Intravenous Nitroglycerine in STEMI, with data: Avoid its use if giving tPA
In conclusion, concurrent nitroglycerin administration reduces the thrombolytic efficacy of rTPA in patients with AMI probably by lowering the plasma levels of rTPA antigen. The diminished efficacy of rTPA is associated with an adverse outcome.References1. Nicolini FA, Ferrini D, Ottani F, et al. Concurrent nitroglycerine therapy impairs tissue-type plasminogen activator-induced thrombolysis in patients with acute myocardial infarction. Am J Cardiol 1994; 74:662-666.2. Mehta JL, Nicolini FA, Nichols WW, Saldeen TG. Concurre...
Source: Dr. Smith's ECG Blog - September 11, 2014 Category: Cardiology Authors: Steve Smith Source Type: blogs
Notes to myself – 2
Pentobarb coma – BIS should be 10-20 and SR (suppression ratio) should be 70-80
Consider lev albuterol
Should give vaccines after coiling of spleen or before if possible
No calcium channel blockers post MI definitely and post op in general
Toradol inhibits spine healing
Don’t do endoscopes with patients in supine position
don’t ambulate patients with known dvt’s. wait 2-3 days until clots get stuck.
dvt’s even with filter get heparin as much as possible for post phlebitic syndrome and to retard new clot formation
diffuse alveolar hemorrhage – secondary to chemo, goodpasture’s, wege...
Source: Inside Surgery - December 31, 2013 Category: Surgeons Authors: Editor Tags: General Source Type: blogs
PCORI News Plus FDA Suggestons on Comparative Effectiveness Research
The Board of Governors of the Patient-Centered Outcomes Research Institute (PCORI) at its 19 November 2012 meeting in Boston, MA adopted 47 revised methodology standards that are intended to guide the comparative effectiveness research (CER) funded by PCORI, reported RAPS. The Board also authorized at the meeting the development of three new CER funding announcements:
Treatment options for uterine fibroids,
the safety and benefits of treatment options for severe asthma, and
fall prevention in the elderly.
One of the bigger pieces of the Patient Protection and Affordable Care Act (PPACA) was the i...
Source: Policy and Medicine - February 14, 2013 Category: Health Medicine and Bioethics Commentators Authors: Thomas Sullivan Source Type: blogs
