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HTLV European Research Network 2023: the silent pandemic of HTLV-1 infection
AIDS Rev. 2023 Oct 26;25(3):147-149. doi: 10.24875/AIDSRev.M23000064.NO ABSTRACTPMID:37883995 | DOI:10.24875/AIDSRev.M23000064 (Source: AIDS Reviews)
Source: AIDS Reviews - October 26, 2023 Category: Infectious Diseases Authors: Carmen de Mendoza Ana Trevi ño Vicente Soriano Source Type: research

The impact of the M184V resistance mutation on treatment outcomes in patients with HIV infection: a systematic review and meta-analysis
AIDS Rev. 2023;26(3):136-144. doi: 10.24875/AIDSRev.23000002.ABSTRACTHIV is a global deliberating infectious disease. Of note, more than 36 million people living with HIV (PLHIV) with approximately newly diagnosed 1.5 million cases annually. M184V is a single base mutation in the highly conserved YMDD domain of reverse transcriptase (RT). It is one of the most encountered resistances associated with mutations to nucleoside RT inhibitors. There were continuous efforts to evaluate the impact of M184V mutation on the treatment outcomes in PLHIV. Therefore, the present systematic review was executed to reveal the virological f...
Source: AIDS Reviews - October 25, 2023 Category: Infectious Diseases Authors: Mahmoud Kandeel Source Type: research

Rebound in sexually transmitted infections after the COVID-19 pandemic
AIDS Rev. 2023;26(3):127-135. doi: 10.24875/AIDSRev.23000015.ABSTRACTSexually transmitted infections (STIs) have become the second in the global rating of infectious diseases after respiratory infections. Globally, over 1 million, new STI is diagnosed every day. Although four conditions are the most representative and of obligatory declaration (gonorrhea, syphilis, chlamydia, and human immunodeficiency virus [HIV]), there are many other prevalent STI, including trichomona, herpes simplex, papillomavirus, and viral hepatitis. Herein, we perform a narrative and retrospective review, analyzing information from public database...
Source: AIDS Reviews - October 25, 2023 Category: Infectious Diseases Authors: Vicente Soriano Hilario Blasco-Fontecilla Luc ía Gallego Jos é V Fernández-Montero Carmen de Mendoza Pablo Barreiro Source Type: research

Systematic review and meta-analysis of the global prevalence of sexually transmitted infections in people living with HIV and associated risk factors
This study was conducted to provide a summary of the evidence on the global prevalence of STIs in PLWH with an emphasis on infectious agents, diagnostic methods, and related risk factors. PubMed, Scopus, and Web of Science were systematically searched to include records published from January 01, 1990, to January 31, 2022, and the Google Scholar search engine was used to check the search strategy. In total, 132 eligible studies reporting STIs in PLWH were included, enrolling subjects from 35 countries across five continents. The pooled proportion of STIs was estimated to be 30.23% (95% CI, 26.1-34.45%) in PLWH and 20.01% (...
Source: AIDS Reviews - October 25, 2023 Category: Infectious Diseases Authors: Mina Ebrahimi Nayer Mehdizad Fatemeh Yeganeh-Sefidan Hanie Safarpour Abdol S Pagheh Amir Pouremamali Somayeh Shiralizadeh Ali Ghodrati Sana Jafari Firooz Shahrivar Siamak Heidarzadeh Mahboobeh Montazeri Mohammad Yousef-Memar Sonia M Rodrigues-Oliveira Mar Source Type: research

Mitochondrial damage as cause of long COVID
AIDS Rev. 2023;26(3):145-149. doi: 10.24875/AIDSRev.M23000063.NO ABSTRACTPMID:37879634 | DOI:10.24875/AIDSRev.M23000063 (Source: AIDS Reviews)
Source: AIDS Reviews - October 25, 2023 Category: Infectious Diseases Authors: Ilduara Pintos Vicente Soriano Source Type: research

Association between genital mycoplasmas (Ureaplasma urealyticum and Mycoplasma hominis) and HIV infection: a systematic review and meta-analysis
AIDS Rev. 2023;25(2):77-87. doi: 10.24875/AIDSRev.22000024.ABSTRACTSeveral studies have reported the occurrence of genital mycoplasmas (Ureaplasma urealyticum, Mycoplasma hominis, Mycoplasma genitalium, and Mycoplasma fermentans) among human immunodeficiency virus (HIV)-infected patients, but findings are conflicting. The aim of this systematic review and meta-analysis was to assess the association of U. urealyticum and M. hominis with HIV infection. We searched seven databases to retrieve articles reporting the prevalence of genital mycoplasmas among HIV-infected patients. Pooled odds ratios (OR) with 95% confidence inter...
Source: AIDS Reviews - August 16, 2023 Category: Infectious Diseases Authors: Safa Boujemaa Gurparsad Singh-Suri Gurleen Kaur Source Type: research

HIV patients' bone loss before and after antiretroviral treatment and its possible mechanisms
AIDS Rev. 2023;25(2):67-76. doi: 10.24875/AIDSRev.22000028.ABSTRACTHIV infection has been reported to cause bone loss and a higher risk of fracture. Under normal conditions, bone metabolism is regulated by mesenchymal cells, osteoclasts differentiated from mononuclear macrophages, osteoblasts, and their expression of regulatory factors, such as receptor activator of nuclear factor-kappa B ligand (RANKL), M-SCF, and transforming growth factor-beta. The balance between bone resorption and osteogenesis depends on the balance between osteoclasts and osteoblasts. In addition, some immune cells, such as B-cells, T-cells, and oth...
Source: AIDS Reviews - August 16, 2023 Category: Infectious Diseases Authors: Pei-Min Zheng Yu-Qing Xie Shi-Fan Lin Le Zou Zhi-Hua Huang Zhi-Ping Zhang Source Type: research