Apoptosis and the FLIP and NF-kappa B proteins as pharmacodynamic criteria for biosimilar TNF-alpha antagonists
Paulo César Martins Urbano,1 Vanete Thomaz Soccol,1 Valderilio Feijó Azevedo2 1Biotechnology and Bioprocess Engineering Program, Federal University of Parana, Curitiba, Parana, Brazil; 2Hospital de Clínicas, Federal University of Parana, Curitiba, Parana, Brazil Abstract: Various criteria are necessary to assess the efficacy and safety of biological medications in order to grant companies the right to register these medications with the appropriate bodies that regulate their sale. The imminent expiration of the patents on reference biological products which block the cytokine TNF-α (tumor necros...
Source: Biologics: Targets and Therapy - July 30, 2014 Category: Biochemistry Tags: Biologics: Targets and Therapy Source Type: research
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Source: Biologics: Targets and Therapy - May 28, 2014 Category: Biochemistry Source Type: research
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Source: Biologics: Targets and Therapy - April 16, 2014 Category: Biochemistry Source Type: research
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