Tolvaptan versus fluid restriction in acutely hospitalised patients with moderate-profound hyponatraemia (TVFR-HypoNa): design and implementation of an open-label randomised trial
DiscussionWe seek to inform future international guidelines with high-quality data regarding the utility and safety of tolvaptan compared to standard therapy fluid restriction in patients with moderate-severe hyponatraemia in hospital. If tolvaptan use in this patient group is endorsed by our findings, we will have established an evidence-based framework for tolvaptan initiation and monitoring to guide its use.Trial registrationAustralia and New Zealand Clinical Trials RegistryACTRN12619001683123. Registered on December 2 2019 (Source: Trials)
Source: Trials - April 21, 2022 Category: Research Source Type: clinical trials
Treatment of Monosymptomatic Nocturnal Enuresis
Condition: Nocturnal Enuresis Intervention: Other: Rehabilitation Sponsor: University of Alexandria Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 1, 2022 Category: Research Source Type: clinical trials
Randomized Study Of Novel Enuresis Alarm vs Standard Bedwetting Alarm
Conditions: Bedwetting; Nocturnal Enuresis; Urinary Incontinence Interventions: Device: gogoband; Device: SNEA group Sponsors: Yale University; Southwest pediatric Device Consortium; Food and Drug Administration (FDA) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 28, 2022 Category: Research Source Type: clinical trials
