Controlled, double-blind, randomized trial to assess the efficacy and safety of hydroxychloroquine chemoprophylaxis in SARS CoV2 infection in healthcare personnel in the hospital setting: A structured summary of a study protocol for a randomised controlled trial
DiscussionWhile awaiting a vaccine, hygiene measures, social distancing and personal protective equipment are the only primary prophylaxis measures against SARS-CoV-2, but they have not been sufficient to protect our healthcare professionals. Some evidence of thein vitro efficacy of hydroxychloroquine against this virus is known, along with some clinical data that would support the study of this drug in the chemoprophylaxis of infection. However, there are still no data from controlled clinical trials in this regard. If our hypothesis is confirmed, hydroxychloroquine can help professionals fight this infection with more gu...
Source: Trials - June 2, 2020 Category: Research Source Type: clinical trials
Bicalutamide and Raloxifene Hydrochloride in Treating Patients With Prostate Cancer Undergoing Surgery
Conditions: Stage I Prostate Adenocarcinoma; Stage II Prostate Adenocarcinoma Interventions: Drug: Bicalutamide; Other: Laboratory Biomarker Analysis; Other: Questionnaire Administration; Drug: Raloxifene Hydrochloride Sponsors: Mayo Clinic; National Cancer Institute (NCI) Not yet recruiting - verified May 2017 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 8, 2017 Category: Research Source Type: clinical trials
DP-R213 Phase 1 Pharmacokinetics Study
Condition: Healthy Interventions: Drug: DP-R213; Drug: Raloxifene; Drug: Cholecaliferol Sponsor: Alvogen Korea Not yet recruiting - verified January 2017 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 3, 2017 Category: Research Source Type: clinical trials
