Correction to: Association of IL-10-592 C > A /-1082 A > G and the TNFα -308 G > A with susceptibility to COVID-19 and clinical outcomes
(Source: BMC Medical Genomics)
Source: BMC Medical Genomics - February 26, 2024 Category: Genetics & Stem Cells Authors: Raghda E. Eldesouki, Rania M. Kishk, Noha M. Abd El-Fadeal, Rama I Mahran, Noha Kamel, Eman Riad, Nader Nemr, Safaa M. Kishk and Eman Abdel-Moemen Mohammed Tags: Correction Source Type: research
Identifying functional subtypes of IgA nephropathy based on three machine learning algorithms and WGCNA
IgA nephropathy (IgAN) is one of the most common primary glomerulonephritis, which is a significant cause of renal failure. At present, the classification of IgAN is often limited to pathology, and its molecul... (Source: BMC Medical Genomics)
Source: BMC Medical Genomics - February 23, 2024 Category: Genetics & Stem Cells Authors: Hongbiao Ren, Wenhua Lv, Zhenwei Shang, Liangshuang Li, Qi Shen, Shuai Li, Zerun Song, Xiangshu Cheng, Xin Meng, Rui Chen and Ruijie Zhang Tags: Research Source Type: research
lncRNA-MIAT rs9625066 polymorphism could be a potential biomarker for ischemic stroke
Ischemic stroke (IS) is a common and serious neurological condition that is highly fatal but so far no early diagnostic markers are available. Myocardial infarction-associated transcript (MIAT) is a long non-c... (Source: BMC Medical Genomics)
Source: BMC Medical Genomics - February 21, 2024 Category: Genetics & Stem Cells Authors: Yin-Hua Weng, Jie Chen, Wen-Tao Yu, Yan-Ping Luo, Chao Liu, Jun Yang and Hong-Bo Liu Tags: Research Source Type: research
Proteome-wide mendelian randomization investigates potential associations in heart failure and its etiology: emphasis on PCSK9
Heart failure (HF) is a prevalent clinical syndrome with diverse etiologies. It is crucial to identify novel therapeutic targets based on underlying causes. Here, we aimed to use proteome-wide Mendelian random... (Source: BMC Medical Genomics)
Source: BMC Medical Genomics - February 21, 2024 Category: Genetics & Stem Cells Authors: Lichao Lin, Huizhen Yu, Yan Xue, Liman Wang and Pengli Zhu Tags: Research Source Type: research
Prognosis and biological function of SGOL1 in clear cell renal cell carcinoma: a multiomics analysis
Shugoshin-1 (SGOL1) is a mammalian ortholog of Shugoshin in yeast and is essential for precise chromosome segregation during mitosis and meiosis. Aberrant SGOL1 expression was reported to be closely correlated... (Source: BMC Medical Genomics)
Source: BMC Medical Genomics - February 21, 2024 Category: Genetics & Stem Cells Authors: Zezhong Yang, Yunzhong Jiang, Lu Wang, Binghe Yu, Hui Cai, Jinhai Fan and Mengzhao Zhang Tags: Research Source Type: research
Prenatal detection and molecular cytogenetic characterization of Xp deletion and Xq duplication: a case report and literature review
Copy number variation (CNV) of X chromosome can lead to a variety of neonatal abnormalities, especially for male fetuses. In recent years, due to the high sensitivity and high specificity of NIPS, its applicat... (Source: BMC Medical Genomics)
Source: BMC Medical Genomics - February 21, 2024 Category: Genetics & Stem Cells Authors: Qing Lin, Chunya Liang, Bole Du, Lijiao Li, Hong Li, Xiaolan Mai, Sheng Li, Wenyu Xu, Cunzhen Wu and Mi Zeng Tags: Case Report Source Type: research
Low frequency of SLC26A4 c.919-2A > G variant among patients with nonsyndromic hearing loss in Yunnan of Southwest China
Gene variants are responsible for more than half of hearing loss, particularly in nonsyndromic hearing loss (NSHL). The most common pathogenic variant in SLC26A4 gene found in East Asian populations is c.919-2A >... (Source: BMC Medical Genomics)
Source: BMC Medical Genomics - February 20, 2024 Category: Genetics & Stem Cells Authors: Yan-Qiong Li, Heng Ma, Qin-Yao Wang, De-Sheng Liu, Wei Wang, Shi-Xin Li, Rong-Xia Zuo, Tao Shen, Bao-Sheng Zhu and Ya-Lian Sa Tags: Research Source Type: research
Identification of functional genes in liver fibrosis based on bioinformatics analysis of a lncRNA-mediated ceRNA network
This study aimed to build a lncRNA-miRNA-mRNA network, identify potentially related lncRNAs, an... (Source: BMC Medical Genomics)
Source: BMC Medical Genomics - February 20, 2024 Category: Genetics & Stem Cells Authors: Feng Zhang, Siya Pei and Meifang Xiao Tags: Research Source Type: research
Genetic analysis of a pedigree with MECP2 duplication syndrome in China
MECP2 duplication syndrome (MDS) is a rare X-linked genomic disorder that primarily affects males. It is characterized by delayed or absent speech development, severe motor and cognitive impairment, and recurrent... (Source: BMC Medical Genomics)
Source: BMC Medical Genomics - February 19, 2024 Category: Genetics & Stem Cells Authors: Lan Zeng, Hui Zhu, Jin Wang, Qiyan Wang, Ying Pang, Zemin Luo, Ai Chen, Shengfang Qin and Shuyao Zhu Tags: Research Source Type: research
Molecular subtype identification and prognosis stratification based on golgi apparatus-related genes in head and neck squamous cell carcinoma
This study aims to investigate the po... (Source: BMC Medical Genomics)
Source: BMC Medical Genomics - February 16, 2024 Category: Genetics & Stem Cells Authors: Aichun Zhang, Xiao He, Chen Zhang and Xuxia Tang Tags: Research Source Type: research
Identification of diagnostic model in heart failure with myocardial fibrosis and conduction block by integrated gene co-expression network analysis
This study aims to investigate the genes related to myocardial fibros... (Source: BMC Medical Genomics)
Source: BMC Medical Genomics - February 14, 2024 Category: Genetics & Stem Cells Authors: Yonghua Yuan, Yiwei Niu, Jiajun Ye, Yuejuan Xu, Xuehua He and Sun Chen Tags: Research Source Type: research
Broadening the phenotype and genotype spectrum of novel mutations in pontocerebellar hypoplasia with a comprehensive molecular literature review
Pontocerebellar hypoplasia is an umbrella term describing a heterogeneous group of prenatal neurodegenerative disorders mostly affecting the pons and cerebellum, with 17 types associated with 25 genes. However... (Source: BMC Medical Genomics)
Source: BMC Medical Genomics - February 13, 2024 Category: Genetics & Stem Cells Authors: Mohammad-Reza Ghasemi, Sahand Tehrani Fateh, Aysan Moeinafshar, Hossein Sadeghi, Parvaneh Karimzadeh, Reza Mirfakhraie, Mitra Rezaei, Farzad Hashemi-Gorji, Morteza Rezvani Kashani, Fatemehsadat Fazeli Bavandpour, Saman Bagheri, Parinaz Moghimi, Masoumeh R Tags: Research Source Type: research
RNA sequencing reveals differential long noncoding RNA expression profiles in bacterial and viral meningitis in children
We aimed to investigate the involvement of long non-coding RNA (lncRNA) in bacterial and viral meningitis in children. (Source: BMC Medical Genomics)
Source: BMC Medical Genomics - February 12, 2024 Category: Genetics & Stem Cells Authors: Xin Li, Suzhen Sun and Huifeng Zhang Tags: Research Source Type: research
Quantified pathway mutations associate epithelial-mesenchymal transition and immune escape with poor prognosis and immunotherapy resistance of head and neck squamous cell carcinoma
Pathway mutations have been calculated to predict the poor prognosis and immunotherapy resistance in head and neck squamous cell carcinoma (HNSCC). To uncover the unique markers predicting prognosis and immune... (Source: BMC Medical Genomics)
Source: BMC Medical Genomics - February 8, 2024 Category: Genetics & Stem Cells Authors: Yuhong Huang, Han Liu, Bo Liu, Xiaoyan Chen, Danya Li, Junyuan Xue, Nan Li, Lei Zhu, Liu Yang, Jing Xiao and Chao Liu Tags: Research Source Type: research
A systematic analysis of deep learning in genomics and histopathology for precision oncology
Digitized histopathological tissue slides and genomics profiling data are available for many patients with solid tumors. In the last 5 years, Deep Learning (DL) has been broadly used to extract clinically acti... (Source: BMC Medical Genomics)
Source: BMC Medical Genomics - February 5, 2024 Category: Genetics & Stem Cells Authors: Michaela Unger and Jakob Nikolas Kather Tags: Research Source Type: research
