respiratory Disease - May 23, 2023 Category: Respiratory Medicine Authors: Priscila Sales de Campos Wendy L Olsen James P Wymer Barbara K Smith Source Type: research

Respiratory therapies for Amyotrophic Lateral Sclerosis: A state of the art review
Chron Respir Dis. 2023 Jan-Dec;20:14799731231175915. doi: 10.1177/14799731231175915.ABSTRACTAmyotrophic lateral sclerosis (ALS) is a neurodegenerative condition noteworthy for upper and lower motor neuron death. Involvement of respiratory motor neuron pools leads to progressive pathology. These impairments include decreases in neural activation and muscle coordination, progressive airway obstruction, weakened airway defenses, restrictive lung disease, increased risk of pulmonary infections, and weakness and atrophy of respiratory muscles. These neural, airway, pulmonary, and neuromuscular changes deteriorate integrated res...
Source: Chronic Respiratory Disease - May 23, 2023 Category: Respiratory Medicine Authors: Priscila Sales de Campos Wendy L Olsen James P Wymer Barbara K Smith Source Type: research

Respiratory therapies for Amyotrophic Lateral Sclerosis: A state of the art review
Chron Respir Dis. 2023 Jan-Dec;20:14799731231175915. doi: 10.1177/14799731231175915.ABSTRACTAmyotrophic lateral sclerosis (ALS) is a neurodegenerative condition noteworthy for upper and lower motor neuron death. Involvement of respiratory motor neuron pools leads to progressive pathology. These impairments include decreases in neural activation and muscle coordination, progressive airway obstruction, weakened airway defenses, restrictive lung disease, increased risk of pulmonary infections, and weakness and atrophy of respiratory muscles. These neural, airway, pulmonary, and neuromuscular changes deteriorate integrated res...
Source: Chronic Respiratory Disease - May 23, 2023 Category: Respiratory Medicine Authors: Priscila Sales de Campos Wendy L Olsen James P Wymer Barbara K Smith Source Type: research

Respiratory therapies for Amyotrophic Lateral Sclerosis: A state of the art review
Chron Respir Dis. 2023 Jan-Dec;20:14799731231175915. doi: 10.1177/14799731231175915.ABSTRACTAmyotrophic lateral sclerosis (ALS) is a neurodegenerative condition noteworthy for upper and lower motor neuron death. Involvement of respiratory motor neuron pools leads to progressive pathology. These impairments include decreases in neural activation and muscle coordination, progressive airway obstruction, weakened airway defenses, restrictive lung disease, increased risk of pulmonary infections, and weakness and atrophy of respiratory muscles. These neural, airway, pulmonary, and neuromuscular changes deteriorate integrated res...
Source: Chronic Respiratory Disease - May 23, 2023 Category: Respiratory Medicine Authors: Priscila Sales de Campos Wendy L Olsen James P Wymer Barbara K Smith Source Type: research

Respiratory therapies for Amyotrophic Lateral Sclerosis: A state of the art review
Chron Respir Dis. 2023 Jan-Dec;20:14799731231175915. doi: 10.1177/14799731231175915.ABSTRACTAmyotrophic lateral sclerosis (ALS) is a neurodegenerative condition noteworthy for upper and lower motor neuron death. Involvement of respiratory motor neuron pools leads to progressive pathology. These impairments include decreases in neural activation and muscle coordination, progressive airway obstruction, weakened airway defenses, restrictive lung disease, increased risk of pulmonary infections, and weakness and atrophy of respiratory muscles. These neural, airway, pulmonary, and neuromuscular changes deteriorate integrated res...
Source: Chronic Respiratory Disease - May 23, 2023 Category: Respiratory Medicine Authors: Priscila Sales de Campos Wendy L Olsen James P Wymer Barbara K Smith Source Type: research

Respiratory therapies for Amyotrophic Lateral Sclerosis: A state of the art review
Chron Respir Dis. 2023 Jan-Dec;20:14799731231175915. doi: 10.1177/14799731231175915.ABSTRACTAmyotrophic lateral sclerosis (ALS) is a neurodegenerative condition noteworthy for upper and lower motor neuron death. Involvement of respiratory motor neuron pools leads to progressive pathology. These impairments include decreases in neural activation and muscle coordination, progressive airway obstruction, weakened airway defenses, restrictive lung disease, increased risk of pulmonary infections, and weakness and atrophy of respiratory muscles. These neural, airway, pulmonary, and neuromuscular changes deteriorate integrated res...
Source: Chronic Respiratory Disease - May 23, 2023 Category: Respiratory Medicine Authors: Priscila Sales de Campos Wendy L Olsen James P Wymer Barbara K Smith Source Type: research

Respiratory therapies for Amyotrophic Lateral Sclerosis: A state of the art review
Chron Respir Dis. 2023 Jan-Dec;20:14799731231175915. doi: 10.1177/14799731231175915.ABSTRACTAmyotrophic lateral sclerosis (ALS) is a neurodegenerative condition noteworthy for upper and lower motor neuron death. Involvement of respiratory motor neuron pools leads to progressive pathology. These impairments include decreases in neural activation and muscle coordination, progressive airway obstruction, weakened airway defenses, restrictive lung disease, increased risk of pulmonary infections, and weakness and atrophy of respiratory muscles. These neural, airway, pulmonary, and neuromuscular changes deteriorate integrated res...
Source: Chronic Respiratory Disease - May 23, 2023 Category: Respiratory Medicine Authors: Priscila Sales de Campos Wendy L Olsen James P Wymer Barbara K Smith Source Type: research

Respiratory therapies for Amyotrophic Lateral Sclerosis: A state of the art review
Chron Respir Dis. 2023 Jan-Dec;20:14799731231175915. doi: 10.1177/14799731231175915.ABSTRACTAmyotrophic lateral sclerosis (ALS) is a neurodegenerative condition noteworthy for upper and lower motor neuron death. Involvement of respiratory motor neuron pools leads to progressive pathology. These impairments include decreases in neural activation and muscle coordination, progressive airway obstruction, weakened airway defenses, restrictive lung disease, increased risk of pulmonary infections, and weakness and atrophy of respiratory muscles. These neural, airway, pulmonary, and neuromuscular changes deteriorate integrated res...
Source: Chronic Respiratory Disease - May 23, 2023 Category: Respiratory Medicine Authors: Priscila Sales de Campos Wendy L Olsen James P Wymer Barbara K Smith Source Type: research

Palliation, end of life care and ventilation withdrawal in neuromuscular disorders
CONCLUSIONS: The principles of palliative care are well suited to addressing the complex needs of patients with NMDs and should be considered early in the course of illness rather than limited to care at the end of life. Embedding relationships with specialist palliative care services as part of the wider neuromuscular multidisciplinary team can facilitate staff education and ensure timely referral when more complex palliative care problems arise.PMID:37199317 | PMC:PMC10201157 | DOI:10.1177/14799731231175911 (Source: Chronic Respiratory Disease)
Source: Chronic Respiratory Disease - May 18, 2023 Category: Respiratory Medicine Authors: Joanna Elverson Hayley Evans Felicity Dewhurst Source Type: research

Palliation, end of life care and ventilation withdrawal in neuromuscular disorders
CONCLUSIONS: The principles of palliative care are well suited to addressing the complex needs of patients with NMDs and should be considered early in the course of illness rather than limited to care at the end of life. Embedding relationships with specialist palliative care services as part of the wider neuromuscular multidisciplinary team can facilitate staff education and ensure timely referral when more complex palliative care problems arise.PMID:37199317 | DOI:10.1177/14799731231175911 (Source: Chronic Respiratory Disease)
Source: Chronic Respiratory Disease - May 18, 2023 Category: Respiratory Medicine Authors: Joanna Elverson Hayley Evans Felicity Dewhurst Source Type: research

Palliation, end of life care and ventilation withdrawal in neuromuscular disorders
CONCLUSIONS: The principles of palliative care are well suited to addressing the complex needs of patients with NMDs and should be considered early in the course of illness rather than limited to care at the end of life. Embedding relationships with specialist palliative care services as part of the wider neuromuscular multidisciplinary team can facilitate staff education and ensure timely referral when more complex palliative care problems arise.PMID:37199317 | DOI:10.1177/14799731231175911 (Source: Chronic Respiratory Disease)
Source: Chronic Respiratory Disease - May 18, 2023 Category: Respiratory Medicine Authors: Joanna Elverson Hayley Evans Felicity Dewhurst Source Type: research

Palliation, end of life care and ventilation withdrawal in neuromuscular disorders
CONCLUSIONS: The principles of palliative care are well suited to addressing the complex needs of patients with NMDs and should be considered early in the course of illness rather than limited to care at the end of life. Embedding relationships with specialist palliative care services as part of the wider neuromuscular multidisciplinary team can facilitate staff education and ensure timely referral when more complex palliative care problems arise.PMID:37199317 | DOI:10.1177/14799731231175911 (Source: Chronic Respiratory Disease)
Source: Chronic Respiratory Disease - May 18, 2023 Category: Respiratory Medicine Authors: Joanna Elverson Hayley Evans Felicity Dewhurst Source Type: research

Symptoms burden and rehabilitation preference after an episode of COVID-19: A patients survey
CONCLUSION: The survey responses indicated a significant symptom burden that may benefit from an intervention such as rehabilitation. Preferences for rehabilitation indicated that a face-to-face intervention was preferred by the majority, with a large proportion preferring digital intervention.PMID:37192536 | PMC:PMC10191828 | DOI:10.1177/14799731231177316 (Source: Chronic Respiratory Disease)
Source: Chronic Respiratory Disease - May 16, 2023 Category: Respiratory Medicine Authors: Munyra Alhotye Enya Daynes Charlotte Gerlis Sally J Singh Source Type: research

Symptoms burden and rehabilitation preference after an episode of COVID-19: A patients survey
CONCLUSION: The survey responses indicated a significant symptom burden that may benefit from an intervention such as rehabilitation. Preferences for rehabilitation indicated that a face-to-face intervention was preferred by the majority, with a large proportion preferring digital intervention.PMID:37192536 | DOI:10.1177/14799731231177316 (Source: Chronic Respiratory Disease)
Source: Chronic Respiratory Disease - May 16, 2023 Category: Respiratory Medicine Authors: Munyra Alhotye Enya Daynes Charlotte Gerlis Sally J Singh Source Type: research

Long-term mechanical ventilation and transitions in care: A narrative review
CONCLUSIONS: For successful transitions, the VAIs and their support network must be front-and-center. There should be a coordinated, systematic, and holistic plan (including a multi-disciplinary team), life-time follow-up, with bespoke consideration of jurisdiction and individual circumstances.PMID:37170874 | PMC:PMC10184211 | DOI:10.1177/14799731231176301 (Source: Chronic Respiratory Disease)
Source: Chronic Respiratory Disease - May 12, 2023 Category: Respiratory Medicine Authors: Lena Xiao Reshma Amin Mika Laura Nonoyama Source Type: research