Use of anti-TNFs for difficult-to-treat
Thomsen SF, Sand FL (Source: Biologics: Targets and Therapy)
Source: Biologics: Targets and Therapy - November 5, 2015 Category: Biochemistry Source Type: research
Role of collagenase clostridium histolyticum in Peyronie & #39;s disease
(Source: Biologics: Targets and Therapy)
Source: Biologics: Targets and Therapy - September 29, 2015 Category: Biochemistry Tags: Biologics: Targets and Therapy Source Type: research
Role of collagenase clostridium histolyticum in Peyronie's disease
Taylor C Peak,1 Gregory C Mitchell,2 Faysal A Yafi,2 Wayne J Hellstrom2 1Department of Urology, Tulane University School of Medicine, 2Section of Andrology, Department of Urology, Tulane University School of Medicine, New Orleans, LA, USA Abstract: Peyronie's disease is a localized connective tissue disease characterized by an active, inflammatory phase and a stable, quiescent phase, with the eventual development of collagenous plaques within the tunica albuginea of the penis. Risk factors primarily associated with Peyronie's disease include Dupuytren's contracture, penile trauma, and family history. A variety...
Source: Biologics: Targets and Therapy - September 29, 2015 Category: Biochemistry Tags: Biologics: Targets and Therapy Source Type: research
Role of CCH in PD
Peak TC, Mitchell GC, Yafi FA, Hellstrom WJ (Source: Biologics: Targets and Therapy)
Source: Biologics: Targets and Therapy - September 28, 2015 Category: Biochemistry Source Type: research
Effect of mild aerobic training on the myocardium of mice with chronic Chagas disease
Conclusion: Our results suggest that low-intensity aerobic exercise acts on morphological and morphometric parameters of the left and right ventricles in mice infected with T. cruzi, reducing the changes caused by the organism and making the results comparable to those of the uninfected control group.Keywords: Chagas disease, myocardium, aerobic exercise, morphometry (Source: Biologics: Targets and Therapy)
Source: Biologics: Targets and Therapy - September 23, 2015 Category: Biochemistry Tags: Biologics: Targets and Therapy Source Type: research
Mild aerobic training in chronic Chagas disease
Preto E, Lima NEA, Simardi L, Fonseca FLA, Fragata Filho AA, Maifrino LBM (Source: Biologics: Targets and Therapy)
Source: Biologics: Targets and Therapy - September 22, 2015 Category: Biochemistry Source Type: research
Clinical utility of ramucirumab in advanced gastric cancer
Matthew MK Chan,1,2 Katrin M Sjoquist,1,3 John R Zalcberg4 1NHMRC Clinical Trials Centre, University of Sydney, Sydney, NSW, Australia; 2Department of Medical Oncology, Central Coast Cancer Centre, Gosford Hospital, Gosford, NSW, Australia; 3Cancer Care Centre, St George Hospital, Sydney, NSW, Australia; 4School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia Abstract: Gastric cancer is currently the third most common cause of cancer deaths worldwide. Prognosis remains poor with most patients presenting with advanced or metastatic disease. A better understanding of angiogenesis has l...
Source: Biologics: Targets and Therapy - September 22, 2015 Category: Biochemistry Tags: Biologics: Targets and Therapy Source Type: research
Ramucirumab in gastric cancer
Chan MMK, Sjoquist KM, Zalcberg JR (Source: Biologics: Targets and Therapy)
Source: Biologics: Targets and Therapy - September 22, 2015 Category: Biochemistry Source Type: research
Clinical utility and patient considerations in the use of ofatumumab in chronic lymphocytic leukemia
Anna Maria Frustaci, Alessandra Tedeschi, Paola Picardi, Roberto Cairoli, Marco MontilloDepartment of Hematology, Niguarda Cancer Center, Niguarda Ca' Granda Hospital, Milan, Italy Abstract: Treatment aim for chronic lymphocytic leukemia has been radically changed over the past years from providing only a palliative approach to reaching disease eradication and improving survival. Ofatumumab is a monoclonal humanized antibody with peculiar in vitro and in vivo properties, at present approved for double fludarabine and alemtuzumab refractory chronic lymphocytic leukemia. Its efficacy in this subset of patients, who typi...
Source: Biologics: Targets and Therapy - September 18, 2015 Category: Biochemistry Tags: Biologics: Targets and Therapy Source Type: research
Ofatumumab in CLL
Frustaci AM, Tedeschi A, Picardi P, Cairoli R, Montillo M (Source: Biologics: Targets and Therapy)
Source: Biologics: Targets and Therapy - September 17, 2015 Category: Biochemistry Source Type: research
Giant-cell tumor of bone: treatment options and role of denosumab
Arun S Singh,1 Neal S Chawla,2 Sant P Chawla2 1Sarcoma Service, Division of Hematology/Oncology, University of California, Los Angeles, 2Sarcoma Oncology Center, Santa Monica, CA, USA Abstract: Giant-cell tumor of bone is a rare, locally aggressive tumor that typically occurs in the bones of skeletally mature young adults in their second to fourth decades. Traditionally, surgery has been the mainstay of therapy for this disease, but the disease can recur even with optimal procedures. Furthermore, it may occur in locations where a surgical approach would be morbid. The maturation of the understanding of the role of the rec...
Source: Biologics: Targets and Therapy - July 14, 2015 Category: Biochemistry Tags: Biologics: Targets and Therapy Source Type: research
Denosumab for giant-cell tumor of bone
Singh AS, Chawla NS, Chawla SP (Source: Biologics: Targets and Therapy)
Source: Biologics: Targets and Therapy - July 13, 2015 Category: Biochemistry Source Type: research
Localization and upregulation of survivin in cancer health disparities: a clinical perspective
Salma Khan,1,2 Heather Ferguson Bennit,1,2 Malyn May Asuncion Valenzuela,1,2 David Turay,1,3 Carlos J Diaz Osterman,1,2 Ron B Moyron,1,2 Grace E Esebanmen,1,2 Arjun Ashok,1,2 Nathan R Wall1,2 1Department of Biochemistry, 2Center for Health Disparities and Molecular Medicine, 3Department of Anatomy, Loma Linda University School of Medicine, Loma Linda, CA, USA Abstract: Survivin is one of the most important members of the inhibitors of apoptosis protein family, as it is expressed in most human cancers but is absent in normal, differentiated tissues. Lending to its importance, survivin has proven associations with apoptosis...
Source: Biologics: Targets and Therapy - July 9, 2015 Category: Biochemistry Tags: Biologics: Targets and Therapy Source Type: research
Survivin in cancer health disparities
Khan S, Ferguson Bennit H, Asuncion Valenzuela MM, Turay D, Diaz Osterman CJ, Moyron RB, Esebanmen GE, Ashok A, Wall NR (Source: Biologics: Targets and Therapy)
Source: Biologics: Targets and Therapy - July 8, 2015 Category: Biochemistry Source Type: research
