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Neoadjuvant Neratinib in Stage I-III HER2-Mutated Lobular Breast Cancers
Conditions:   Anatomic Stage I Breast Cancer;   Anatomic Stage II Breast Cancer;   Anatomic Stage III Breast Cancer;   Invasive Breast Lobular Carcinoma Interventions:   Procedure: Endocrine Therapy;   Procedure: Biopsy of breast;   Drug: Neratinib;   Procedure: Biospecimen Collection;   Procedure: Mammogram;   Procedure: Magnetic Resonance Imaging;   Procedure: Breast Surgery;   Procedure: Ultrasound Sponsors:   Vanderbilt-Ingram Cancer Center;   National Cancer Institute (NCI);   Puma Biotechnology, Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 26, 2023 Category: Research Source Type: clinical trials

A Study of SHR-A1811 as Neoadjuvant Treatment for Patients With HR-Positive, Low HER2 Expression Breast Cancer
Condition:   HER2 Low Breast Carcinoma Intervention:   Drug: SHR-A1811 for injection Sponsor:   Henan Cancer Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 22, 2023 Category: Research Source Type: clinical trials