Two cases of laryngeal edema caused by sublingual allergen immunotherapy
We report two cases of laryngeal edema as adverse reactions to sublingual immunotherapy, which could be continued due to a change in the administration method. Case 1 presents a 15-year-old male suspected to have had anaphylaxis due to the dust at the age of 6 years. He started treatment with Miticure® and developed laryngeal edema 30 minutes after taking the 10000JAU dose on the 10th day. laryngeal edema was treated with intravenous infusion. Case 2 presents a 48-year-old woman. She started treatment with Cidacure® and developed respiratory distress and laryngeal edema 1 hour after taking the 5000JAU dose on the 5th day...
Source: Arerugi - March 24, 2024 Category: Allergy & Immunology Authors: Yuki Maruyama Kojiro Hirano Eriko Sekino Sawa Kamimura Youichirou Narikawa Isao Suzaki Toshikazu Shimane Source Type: research

Two cases of allergic vulvovaginitis diagnosed by direct microscopic urine sediment examination
Arerugi. 2024;73(2):201-205. doi: 10.15036/arerugi.73.201.ABSTRACTCedar pollen is known as a typical allergen that causes various allergic symptoms in the nasal mucosa, conjunctiva, and skin. However, inflammation of the vulvar mucosa due to sensitization to cedar pollen is not well-known. We experienced two cases in which the detection of cedar pollen during microscopic urine sediment examination led to the diagnosis of allergic vulvovaginitis caused by cedar pollen. The cases involved a 4-year-old girl and a 10-year-old girl. In both cases, the patients presented with chief complaints of pruritis in the vulva and insomni...
Source: Arerugi - March 24, 2024 Category: Allergy & Immunology Authors: Shingo Abe Hiromi Ohtsubo Source Type: research

Is inhaled corticosteroid step-down recommended for adult asthma patients have been well controlled over the long term with moderate or high-dose inhaled corticosteroids?
Arerugi. 2024;73(2):206-212. doi: 10.15036/arerugi.73.206.ABSTRACTWe conducted a systematic review to examine whether step-down of inhaled corticosteroid (ICS) is recommended for adult patients with asthma have been well controlled with moderate or high-dose inhaled corticosteroids for more than 12 weeks. Seven randomized controlled trials were included. ICS step-down did not increase asthma exacerbations requiring systemic steroid therapy and hospitalization. There was no effect on respiratory function, asthma control, or QOL. No significant differences were observed in serious adverse events or steroid-related adverse ev...
Source: Arerugi - March 24, 2024 Category: Allergy & Immunology Authors: Naoki Okada Hiroki Kabata Yoshihito Tanaka Tetsuya Homma Sunao Mikura Source Type: research

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Arerugi. 2024;73(2):213-214. doi: 10.15036/arerugi.73.213.NO ABSTRACTPMID:38522937 | DOI:10.15036/arerugi.73.213 (Source: Arerugi)
Source: Arerugi - March 24, 2024 Category: Allergy & Immunology Source Type: research

(no title)
Arerugi. 2024;73(2):215-216. doi: 10.15036/arerugi.73.215.NO ABSTRACTPMID:38522938 | DOI:10.15036/arerugi.73.215 (Source: Arerugi)
Source: Arerugi - March 24, 2024 Category: Allergy & Immunology Source Type: research

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Arerugi. 2024;73(2):217-218. doi: 10.15036/arerugi.73.217.NO ABSTRACTPMID:38522939 | DOI:10.15036/arerugi.73.217 (Source: Arerugi)
Source: Arerugi - March 24, 2024 Category: Allergy & Immunology Source Type: research

Study of allergic disorders using mouse model
Arerugi. 2024;73(1):1-5. doi: 10.15036/arerugi.73.1.NO ABSTRACTPMID:38403694 | DOI:10.15036/arerugi.73.1 (Source: Arerugi)
Source: Arerugi - February 25, 2024 Category: Allergy & Immunology Authors: Satoshi Nunomura Source Type: research

Definition and diagnosis of refractory/severe asthma
Arerugi. 2024;73(1):11-13. doi: 10.15036/arerugi.73.11.NO ABSTRACTPMID:38403695 | DOI:10.15036/arerugi.73.11 (Source: Arerugi)
Source: Arerugi - February 25, 2024 Category: Allergy & Immunology Authors: Yasuhiro Gon Source Type: research

The innate immune network and therapeutic approaches in asthma
Arerugi. 2024;73(1):14-20. doi: 10.15036/arerugi.73.14.NO ABSTRACTPMID:38403696 | DOI:10.15036/arerugi.73.14 (Source: Arerugi)
Source: Arerugi - February 25, 2024 Category: Allergy & Immunology Authors: Rie Baba Hiroki Kabata Koichi Fukunaga Source Type: research

Prospects for the commitment of genetic big data to allergy medicine
Arerugi. 2024;73(1):21-25. doi: 10.15036/arerugi.73.21.NO ABSTRACTPMID:38403697 | DOI:10.15036/arerugi.73.21 (Source: Arerugi)
Source: Arerugi - February 25, 2024 Category: Allergy & Immunology Authors: Hideyasu Yamada Source Type: research

Advances in diagnosis and treatment in eosinophilic granulomatosis with polyangiitis (egpa)
Arerugi. 2024;73(1):26-33. doi: 10.15036/arerugi.73.26.NO ABSTRACTPMID:38403698 | DOI:10.15036/arerugi.73.26 (Source: Arerugi)
Source: Arerugi - February 25, 2024 Category: Allergy & Immunology Authors: Masami Taniguchi Yosuke Kamide Yuto Nakamura Kentaro Watai Yuma Fukutomi Kiyoshi Sekiya Source Type: research

A case of clinically amyopathic dermamyositis with interstitial lung disease showing two deteriorations in 4 years
We report the case of a 45-year-old man who was diagnosed with clinically amyopathic dermamyositis (CADM) and interstitial lung disease (ILD) after presenting with skin lesions typical of CADM and testing positive for anti-Melanoma Diferentiation-Associated gene 5 (anti-MDA5) anti-bodies. He was treated with a regimen including steroid pulse therapy, intravenous cyclophosphamide (IVCY), and calcineurin Inhibitor drug, which initially improved his ILD. However, three months post-treatment, the first deterioration of his conditions occurred, necessitating further administration of steroid pulse therapy and IVCY. After eight ...
Source: Arerugi - February 25, 2024 Category: Allergy & Immunology Authors: Takashi Yamane Tomoyuki Urata Source Type: research

The efficacy of bronchial thermoplasty in long-term maintenance of adult patients with moderate to severe asthma
CONCLUSION: From a risk-benefit perspective, there is insufficient evidence to support a recommendation of BT in adult patients with moderate to severe asthma.PMID:38403700 | DOI:10.15036/arerugi.73.40 (Source: Arerugi)
Source: Arerugi - February 25, 2024 Category: Allergy & Immunology Authors: Takahiro Matsuyama Jun Tanaka Kazuya Tone Kaoruko Shimizu Takako Nakano Koichiro Takahashi Source Type: research

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Arerugi. 2024;73(1):52-53. doi: 10.15036/arerugi.73.52.NO ABSTRACTPMID:38403701 | DOI:10.15036/arerugi.73.52 (Source: Arerugi)
Source: Arerugi - February 25, 2024 Category: Allergy & Immunology Source Type: research

(no title)
Arerugi. 2024;73(1):54-55. doi: 10.15036/arerugi.73.54.NO ABSTRACTPMID:38403702 | DOI:10.15036/arerugi.73.54 (Source: Arerugi)
Source: Arerugi - February 25, 2024 Category: Allergy & Immunology Source Type: research