Effect of periostin in peri-implant sulcular fluid and gingival crevicular fluid: A comparative study
Conclusion: The present study analyzed periostin levels in gingival crevicular fluid obtained from patients diagnosed with periodontitis and sulcular fluid obtained from the sulcus around implants. Early biological markers or indicators of inflammation should be studied to determine the prognosis of treatment apart from the clinical assessment for the patient's benefit. (Source: Annals of African Medicine)
Source: Annals of African Medicine - November 9, 2023 Category: African Health Authors: VC Santhosh Karishma Anas Abdul Khader Varun Ramachandra Rohit Singh B Kaushik Shetty Vaishnavi Kailash Nimbalkar Source Type: research
Assessment of factors affecting response of direct-acting antivirals in chronic hepatitis C patients
Conclusions: DAAs are highly efficacious drugs in the treatment of CHC with a high rate of treatment response. Significant predictors of CHC treatment failure included comorbidities especially DM and HIV co-infection, IV drug abuse, presence of liver cirrhosis, thrombocytopenia, elevated transaminases, and previous treatment experience. However, independent predictors of treatment nonresponse observed in this study were thrombocytopenia, IV drug abuse, and liver cirrhosis.
Résumé
Contexte: Le virus de l'hépatite C (VHC) est un agent pathogène universellement r&#x...
Source: Annals of African Medicine - November 9, 2023 Category: African Health Authors: Nipun Jain Ravinder Garg Gagan Preet Singh Sarabjot Kaur Sumit Pal Singh Chawla Preeti Padda Source Type: research
Clinical presentation and macular morphology in retinitis pigmentosa patients
Conclusion: OCT provides information on macula structure in RP eyes. About 14.5% of eyes had a normal macula, while 85.5% had a maculopathy, confirming that RP eyes have a higher rate of maculopathy than non RP eyes. OCT evaluation of an RP eye should be a standard workup for the early detection of such maculopathy and monitoring for disease progression.
Résumé
Contexte: La tomographie par cohérence optique (OCT) est une technologie d'imagerie non invasive fréquemment utilisée qui permet une visualisation détaill�...
Source: Annals of African Medicine - November 9, 2023 Category: African Health Authors: Ogugua Ndubuisi Okonkwo Adekunle Olubola Hassan Chineze Thelma Agweye Umeh Victor Toyin Akanbi Source Type: research
Interleukin-6 and interleukin-8 levels in children with aplastic anemia and its correlation with disease severity and response to immunosuppressive therapy
Conclusions: Children with AA had higher IL-6 and IL-8 levels than normal age- and sex-matched controls. Increased levels were linked to the severity of the condition, suggesting that IL may have a role in AA. IL levels can be monitored in AA patients during IST, which can assist in predicting response to IST.
Résumé
Contexte: L'anémie aplastique (AA) est une affection peu fréquente caractérisée par une pancytopénie et une moelle osseuse hypocellulaire. Il a été démontré que l�...
Source: Annals of African Medicine - November 9, 2023 Category: African Health Authors: Anurag Singh Sharvan Kumar Bhargawa Geeta Yadav Rashmi Kushwaha Shailendra Prasad Verma Tanya Tripathi Uma Shankar Singh Anil Kumar Tripathi Source Type: research
Indications for echocardiography and confirmation rates of cardiovascular diseases: experience of a specialist cardiac outpatient clinic in Kumasi, Ghana
Conclusion: Echocardiography showed high confirmation rates for our patients with heart failure, VHD, and HHD. Prompt usage of this noninvasive cardiovascular imaging for the initial evaluation of patients with cardiovascular diseases is highly recommended.
Résumé
Contexte: L'échocardiographie transthoracique est une technique d'imagerie cardiovasculaire non invasive très utile pour le diagnostic et la stratification du risque dans la gestion des patients atteints de maladies cardiovasculaires. Notre objectif était d'examiner les...
Source: Annals of African Medicine - November 9, 2023 Category: African Health Authors: Yaw Amo Wiafe Emmanuel Acheamfour-Akowuah Isaac Kofi Owusu Source Type: research
Outcome of intramedullary nail coated with antibiotic-impregnated cement in chronic osteomyelitis
Conclusion: Antibiotic cement-coated nails are an effective method in local control of infection in Chr OM without any systemic side effect.
Résumé
Introduction: L'ostéomyélite chronique (OM Chr) peut résulter d'une infection hématogène aiguë ou de fractures ouvertes ou chirurgies orthopédiques. Parmi les diverses infections ostéoarticulaires, Chr OM est l'une des plus difficiles en termes de traitement. Dans le présent étude, nous éva...
Source: Annals of African Medicine - November 9, 2023 Category: African Health Authors: Pulak Sharma Anurag Baghel Source Type: research
COVID-19 pandemic fatigue among well-educated egyptian population: Cross-sectional study
Conclusions: Pandemic fatigue was observed after 7 to 10 months from the pandemic emergence even though the high education level of the participants.
Résumé
Objectif: L'étude explore l'émergence de la fatigue liée à la pandémie de COVID-19 chez les Égyptiens bien éduqués, mesurée en termes de niveau de respect des mesures de protection contre la COVID-19 pendant 20 mois depuis le début de la pandémie. Cadre et conception: Une coupe transversal &#...
Source: Annals of African Medicine - November 9, 2023 Category: African Health Authors: Gehan Fathy Balata Mona Samy Hamed Yousef Ahmed ElSherif Yara Mohamed Abuelmagd Source Type: research
Change in Prevalence and Pattern of Peptic Ulcer Disease in the Northern Savannah of Nigeria: An Endoscopic Study
Conclusion: The prevalence and pattern of PUD in Northern Savannah of Nigeria have changed – patients were predominantly male and older, and GU predominated.
Résumé
Fond: L'ulcère gastro-duodénal (UIP) est courant dans le monde entier. Son incidence et sa prévalence ont diminué ces dernières années dans les pays développés et une tendance similaire a été observée dans de nombreuses régions d'Afrique, y compris au Nigeria....
Source: Annals of African Medicine - November 9, 2023 Category: African Health Authors: Husain Yahya Source Type: research
Clinical profile, risk factors, and clinical outcomes in patients of venous thromboembolism at a tertiary care center
Conclusions: In our study of VTE patients, we have highlighted the possible risk factors, clinical presentation, and clinical outcomes to identify the disease early and help us initiate appropriate thromboprophylaxis to reduce morbidity.
Résumé
Contexte: Thromboembolie veineuse (TEV) se présente généralement comme une thrombose veineuse profonde (TVP) ou embolie pulmonaire (PE). Malgré les progrès rapides de ses modalités diagnostiques et thérapeutiques, il entraîne toujours une morbidité et...
Source: Annals of African Medicine - November 9, 2023 Category: African Health Authors: MA Khan Mohammed Mahaboob Pasha MN Arjun Narayanan Subramanian Source Type: research
Efficacy, safety, and public attitude toward COVID-19 vaccines: A systematic review
Conclusion: Several articles support the efficacy of COVID-19 vaccines, but general awareness and conception about them vary, including hesitancy, distrust, and some acceptance. Many factors affected the perception and attitude of people toward these vaccines. More clinical data on the efficacy and safety of COVID-19 vaccines should be generated to help boost confidence among users.
Résumé
Contexte: Cet article passe en revue une partie de la littérature sur l'innocuité et l'efficacité de différents vaccins COVID-19, les attitud...
Source: Annals of African Medicine - November 9, 2023 Category: African Health Authors: Blessing Osagumwendia Josiah Chinelo C Uzor Brontie A Duncan Emmanuel Chukwunwike Enebeli Ndidi Louis Otoboyor Source Type: research
Cerebral magnetic resonance imaging lesions in leigh syndrome are variegated
Annals of African Medicine 2023 22(3):402-403 (Source: Annals of African Medicine)
Source: Annals of African Medicine - July 4, 2023 Category: African Health Source Type: research
The paucity of pediatric emergency medicine fellowship training programs in Africa
Patrick Ovie FuetaAnnals of African Medicine 2023 22(3):399-401
Sub-Saharan Africa has the highest burden of childhood and adolescent mortality in the world. The leading causes of mortality in pediatric populations in Africa include preterm birth complications, pneumonia, malaria, diarrheal diseases, HIV/AIDS, and road injuries. These causes of childhood and adolescent mortality often lead to emergency room utilization due to critical presentation, placing emphasis on the importance of pediatric emergency services in Africa. Despite the criticality of pediatric emergency medicine (PEM) in the region, there is a paucity of...
Source: Annals of African Medicine - July 4, 2023 Category: African Health Authors: Patrick Ovie Fueta Source Type: research
Outcome of peripapillary polypoidal choroidal vasculopathy treatment using combination therapy intravitreal ranibizumab and thermal retinal laser photocoagulation
We present the case of a middle-aged female Nigerian diagnosed to have right eye peripapillary polypoidal choroidal vasculopathy (PCV). At presentation, her right eye Snellen visual acuity was 6/24+ (unaided) and 6/12 (aided) and the left eye was 6/9 (unaided) and 6/6 (aided). Fundus fluorescein angiography showed a hyperfluorescent peripapillary subretinal lesion associated with subretinal fluid demonstrated on spectral-domain optical coherence tomography. The PCV lesion was successfully treated using a combination of 3 monthly doses of intravitreal ranibizumab initially, followed by one session of focal therma...
Source: Annals of African Medicine - July 4, 2023 Category: African Health Authors: Ogugua Ndubuisi Okonkwo Toyin Akanbi Tolulope Odubela Martha-Mary Udoh Source Type: research
Psychosis following caffeine consumption in a young adolescent: Review of case and literature
Qadri Adebayo Adeleye, Chukwuma Melitus Attama, Odunanimen Egbeobauwaye, Onuorji AngelaAnnals of African Medicine 2023 22(3):392-394
Caffeine, a popular over-the-counter methylxanthine, is widely consumed for its potent psychoactive properties. Toxicity generally occurs with intentional overdose and is often multisystemic and life-threatening. Consumption by children is rarely planned, and safe doses are potentially toxic in them. A 12-year-old boy whose parents had denied him coffee on several occasions eventually had access to it. The caffeine dose ingested was sub-toxic although he developed severe and life-threatening...
Source: Annals of African Medicine - July 4, 2023 Category: African Health Authors: Qadri Adebayo Adeleye Chukwuma Melitus Attama Odunanimen Egbeobauwaye Onuorji Angela Source Type: research
Management Difficulties in the Coexistence of Covid-19 Infection and Diabetic Ketoacidosis (Case Report; Two Children with Newly Diagnosed Diabetes)
Fatma Özgüç Çömlek, Gülsüm SönmezAnnals of African Medicine 2023 22(3):388-391
Two 8-year-old girls were admitted to the emergency department with diabetic ketoacidosis (DKA) approximately 10 days apart. The patients with resistant severe acidosis and high infection parameters were diagnosed with COVID-19 by real-time reverse transcription-polymerase chain reaction test. Accompanying pneumonia was observed in one of the patients. Here, we aimed to discuss the difficulties in the management of patients with a new diagnosis of DKA with COVID-19 infection. In addition, ...
Source: Annals of African Medicine - July 4, 2023 Category: African Health Authors: Fatma Ö zg ü ç Ç ö mlek G ü ls ü m S ö nmez Source Type: research
