Significance of the plasma membrane H < sup > + < /sup > -ATPase and V-ATPase for growth and pathogenicity in pathogenic fungi
Adv Appl Microbiol. 2023;124:31-53. doi: 10.1016/bs.aambs.2023.07.001. Epub 2023 Jul 28.ABSTRACTPathogenic fungi are widespread and cause a variety of diseases in human beings and other organisms. At present, limited classes of antifungal agents are available to treat invasive fungal diseases. With the wide use of the commercial antifungal agents, drug resistance of pathogenic fungi are continuously increasing. Therefore, exploring effective antifungal agents with novel drug targets is urgently needed to cope with the challenges that the antifungal area faces. pH homeostasis is vital for multiple cellular processes, reveal...
Source: Advances in Applied Microbiology - August 19, 2023 Category: Microbiology Authors: S Z Yang L T Peng Source Type: research
Halotolerance mechanisms in salt ‑tolerant cyanobacteria
Adv Appl Microbiol. 2023;124:55-117. doi: 10.1016/bs.aambs.2023.07.003. Epub 2023 Jul 23.ABSTRACTCyanobacteria are ubiquitously distributed in nature and are the most abundant photoautotrophs on Earth. Their long evolutionary history reveals that cyanobacteria have a remarkable capacity and strong adaptive tendencies to thrive in a variety of conditions. Thus, they can survive successfully, especially in harsh environmental conditions such as salty environments, high radiation, or extreme temperatures. Among others, salt stress because of excessive salt accumulation in salty environments, is the most common abiotic stress ...
Source: Advances in Applied Microbiology - August 19, 2023 Category: Microbiology Authors: Hakuto Kageyama Rungaroon Waditee-Sirisattha Source Type: research
Promoters and introns as key drivers for enhanced gene expression in Saccharomyces cerevisiae
Adv Appl Microbiol. 2023;124:1-29. doi: 10.1016/bs.aambs.2023.07.002. Epub 2023 Jul 27.ABSTRACTThe transcription of genes in the yeast Saccharomyces cerevisiae is governed by multiple layers of regulatory elements and proteins, cooperating to ensure optimum expression of the final protein product based on the cellular requirements. Promoters have always been regarded as the most important determinant of gene transcription, but introns also play a key role in the expression of intron-encoding genes. Some introns can enhance transcription when introduced either promoter-proximal or embedded in the open reading frame of genes...
Source: Advances in Applied Microbiology - August 19, 2023 Category: Microbiology Authors: Marthinus Wessel Myburgh Kirstie Susan Schwerdtfeger Rosemary Anne Cripwell Willem Heber van Zyl Marinda Viljoen-Bloom Source Type: research
From methane to value-added bioproducts: microbial metabolism, enzymes, and metabolic engineering
Adv Appl Microbiol. 2023;124:119-146. doi: 10.1016/bs.aambs.2023.07.004. Epub 2023 Jul 21.ABSTRACTMethane is abundant in nature, and excessive emissions will cause the greenhouse effect. Methane is also an ideal carbon and energy feedstock for biosynthesis. In the review, the microorganisms, metabolism, and enzymes for methane utilization, and the advances of conversion to value-added bioproducts were summarized. First, the physiological characteristics, classification, and methane oxidation process of methanotrophs were introduced. The metabolic pathways for methane utilization and key intermediate metabolites of native a...
Source: Advances in Applied Microbiology - August 19, 2023 Category: Microbiology Authors: Caihong Weng Xiaowei Peng Yejun Han Source Type: research
Significance of the plasma membrane H < sup > + < /sup > -ATPase and V-ATPase for growth and pathogenicity in pathogenic fungi
Adv Appl Microbiol. 2023;124:31-53. doi: 10.1016/bs.aambs.2023.07.001. Epub 2023 Jul 28.ABSTRACTPathogenic fungi are widespread and cause a variety of diseases in human beings and other organisms. At present, limited classes of antifungal agents are available to treat invasive fungal diseases. With the wide use of the commercial antifungal agents, drug resistance of pathogenic fungi are continuously increasing. Therefore, exploring effective antifungal agents with novel drug targets is urgently needed to cope with the challenges that the antifungal area faces. pH homeostasis is vital for multiple cellular processes, reveal...
Source: Advances in Applied Microbiology - August 19, 2023 Category: Microbiology Authors: S Z Yang L T Peng Source Type: research
Halotolerance mechanisms in salt ‑tolerant cyanobacteria
Adv Appl Microbiol. 2023;124:55-117. doi: 10.1016/bs.aambs.2023.07.003. Epub 2023 Jul 23.ABSTRACTCyanobacteria are ubiquitously distributed in nature and are the most abundant photoautotrophs on Earth. Their long evolutionary history reveals that cyanobacteria have a remarkable capacity and strong adaptive tendencies to thrive in a variety of conditions. Thus, they can survive successfully, especially in harsh environmental conditions such as salty environments, high radiation, or extreme temperatures. Among others, salt stress because of excessive salt accumulation in salty environments, is the most common abiotic stress ...
Source: Advances in Applied Microbiology - August 19, 2023 Category: Microbiology Authors: Hakuto Kageyama Rungaroon Waditee-Sirisattha Source Type: research
Promoters and introns as key drivers for enhanced gene expression in Saccharomyces cerevisiae
Adv Appl Microbiol. 2023;124:1-29. doi: 10.1016/bs.aambs.2023.07.002. Epub 2023 Jul 27.ABSTRACTThe transcription of genes in the yeast Saccharomyces cerevisiae is governed by multiple layers of regulatory elements and proteins, cooperating to ensure optimum expression of the final protein product based on the cellular requirements. Promoters have always been regarded as the most important determinant of gene transcription, but introns also play a key role in the expression of intron-encoding genes. Some introns can enhance transcription when introduced either promoter-proximal or embedded in the open reading frame of genes...
Source: Advances in Applied Microbiology - August 19, 2023 Category: Microbiology Authors: Marthinus Wessel Myburgh Kirstie Susan Schwerdtfeger Rosemary Anne Cripwell Willem Heber van Zyl Marinda Viljoen-Bloom Source Type: research
From methane to value-added bioproducts: microbial metabolism, enzymes, and metabolic engineering
Adv Appl Microbiol. 2023;124:119-146. doi: 10.1016/bs.aambs.2023.07.004. Epub 2023 Jul 21.ABSTRACTMethane is abundant in nature, and excessive emissions will cause the greenhouse effect. Methane is also an ideal carbon and energy feedstock for biosynthesis. In the review, the microorganisms, metabolism, and enzymes for methane utilization, and the advances of conversion to value-added bioproducts were summarized. First, the physiological characteristics, classification, and methane oxidation process of methanotrophs were introduced. The metabolic pathways for methane utilization and key intermediate metabolites of native a...
Source: Advances in Applied Microbiology - August 19, 2023 Category: Microbiology Authors: Caihong Weng Xiaowei Peng Yejun Han Source Type: research
Significance of the plasma membrane H < sup > + < /sup > -ATPase and V-ATPase for growth and pathogenicity in pathogenic fungi
Adv Appl Microbiol. 2023;124:31-53. doi: 10.1016/bs.aambs.2023.07.001. Epub 2023 Jul 28.ABSTRACTPathogenic fungi are widespread and cause a variety of diseases in human beings and other organisms. At present, limited classes of antifungal agents are available to treat invasive fungal diseases. With the wide use of the commercial antifungal agents, drug resistance of pathogenic fungi are continuously increasing. Therefore, exploring effective antifungal agents with novel drug targets is urgently needed to cope with the challenges that the antifungal area faces. pH homeostasis is vital for multiple cellular processes, reveal...
Source: Advances in Applied Microbiology - August 19, 2023 Category: Microbiology Authors: S Z Yang L T Peng Source Type: research
Halotolerance mechanisms in salt ‑tolerant cyanobacteria
Adv Appl Microbiol. 2023;124:55-117. doi: 10.1016/bs.aambs.2023.07.003. Epub 2023 Jul 23.ABSTRACTCyanobacteria are ubiquitously distributed in nature and are the most abundant photoautotrophs on Earth. Their long evolutionary history reveals that cyanobacteria have a remarkable capacity and strong adaptive tendencies to thrive in a variety of conditions. Thus, they can survive successfully, especially in harsh environmental conditions such as salty environments, high radiation, or extreme temperatures. Among others, salt stress because of excessive salt accumulation in salty environments, is the most common abiotic stress ...
Source: Advances in Applied Microbiology - August 19, 2023 Category: Microbiology Authors: Hakuto Kageyama Rungaroon Waditee-Sirisattha Source Type: research
Promoters and introns as key drivers for enhanced gene expression in Saccharomyces cerevisiae
Adv Appl Microbiol. 2023;124:1-29. doi: 10.1016/bs.aambs.2023.07.002. Epub 2023 Jul 27.ABSTRACTThe transcription of genes in the yeast Saccharomyces cerevisiae is governed by multiple layers of regulatory elements and proteins, cooperating to ensure optimum expression of the final protein product based on the cellular requirements. Promoters have always been regarded as the most important determinant of gene transcription, but introns also play a key role in the expression of intron-encoding genes. Some introns can enhance transcription when introduced either promoter-proximal or embedded in the open reading frame of genes...
Source: Advances in Applied Microbiology - August 19, 2023 Category: Microbiology Authors: Marthinus Wessel Myburgh Kirstie Susan Schwerdtfeger Rosemary Anne Cripwell Willem Heber van Zyl Marinda Viljoen-Bloom Source Type: research
From methane to value-added bioproducts: microbial metabolism, enzymes, and metabolic engineering
Adv Appl Microbiol. 2023;124:119-146. doi: 10.1016/bs.aambs.2023.07.004. Epub 2023 Jul 21.ABSTRACTMethane is abundant in nature, and excessive emissions will cause the greenhouse effect. Methane is also an ideal carbon and energy feedstock for biosynthesis. In the review, the microorganisms, metabolism, and enzymes for methane utilization, and the advances of conversion to value-added bioproducts were summarized. First, the physiological characteristics, classification, and methane oxidation process of methanotrophs were introduced. The metabolic pathways for methane utilization and key intermediate metabolites of native a...
Source: Advances in Applied Microbiology - August 19, 2023 Category: Microbiology Authors: Caihong Weng Xiaowei Peng Yejun Han Source Type: research
Significance of the plasma membrane H < sup > + < /sup > -ATPase and V-ATPase for growth and pathogenicity in pathogenic fungi
Adv Appl Microbiol. 2023;124:31-53. doi: 10.1016/bs.aambs.2023.07.001. Epub 2023 Jul 28.ABSTRACTPathogenic fungi are widespread and cause a variety of diseases in human beings and other organisms. At present, limited classes of antifungal agents are available to treat invasive fungal diseases. With the wide use of the commercial antifungal agents, drug resistance of pathogenic fungi are continuously increasing. Therefore, exploring effective antifungal agents with novel drug targets is urgently needed to cope with the challenges that the antifungal area faces. pH homeostasis is vital for multiple cellular processes, reveal...
Source: Advances in Applied Microbiology - August 19, 2023 Category: Microbiology Authors: S Z Yang L T Peng Source Type: research
Halotolerance mechanisms in salt ‑tolerant cyanobacteria
Adv Appl Microbiol. 2023;124:55-117. doi: 10.1016/bs.aambs.2023.07.003. Epub 2023 Jul 23.ABSTRACTCyanobacteria are ubiquitously distributed in nature and are the most abundant photoautotrophs on Earth. Their long evolutionary history reveals that cyanobacteria have a remarkable capacity and strong adaptive tendencies to thrive in a variety of conditions. Thus, they can survive successfully, especially in harsh environmental conditions such as salty environments, high radiation, or extreme temperatures. Among others, salt stress because of excessive salt accumulation in salty environments, is the most common abiotic stress ...
Source: Advances in Applied Microbiology - August 19, 2023 Category: Microbiology Authors: Hakuto Kageyama Rungaroon Waditee-Sirisattha Source Type: research
Promoters and introns as key drivers for enhanced gene expression in Saccharomyces cerevisiae
Adv Appl Microbiol. 2023;124:1-29. doi: 10.1016/bs.aambs.2023.07.002. Epub 2023 Jul 27.ABSTRACTThe transcription of genes in the yeast Saccharomyces cerevisiae is governed by multiple layers of regulatory elements and proteins, cooperating to ensure optimum expression of the final protein product based on the cellular requirements. Promoters have always been regarded as the most important determinant of gene transcription, but introns also play a key role in the expression of intron-encoding genes. Some introns can enhance transcription when introduced either promoter-proximal or embedded in the open reading frame of genes...
Source: Advances in Applied Microbiology - August 19, 2023 Category: Microbiology Authors: Marthinus Wessel Myburgh Kirstie Susan Schwerdtfeger Rosemary Anne Cripwell Willem Heber van Zyl Marinda Viljoen-Bloom Source Type: research
