The epigenetic regulation of cancer cell recovery from therapy exposure and its implications as a novel therapeutic strategy for preventing disease recurrence
Adv Cancer Res. 2023;158:337-385. doi: 10.1016/bs.acr.2022.11.001. Epub 2023 Jan 6.ABSTRACTThe ultimate goal of cancer therapy is the elimination of disease from patients. Most directly, this occurs through therapy-induced cell death. Therapy-induced growth arrest can also be a desirable outcome, if prolonged. Unfortunately, therapy-induced growth arrest is rarely durable and the recovering cell population can contribute to cancer recurrence. Consequently, therapeutic strategies that eliminate residual cancer cells reduce opportunities for recurrence. Recovery can occur through diverse mechanisms including quiescence or di...
Source: Adv Dent Res - March 29, 2023 Category: Dentistry Authors: Christiana O Appiah Manjulata Singh Lauren May Ishita Bakshi Ashish Vaidyanathan Paul Dent Gordon Ginder Steven Grant Harry Bear Joseph Landry Source Type: research

The epigenetic regulation of cancer cell recovery from therapy exposure and its implications as a novel therapeutic strategy for preventing disease recurrence
Adv Cancer Res. 2023;158:337-385. doi: 10.1016/bs.acr.2022.11.001. Epub 2023 Jan 6.ABSTRACTThe ultimate goal of cancer therapy is the elimination of disease from patients. Most directly, this occurs through therapy-induced cell death. Therapy-induced growth arrest can also be a desirable outcome, if prolonged. Unfortunately, therapy-induced growth arrest is rarely durable and the recovering cell population can contribute to cancer recurrence. Consequently, therapeutic strategies that eliminate residual cancer cells reduce opportunities for recurrence. Recovery can occur through diverse mechanisms including quiescence or di...
Source: Adv Dent Res - March 29, 2023 Category: Dentistry Authors: Christiana O Appiah Manjulata Singh Lauren May Ishita Bakshi Ashish Vaidyanathan Paul Dent Gordon Ginder Steven Grant Harry Bear Joseph Landry Source Type: research

The epigenetic regulation of cancer cell recovery from therapy exposure and its implications as a novel therapeutic strategy for preventing disease recurrence
Adv Cancer Res. 2023;158:337-385. doi: 10.1016/bs.acr.2022.11.001. Epub 2023 Jan 6.ABSTRACTThe ultimate goal of cancer therapy is the elimination of disease from patients. Most directly, this occurs through therapy-induced cell death. Therapy-induced growth arrest can also be a desirable outcome, if prolonged. Unfortunately, therapy-induced growth arrest is rarely durable and the recovering cell population can contribute to cancer recurrence. Consequently, therapeutic strategies that eliminate residual cancer cells reduce opportunities for recurrence. Recovery can occur through diverse mechanisms including quiescence or di...
Source: Adv Dent Res - March 29, 2023 Category: Dentistry Authors: Christiana O Appiah Manjulata Singh Lauren May Ishita Bakshi Ashish Vaidyanathan Paul Dent Gordon Ginder Steven Grant Harry Bear Joseph Landry Source Type: research

The epigenetic regulation of cancer cell recovery from therapy exposure and its implications as a novel therapeutic strategy for preventing disease recurrence
Adv Cancer Res. 2023;158:337-385. doi: 10.1016/bs.acr.2022.11.001. Epub 2023 Jan 6.ABSTRACTThe ultimate goal of cancer therapy is the elimination of disease from patients. Most directly, this occurs through therapy-induced cell death. Therapy-induced growth arrest can also be a desirable outcome, if prolonged. Unfortunately, therapy-induced growth arrest is rarely durable and the recovering cell population can contribute to cancer recurrence. Consequently, therapeutic strategies that eliminate residual cancer cells reduce opportunities for recurrence. Recovery can occur through diverse mechanisms including quiescence or di...
Source: Adv Dent Res - March 29, 2023 Category: Dentistry Authors: Christiana O Appiah Manjulata Singh Lauren May Ishita Bakshi Ashish Vaidyanathan Paul Dent Gordon Ginder Steven Grant Harry Bear Joseph Landry Source Type: research

The epigenetic regulation of cancer cell recovery from therapy exposure and its implications as a novel therapeutic strategy for preventing disease recurrence
Adv Cancer Res. 2023;158:337-385. doi: 10.1016/bs.acr.2022.11.001. Epub 2023 Jan 6.ABSTRACTThe ultimate goal of cancer therapy is the elimination of disease from patients. Most directly, this occurs through therapy-induced cell death. Therapy-induced growth arrest can also be a desirable outcome, if prolonged. Unfortunately, therapy-induced growth arrest is rarely durable and the recovering cell population can contribute to cancer recurrence. Consequently, therapeutic strategies that eliminate residual cancer cells reduce opportunities for recurrence. Recovery can occur through diverse mechanisms including quiescence or di...
Source: Adv Dent Res - March 29, 2023 Category: Dentistry Authors: Christiana O Appiah Manjulata Singh Lauren May Ishita Bakshi Ashish Vaidyanathan Paul Dent Gordon Ginder Steven Grant Harry Bear Joseph Landry Source Type: research

The epigenetic regulation of cancer cell recovery from therapy exposure and its implications as a novel therapeutic strategy for preventing disease recurrence
Adv Cancer Res. 2023;158:337-385. doi: 10.1016/bs.acr.2022.11.001. Epub 2023 Jan 6.ABSTRACTThe ultimate goal of cancer therapy is the elimination of disease from patients. Most directly, this occurs through therapy-induced cell death. Therapy-induced growth arrest can also be a desirable outcome, if prolonged. Unfortunately, therapy-induced growth arrest is rarely durable and the recovering cell population can contribute to cancer recurrence. Consequently, therapeutic strategies that eliminate residual cancer cells reduce opportunities for recurrence. Recovery can occur through diverse mechanisms including quiescence or di...
Source: Adv Dent Res - March 29, 2023 Category: Dentistry Authors: Christiana O Appiah Manjulata Singh Lauren May Ishita Bakshi Ashish Vaidyanathan Paul Dent Gordon Ginder Steven Grant Harry Bear Joseph Landry Source Type: research

The epigenetic regulation of cancer cell recovery from therapy exposure and its implications as a novel therapeutic strategy for preventing disease recurrence
Adv Cancer Res. 2023;158:337-385. doi: 10.1016/bs.acr.2022.11.001. Epub 2023 Jan 6.ABSTRACTThe ultimate goal of cancer therapy is the elimination of disease from patients. Most directly, this occurs through therapy-induced cell death. Therapy-induced growth arrest can also be a desirable outcome, if prolonged. Unfortunately, therapy-induced growth arrest is rarely durable and the recovering cell population can contribute to cancer recurrence. Consequently, therapeutic strategies that eliminate residual cancer cells reduce opportunities for recurrence. Recovery can occur through diverse mechanisms including quiescence or di...
Source: Adv Dent Res - March 29, 2023 Category: Dentistry Authors: Christiana O Appiah Manjulata Singh Lauren May Ishita Bakshi Ashish Vaidyanathan Paul Dent Gordon Ginder Steven Grant Harry Bear Joseph Landry Source Type: research

The epigenetic regulation of cancer cell recovery from therapy exposure and its implications as a novel therapeutic strategy for preventing disease recurrence
Adv Cancer Res. 2023;158:337-385. doi: 10.1016/bs.acr.2022.11.001. Epub 2023 Jan 6.ABSTRACTThe ultimate goal of cancer therapy is the elimination of disease from patients. Most directly, this occurs through therapy-induced cell death. Therapy-induced growth arrest can also be a desirable outcome, if prolonged. Unfortunately, therapy-induced growth arrest is rarely durable and the recovering cell population can contribute to cancer recurrence. Consequently, therapeutic strategies that eliminate residual cancer cells reduce opportunities for recurrence. Recovery can occur through diverse mechanisms including quiescence or di...
Source: Adv Dent Res - March 29, 2023 Category: Dentistry Authors: Christiana O Appiah Manjulata Singh Lauren May Ishita Bakshi Ashish Vaidyanathan Paul Dent Gordon Ginder Steven Grant Harry Bear Joseph Landry Source Type: research

The epigenetic regulation of cancer cell recovery from therapy exposure and its implications as a novel therapeutic strategy for preventing disease recurrence
Adv Cancer Res. 2023;158:337-385. doi: 10.1016/bs.acr.2022.11.001. Epub 2023 Jan 6.ABSTRACTThe ultimate goal of cancer therapy is the elimination of disease from patients. Most directly, this occurs through therapy-induced cell death. Therapy-induced growth arrest can also be a desirable outcome, if prolonged. Unfortunately, therapy-induced growth arrest is rarely durable and the recovering cell population can contribute to cancer recurrence. Consequently, therapeutic strategies that eliminate residual cancer cells reduce opportunities for recurrence. Recovery can occur through diverse mechanisms including quiescence or di...
Source: Adv Dent Res - March 29, 2023 Category: Dentistry Authors: Christiana O Appiah Manjulata Singh Lauren May Ishita Bakshi Ashish Vaidyanathan Paul Dent Gordon Ginder Steven Grant Harry Bear Joseph Landry Source Type: research

The epigenetic regulation of cancer cell recovery from therapy exposure and its implications as a novel therapeutic strategy for preventing disease recurrence
Adv Cancer Res. 2023;158:337-385. doi: 10.1016/bs.acr.2022.11.001. Epub 2023 Jan 6.ABSTRACTThe ultimate goal of cancer therapy is the elimination of disease from patients. Most directly, this occurs through therapy-induced cell death. Therapy-induced growth arrest can also be a desirable outcome, if prolonged. Unfortunately, therapy-induced growth arrest is rarely durable and the recovering cell population can contribute to cancer recurrence. Consequently, therapeutic strategies that eliminate residual cancer cells reduce opportunities for recurrence. Recovery can occur through diverse mechanisms including quiescence or di...
Source: Adv Dent Res - March 29, 2023 Category: Dentistry Authors: Christiana O Appiah Manjulata Singh Lauren May Ishita Bakshi Ashish Vaidyanathan Paul Dent Gordon Ginder Steven Grant Harry Bear Joseph Landry Source Type: research

The epigenetic regulation of cancer cell recovery from therapy exposure and its implications as a novel therapeutic strategy for preventing disease recurrence
Adv Cancer Res. 2023;158:337-385. doi: 10.1016/bs.acr.2022.11.001. Epub 2023 Jan 6.ABSTRACTThe ultimate goal of cancer therapy is the elimination of disease from patients. Most directly, this occurs through therapy-induced cell death. Therapy-induced growth arrest can also be a desirable outcome, if prolonged. Unfortunately, therapy-induced growth arrest is rarely durable and the recovering cell population can contribute to cancer recurrence. Consequently, therapeutic strategies that eliminate residual cancer cells reduce opportunities for recurrence. Recovery can occur through diverse mechanisms including quiescence or di...
Source: Adv Dent Res - March 29, 2023 Category: Dentistry Authors: Christiana O Appiah Manjulata Singh Lauren May Ishita Bakshi Ashish Vaidyanathan Paul Dent Gordon Ginder Steven Grant Harry Bear Joseph Landry Source Type: research

The epigenetic regulation of cancer cell recovery from therapy exposure and its implications as a novel therapeutic strategy for preventing disease recurrence
Adv Cancer Res. 2023;158:337-385. doi: 10.1016/bs.acr.2022.11.001. Epub 2023 Jan 6.ABSTRACTThe ultimate goal of cancer therapy is the elimination of disease from patients. Most directly, this occurs through therapy-induced cell death. Therapy-induced growth arrest can also be a desirable outcome, if prolonged. Unfortunately, therapy-induced growth arrest is rarely durable and the recovering cell population can contribute to cancer recurrence. Consequently, therapeutic strategies that eliminate residual cancer cells reduce opportunities for recurrence. Recovery can occur through diverse mechanisms including quiescence or di...
Source: Adv Dent Res - March 29, 2023 Category: Dentistry Authors: Christiana O Appiah Manjulata Singh Lauren May Ishita Bakshi Ashish Vaidyanathan Paul Dent Gordon Ginder Steven Grant Harry Bear Joseph Landry Source Type: research

The epigenetic regulation of cancer cell recovery from therapy exposure and its implications as a novel therapeutic strategy for preventing disease recurrence
Adv Cancer Res. 2023;158:337-385. doi: 10.1016/bs.acr.2022.11.001. Epub 2023 Jan 6.ABSTRACTThe ultimate goal of cancer therapy is the elimination of disease from patients. Most directly, this occurs through therapy-induced cell death. Therapy-induced growth arrest can also be a desirable outcome, if prolonged. Unfortunately, therapy-induced growth arrest is rarely durable and the recovering cell population can contribute to cancer recurrence. Consequently, therapeutic strategies that eliminate residual cancer cells reduce opportunities for recurrence. Recovery can occur through diverse mechanisms including quiescence or di...
Source: Adv Dent Res - March 29, 2023 Category: Dentistry Authors: Christiana O Appiah Manjulata Singh Lauren May Ishita Bakshi Ashish Vaidyanathan Paul Dent Gordon Ginder Steven Grant Harry Bear Joseph Landry Source Type: research

The epigenetic regulation of cancer cell recovery from therapy exposure and its implications as a novel therapeutic strategy for preventing disease recurrence
Adv Cancer Res. 2023;158:337-385. doi: 10.1016/bs.acr.2022.11.001. Epub 2023 Jan 6.ABSTRACTThe ultimate goal of cancer therapy is the elimination of disease from patients. Most directly, this occurs through therapy-induced cell death. Therapy-induced growth arrest can also be a desirable outcome, if prolonged. Unfortunately, therapy-induced growth arrest is rarely durable and the recovering cell population can contribute to cancer recurrence. Consequently, therapeutic strategies that eliminate residual cancer cells reduce opportunities for recurrence. Recovery can occur through diverse mechanisms including quiescence or di...
Source: Adv Dent Res - March 29, 2023 Category: Dentistry Authors: Christiana O Appiah Manjulata Singh Lauren May Ishita Bakshi Ashish Vaidyanathan Paul Dent Gordon Ginder Steven Grant Harry Bear Joseph Landry Source Type: research

The epigenetic regulation of cancer cell recovery from therapy exposure and its implications as a novel therapeutic strategy for preventing disease recurrence
Adv Cancer Res. 2023;158:337-385. doi: 10.1016/bs.acr.2022.11.001. Epub 2023 Jan 6.ABSTRACTThe ultimate goal of cancer therapy is the elimination of disease from patients. Most directly, this occurs through therapy-induced cell death. Therapy-induced growth arrest can also be a desirable outcome, if prolonged. Unfortunately, therapy-induced growth arrest is rarely durable and the recovering cell population can contribute to cancer recurrence. Consequently, therapeutic strategies that eliminate residual cancer cells reduce opportunities for recurrence. Recovery can occur through diverse mechanisms including quiescence or di...
Source: Adv Dent Res - March 29, 2023 Category: Dentistry Authors: Christiana O Appiah Manjulata Singh Lauren May Ishita Bakshi Ashish Vaidyanathan Paul Dent Gordon Ginder Steven Grant Harry Bear Joseph Landry Source Type: research