Identifying Prenatal Alcohol Exposure and Children Affected by It: A Review of Biomarkers and Screening Tools
CONCLUSIONS: Biomarkers and screening tools of PAE and its impact fall short of ideal predictive validity characteristics. Higher specificity than sensitivity was found for many of the biomarkers and screening tools used to identify PAE and its impact, suggesting that current methods continue to under-identify the full range of individuals impacted by PAE. Exceptions to this were found in recent investigations using microRNAs related to growth and vascular development, proteomic changes associated with PAE, and combinations of markers estimating levels of various cytokines. Replications of these findings are needed across ...
Source: Alcohol Research - June 1, 2023 Category: Addiction Authors: Julie A Kable Kenneth Lyons Jones Source Type: research
