467 frailty in situ simulation
ConclusionIn-situ simulation is an effective tool for improving knowledge and confidence in managing frail patients. It increases awareness and understanding of human factors, which are key to the multidisciplinary approach frail patients require. The course is being expanded across the OPU and now has funding for a departmental manikin. The programme can be disseminated to other units to help improve the care and safety of those with frailty in hospital. (Source: Age and Ageing)
Source: Age and Ageing - June 12, 2021 Category: Geriatrics Source Type: research

513 the influence of frailty on outcomes for older adults admitted to hospital with benign biliary and pancreatic disease
ConclusionHalf of patients in our cohort of older adults hospitalised with acute biliary disease were frail. Higher scores of frailty are associated with increased mortality. Compared with non-frail patients, individuals living with frailty were less likely to undergo surgical treatment, spent longer in hospital and were less likely to remain alive at 12  months after hospital discharge. (Source: Age and Ageing)
Source: Age and Ageing - June 12, 2021 Category: Geriatrics Source Type: research

512 a case of an idiopathic acquired hemophilia a in an elderly woman
ConclusionThe diagnosis of acquired hemophilia should be considered in any elderly patient with prolonged APTT. Mixing study is to measure the presence of inhibitors of coagulation or to detect coagulation factor deficiency. Quantitative coagulation factor assays and Bethesda Assays are performed for definitive diagnosis. Immunosuppressive regimens are the mainstay treatment. However, premorbid conditions and co-morbidities should be taken into consideration before initiating the aggressive immunosuppressive therapy in the elderly patients. (Source: Age and Ageing)
Source: Age and Ageing - June 12, 2021 Category: Geriatrics Source Type: research

454 association between statins and major adverse cardiac events among older adults with frailty: a systematic review
This study identified only observational evidence that, among older people with frailty, statins are associated with reduced mortality when prescribed for secondary prevention, and an absence of evidence evaluating statin therapy for primary prevention. The findings of this study highlight that randomised trial data are urgently needed to better inform the use of statins among older adults living with frailty. (Source: Age and Ageing)
Source: Age and Ageing - June 12, 2021 Category: Geriatrics Source Type: research

451 the best marker for cognition —relative handgrip strength, asymmetry or weakness?
ConclusionOur study highlights the impact of ethnicity in sarcopenia research. Our population shows association of relative HGS with cognition. Further longitudinal studies are needed. (Source: Age and Ageing)
Source: Age and Ageing - June 12, 2021 Category: Geriatrics Source Type: research

576 ESTABLISHING VIRTUAL MULTIDISCIPLINARY ROUND IN BELFAST TRUST NURSING HOMES: PHARMACIST, NURSING & amp; HEALTHCARE TEAM COLLABORATION
ConclusionThe multidisciplinary care home rounds provided an efficient means to collaborate with other professionals, while providing holistic& patient-focussed care. Plans are underway for development of an NI MOOP care home pathway. (Source: Age and Ageing)
Source: Age and Ageing - June 12, 2021 Category: Geriatrics Source Type: research

532 caring for and caring about older people living with severe frailty during covid-19
ConclusionsThese are insights from hard-to-reach population that are frequently invisible. Greater examination of the impact of using communication technologies in care provision on those with poor access to and capabilities with using these technologies is required. Unpaid carers need more information and resources to support the care they provide and to facilitate access to appropriate social and health care services for those they care for. (Source: Age and Ageing)
Source: Age and Ageing - June 12, 2021 Category: Geriatrics Source Type: research

460 the impact of the bone mdt: exploring changes in bone protection decisions between 2015 and 2018
ConclusionsThere was a fall in bisphosphonate use and a significant increase in the frequency of denosumab prescription after the introduction of the Bone MDT. This MDT facilitated better decision-making through access to the further specialist skills from the endocrinologist and specialist nurses. Individual case discussion enhanced the delivery of personalised medicine. (Source: Age and Ageing)
Source: Age and Ageing - June 12, 2021 Category: Geriatrics Source Type: research

466 prevalence and impact of frailty in patients hospitalised with covid-19. the salford experience in waves 1 and 2
ConclusionFrailty is highly prevalent amongst patients of all ages admitted to SRFT with COVID-19. Higher scores of frailty are associated with increased mortality. (Source: Age and Ageing)
Source: Age and Ageing - June 12, 2021 Category: Geriatrics Source Type: research

457 nutrition, sarcopenia and frailty
ConclusionFrail older adults are often undernourished on admission to hospital. Nutritional intake is often poor with acute illness. Screening, observation and monitoring of nutritional intake should highlight concerns and needs for intervention. These study high lights that a significant number of older people are frail, fail to complete meals, are at significant risk of under nutrition, yet proactive intervention does not occur. (Source: Age and Ageing)
Source: Age and Ageing - June 12, 2021 Category: Geriatrics Source Type: research

505 interleukin-6, c-reactive protein, fibrinogen, and risk of recurrence after ischemic stroke: systematic review and meta-analysis
ConclusionDespite evidence suggesting an association between inflammatory markers and post-stroke vascular recurrence, substantial methodological heterogeneity was apparent between studies. Individual-patient pooled analysis and standardisation of methods are needed to determine the prognostic role of blood inflammatory markers and to improve patient selection for randomised trials of inflammatory therapies. (Source: Age and Ageing)
Source: Age and Ageing - June 12, 2021 Category: Geriatrics Source Type: research

494 discomfort in people with dementia admitted to an acute general medical hospital: a hospital cross sectional study of prevalence
ConclusionDiscomfort and challenging behaviours were very common in PwD admitted to acute hospitals. Patients and staff would benefit from more accurate and frequent detection of discomfort by focusing on non-pain-related discomfort and using observational scales. (Source: Age and Ageing)
Source: Age and Ageing - June 12, 2021 Category: Geriatrics Source Type: research

601 improving delirium assessment in a district general hospital
ConclusionOur journey to embed the 4AT is ongoing and we will continue to improve uptake using QI methodology. (Source: Age and Ageing)
Source: Age and Ageing - June 12, 2021 Category: Geriatrics Source Type: research

533 readmissions to geriatric medicine in a district general hospital, a thematic analysis
ConclusionWe found that delirium identification was a key factor in early readmissions to our service. We identified clear opportunities to strengthen and formalise delirium diagnoses, and better plan patient management and discharge plans as a result. A multidisciplinary quality improvement group looking at delirium has been initiated and has already achieved a statistically significant improvement in the use of 4AT, a delirium assessment tool. (Source: Age and Ageing)
Source: Age and Ageing - June 12, 2021 Category: Geriatrics Source Type: research

Author Index
(Source: Age and Ageing)
Source: Age and Ageing - June 12, 2021 Category: Geriatrics Source Type: research