Evaluating Visual Field Progression in Advanced Glaucoma Using Trend Analysis of Targeted Mean Total Deviation

Purpose:

Trend analysis of visual field (VF) global indices may underestimate the rate of progression in severe glaucoma because of the influence of test points without detectable sensitivity. To test this hypothesis, we compared the rates of change of VF global indices with and without exclusion of undetectable points at various disease stages.

Materials and Methods:

Six hundred and forty-eight eyes of 366 glaucoma patients with 8 or more reliable 30-2 standard automated perimetry over more than 2 years were enrolled. We calculated targeted mean total deviation (TMTD) by averaging total deviation except points which were consistently undetectable in 3 baseline tests. Eyes were classified as early (≥−6 dB), moderate (−6 dB to −12 dB), advanced (−12 dB to −20 dB), and severe (

Source: Journal of Glaucoma - April 1, 2022 Category: Opthalmology Tags: Advances in Glaucoma: Original Studies Source Type: research