Evaluating the safety, tolerability, pharmacokinetics and efficacy of clofazimine in cryptosporidiosis (CRYPTOFAZ): study protocol for a randomized controlled trial
This study provides an opportunity to explore a possible treatment option for HIV-infected patients with cryptosporidial diarrhea, who, as of now in Malawi and most of sub-Saharan Africa, do not have a definitive treatment apart from supportive care. The strength of this study lies in it being a randomized, double-blind, placebo-controlled trial. If shown to be effective and safe, the findings will also lay a foundation for a future study of the use of CFZ in children 6 –18 months of age.Trial registrationClinicalTrials.gov,NCT03341767. Registered on 14 November 2017. (Source: Trials)
Source: Trials - August 23, 2018 Category: Research Source Type: clinical trials

A Phase 2A Evaluation of the Safety, Tolerability, Pharmacokinetics, Efficacy of Clofazimine (CFZ) in Cryptosporidiosis
Condition:   Cryptosporidiosis Interventions:   Drug: Clofazimine;   Drug: Placebo Sponsors:   University of Washington;   Bill and Melinda Gates Foundation;   The EMMES Corporation;   California Institute for Biomedical Research;   Liverpool School of Tropical Medicine;   University of Virginia;   Malawi-Liverpool-Wellcome Trust Clinical Research Programme Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 14, 2017 Category: Research Source Type: clinical trials

Cryptosporidiosis and Enteropathogens in Bangladesh
Condition:   CryptosporidiosisIntervention:   Sponsors:   University of Virginia;   International Centre for Diarrhoeal Disease Research, BangladeshRecruiting - verified May 2016 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 2, 2016 Category: Research Source Type: clinical trials

Diagnosis of Neglected Tropical Diseases Among Patients With Persistent Digestive Disorders
Conditions:   Soil-transmitted Helminthiasis;   Schistosomiasis;   Strongyloidiasis;   Shigellosis;   Intestinal Salmonellosis;   Campylobacteriosis;   Aeromonas Spp. Infections;   Giardiasis;   Amoebiasis;   Dientamoebiasis;   Cryptosporidium Spp. InfectionsInterventions:   Procedure: Stool culturing for pathogenic bacteria;   Procedure: Kato-Katz technique;   Procedure: Baermann technique;   Device: Mini-FLOTAC;   Device: Crypto/Giardia Duo Strip;   Procedure: For...
Source: ClinicalTrials.gov - March 21, 2014 Category: Research Source Type: clinical trials

Trial of Ceramic Water Filters to Reduce Cryptosporidium Infection in Kenya
Conditions:   Cryptosporidium;   Cryptosporidiosis;   Waterborne Disease;   Diarrheal DiseaseIntervention:   Other: Ceramic water filterSponsors:   Centers for Disease Control and Prevention;   Centers for Disease Control and Prevention;   Kenya Medical Research InstituteNot yet recruiting - verified April 2013 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 26, 2012 Category: Research Source Type: clinical trials

Parasitic Infections of the Gastrointestinal Tract
Conditions:   Amebiasis;   Cryptosporidiosis;   Giardiasis;   Parasitic Disease;   Parasitic Intestinal Disease;   Gastrointestinal Helminth InfectionsIntervention:   Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)Recruiting - verified August 2014 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 3, 1999 Category: Research Source Type: clinical trials