Borrelia burgdorferi is strong inducer of IFN- γ production by human primary NK cells

In conclusion, CD56+ (NK + NK-T) cells produced IFN-γ shortly after exposure to B. burgdorferi and released soluble mediators that were able to activate keratinocytes. These observations underscore the important role of CD56+ (NK + NK-T) cells during early host defence when Borrelia burgdorferi enters the human skin during a tick bite.PMID:35569383 | DOI:10.1016/j.cyto.2022.155895

Source: Cytokine - May 15, 2022 Category: Molecular Biology Authors: Marije Oosting Michelle Brouwer Hedwig D Vrijmoeth Rosa Pascual Domingo Anna Greco Hadewych Ter Hofstede Ellen H van den Bogaard Joost Schalkwijk Mihai G Netea Leo A B Joosten Source Type: research