Community-based trial of annual versus biannual single-dose ivermectin plus albendazole against Wuchereria bancrofti infection in human and mosquito populations: study protocol for a cluster randomised controlled trial
This study, therefore, seeks to test the hypothesis that biannual treatment of LF-endemic communities will accelerate the interruption of LF in areas of persistent transmission.MethodsA cluster randomised trial will be implemented in LF-endemic communities in Ghana. The interventions will be yearly or twice-yearly MDA delivered to entire endemic communities. Allocation to study group will be by clusters identified using the prevalence of LF. Clusters will be randomised to one of two groups: receiving either (1) annual treatment with IVM + ALB or (2) annual MDA with IVM + ALB, followed by an additional MDA 6 month...
Source: Trials - October 2, 2017 Category: Research Source Type: clinical trials
Fiji Integrated Therapy (FIT) - Triple Therapy for Lymphatic Filariasis, Scabies and Soil Transmitted Helminths in Fiji
Conditions: Lymphatic Filariases; Scabies; Impetigo; Soil Transmitted Helminths Interventions: Drug: 3 drug dose - IDA; Drug: 3 drug dose - IDA with second dose of ivermectin; Drug: 2 drug dose - DA Sponsors: Washington University School of Medicine; The Task Force for Global Health; Murdoch Children's Research Institute Not yet recruiting - verified June 2017 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 31, 2017 Category: Research Source Type: clinical trials
