Self-guided digital treatment with virtual reality for panic disorder and agoraphobia: a study protocol for a randomized controlled trial
DiscussionThe current study aims at providing insights into the efficacy of short-term treatment applications including psychoeducation and self-guided VRET. If successful, this approach might be a feasible and promising way to ease the burden of PD, AG, and PDA on the public health system and contribute to a faster access to treatment.Trial registrationISRCTNISRCTN10661970. Prospectively registered on 17 January 2022. (Source: Trials)
Source: Trials - May 21, 2022 Category: Research Source Type: clinical trials

Antigravity Treadmill With Alter G on the Postural Stability of Traumatic Lower Limb Injuries
Conditions:   Injury Traumatic;   Muscle Injury;   Bone Injuries Joints;   Tendon Injuries;   Lower Limb Injury;   Ligament Injury Interventions:   Other: Alter G;   Other: Parallel bars and Scale;   Other: Standard rehabilitation protocol Sponsor:   FREMAP Mutual Insurance Company for Occupational Accidents and Diseases Not yet recruiting (Source:
Source: - March 17, 2022 Category: Research Source Type: clinical trials

Improving the continuity and coordination of ambulatory care through feedback and facilitated dialogue —a study protocol for a cluster-randomised trial to evaluate the ACD study (Accountable Care in Germany)
The objectives of this study are to (1) identify informal networks of physicians who treat the same patient population, (2) provide these physicians with feedback on their network and patients, using routine data and (3) give the physicians the opportunity to meet one another in facilitated network meetings.MethodsThe Accountable Care Deutschland (ACD) study is a prospective, non-blinded, cluster-randomised trial comprising a process and economic evaluation of informal networks among 12,525 GPs and office-based specialists and their 1.9 million patients. The units of allocation are the informal networks, which will be rand...
Source: Trials - September 15, 2021 Category: Research Source Type: clinical trials

Assessing the effect of hyperbaric oxygen therapy in breast cancer patients with late radiation toxicity (HONEY trial): a trial protocol using a trial within a cohort design
DiscussionThis pragmatic trial within the UMBELLA cohort was designed to evaluate the effectiveness of HBOT on late radiation toxicity in breast cancer patients using the TwiCs design. Use of the TwiCs design is expected to address issues encountered in classic randomized controlled trials, such as contamination (i.e., HBOT in the control group) and disappointment bias, and generate information about acceptability of HBOT.Trial Registered on 10 December 2019. (Source: Trials)
Source: Trials - November 27, 2020 Category: Research Source Type: clinical trials