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A Pharmacokinetics (PK) and Safety Study to Determine the Effect of Repeat Dosing of Trametinib on Combined Oral Contraceptive (Norethindrone Plus Ethinyl Estradiol) in Female Subjects With Solid Tumors
Condition:   CancerInterventions:   Drug: Trametinib 0.5 mg;   Drug: Trametinib 2 mg;   Drug: ORTHO-NOVUM® tablet 1/35;   Drug: PlaceboSponsor:   GlaxoSmithKlineNot yet recruiting - verified November 2014 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 13, 2014 Category: Research Source Type: clinical trials

A Pharmacokinetics (PK) and Safety Study to Determine the Effect of Repeat Dosing of Trametinib on Combined Oral Contraceptive (Norethindrone Plus Ethinyl Estradiol) in Female Subjects With Solid Tumors
Condition:   CancerInterventions:   Drug: Trametinib 0.5 mg;   Drug: Trametinib 2 mg;   Drug: ORTHO-NOVUM® tablet 1/35;   Drug: PlaceboSponsor:   GlaxoSmithKlineNot yet recruiting - verified February 2015 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 13, 2014 Category: Research Source Type: clinical trials

A Pharmacokinetics (PK) and Safety Study to Determine the Effect of Repeat Dosing of Trametinib on Combined Oral Contraceptive (Norethindrone Plus Ethinyl Estradiol) in Female Subjects With Solid Tumors
Condition:   CancerInterventions:   Drug: Trametinib 0.5 mg;   Drug: Trametinib 2 mg;   Drug: ORTHO-NOVUM® tablet 1/35;   Drug: PlaceboSponsor:   GlaxoSmithKlineNot yet recruiting - verified March 2015 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 13, 2014 Category: Research Source Type: clinical trials

Effect of Tipranavir and Ritonavir on the Pharmacokinetic Characteristics of Norethindrone-Ethinyl Estradiol in Healthy Female Adult Volunteers
Condition:   HealthyInterventions:   Drug: Tipranavir low dose;   Drug: Tipranavir high dose;   Drug: Ritonavir low dose;   Drug: Ritonavir high dose;   Drug: Norethindrone-Ethinyl EstradiolSponsor:   Boehringer IngelheimTerminated - verified September 2014 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 18, 2014 Category: Research Source Type: clinical trials